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LP36464-3   Microsatellite instability
The appearance of abnormally long or short microsatellites in an individual's DNA is referred to as microsatellite instability. Microsatellite instability (MSI) is a condition manifested by damaged DNA due to defects in the normal DNA repair process. Sections of DNA called microsatellites, which consist of a sequence of repeating units of 1-6 base pairs in length, become unstable and can shorten or lengthen. Microsatellites are also known as simple sequence repeats (SSRs). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP36464-3   Microsatellite instability
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Microsatellite instability:Prid:Pt:Tiss:Nom:Molgen
Long Common Name
Microsatellite instability [Identifier] in Tissue by Molecular genetics method Nominal
Short Name
MSI Tiss
Display Name
Microsatellite instability Molgen Nom (Tiss)
Consumer Name Alpha Get Info
Microsatellite instability, Tissue

Part Model Get Info

  • Component
    Microsatellite instability
    LP36464-3
    • Analyte
      Microsatellite instability
      LP36464-3
      • Component Numerator
        Microsatellite instability
        LP36464-3
        • Component Numerator Core
          Microsatellite instability
          LP36464-3
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Prid
    LP6850-4
  • Time
    Pt
    LP6960-1
  • System
    Tiss
    LP7641-6
    • System Core
      Tiss
      LP7641-6
    • Super System
      NULL
       
  • Scale
    Nom
    LP7750-5
  • Method
    Molgen
    LP6404-0

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.17
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
10809

Language Variants Get Info

TagLanguageTranslation
ar-JOArabic (Jordan)تحديد عدم استقرار المايكروستلايت في الأنسجة ( بتقنية علم الوراثة الجزيئية )
cs-CZCzech (Czechia)Mikrosatelitová nestabilita:Přítomnost nebo identita:Časový bod:Tkáně a stěry:Nominální:Molekulární genetika
el-GRGreek (Greece)Μικροδορυφορική αστάθεια:Prid:Pt:Ιστός:Nom:Μοριακή γενετική
Synonyms: MOLPATH Nom Prid Pt Ιστός Μικροδορυφορική αστάθεια Μοριακή γενετική
es-ESSpanish (Spain)Inestabilidad microsatelite:Presencia o identidad:Punto temporal:Tejido:Nom:Genética molecular
es-MXSpanish (Mexico)Inestabilidad de microsatélites:Presencia o identidad:Punto temporal:Tejido y frotis:Nominal:Genética molecular
fr-FRFrench (France)Microsatellite instabilité:Identification:Ponctuel:Tissu:Résultat nominal:Biologie moléculaire
it-ITItalian (Italy)Microsatelliti, instabilità:Prid:Pt:Tessuto:Nom:Molgen
Synonyms: Genetica molecolare Instabilità dei microsatelliti Patologia molecolare Presenza o Identità Punto nel tempo (episodio) Tessuto & Strisci
nl-NLDutch (Netherlands)microsatellietinstabiliteit:identificator:moment:weefsel en uitstrijkjes:nominaal:moleculair genetisch onderzoek
Synonyms: molgen
pl-PLPolish (Poland)Niestabilność mikrosatelitarna:obecność lub identyfikacja:punkt w czasie:tkanka i rozmazy:skala nominalna:genetyka molekularna
Synonyms: diagnostyka molekularna MSI wynik kategorialny
pt-BRPortuguese (Brazil)Instabilidade de Microsatélites:Ident:Pt:Tecido:Nom:Genética molecular
Synonyms: ; MSI; Identity or presence; Point in time; Random; Tissue; Nominal; PCR; Molecular genetics; Molecular pathology
ru-RURussian (Russian Federation)Микросателлитная нестабильность:ПрИд:ТчкВрм:Тк:Ном:МолГен
Synonyms: Номинальный;Именной Присутствие или Идентификация Ткань и мазки Точка во времени;Момент
tr-TRTurkish (Turkey)Mikrosatellit kararsızlık:MevcKimlik:Zmlı:Doku:Snf:Molgen
zh-CNChinese (China)微卫星不稳定性:存在与否或特征标识:时间点:组织与涂片:名义型:分子遗传学类实验室方法
Synonyms: MSI 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 存在;存在与否;特征标识;身份;身份标识 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=43368-0