LOINC
Version 2.73

43368-0Microsatellite instability [Identifier] in Tissue by Molecular genetics method NominalActive

Part Descriptions

LP36464-3   Microsatellite instability
The appearance of abnormally long or short microsatellites in an individual's DNA is referred to as microsatellite instability. Microsatellite instability (MSI) is a condition manifested by damaged DNA due to defects in the normal DNA repair process. Sections of DNA called microsatellites, which consist of a sequence of repeating units of 1-6 base pairs in length, become unstable and can shorten or lengthen. Microsatellites are also known as simple sequence repeats (SSRs). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP36464-3   Microsatellite instability
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC

Fully-Specified Name

Component
Microsatellite instability
Property
Prid
Time
Pt
System
Tiss
Scale
Nom
Method
Molgen

Additional Names

Short Name
MSI Tiss
Display Name
Microsatellite instability Molgen Nom (Tiss)
Consumer Name Alpha
Microsatellite instability, Tissue

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.17
Last Updated
Version 2.73
Order vs. Observation
Both
Common US Lab Results Rank
10809

Language Variants Get Info

zh-CNChinese (China)
微卫星不稳定性:存在与否或特征标识:时间点:组织与涂片:名义型:分子遗传学类实验室方法
nl-NLDutch (Netherlands)
microsatellietinstabiliteit:identificator:moment:weefsel en uitstrijkjes:nominaal:moleculair genetisch onderzoek
fr-FRFrench (France)
Microsatellite instabilité:Identification:Ponctuel:Tissu:Résultat nominal:Biologie moléculaire
it-ITItalian (Italy)
Microsatelliti, instabilità:Prid:Pt:Tessuto:Nom:Molgen
pt-BRPortuguese (Brazil)
Instabilidade de Microsatélites:Ident:Pt:Tecido:Nom:Genética molecular
ru-RURussian (Russian Federation)
Микросателлитная нестабильность:ПрИд:ТчкВрм:Тк:Ном:МолГен
es-MXSpanish (Mexico)
Inestabilidad de microsatélites:Presencia o identidad:Punto temporal:Tejido y frotis:Nominal:Genética molecular
es-ESSpanish (Spain)
Inestabilidad microsatelite:Presencia o identidad:Punto temporal:Tejido:Nom:Genética molecular
tr-TRTurkish (Turkey)
Mikrosatellit kararsızlık:MevcKimlik:Zmlı:Doku:Snf:Molgen

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=43368-0