43625-3
Acetylcholine receptor Ab [Presence] in Serum
Active
Part Descriptions
LP17722-7 Acetylcholine receptor
An acetylcholine receptor (abbreviated AChR) is an integral membrane protein that responds to the binding of the neurotransmitter acetylcholine. Nicotinic receptors are the primary mediator of the effects of nicotine. In myasthenia gravis, the receptor at the neuromuscular junction (NMJ) is targeted by antibodies, leading to muscle weakness. Muscarinic acetylcholine receptors can be blocked by the drugs atropine and scopolamine. Drugs such as the neuromuscular blocking agents bind reversibly to the nicotinic receptors in the neuromuscular junction and are used routinely in anesthesia. .
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Source: Wikipedia
, Acetylcholine receptor (Wikipedia)
LP36947-7 Acetylcholine receptor Ab
AChR antibodies and striated muscle antibodies have been detected in patients with Myasthenia gravis (MG), thymoma without neurological symptoms, and in patients with other autoimmune diseases, including, for example, Lambert-Eaton disease, myasthenic syndrome, rheumatoid arthritis, systemic lupus erythematosus, Graves disease, and autoimmune liver disease.
AChR antibodies are further characterized into three categories; binding, blocking, and modulating.
ACHR-binding antibodies are detected in 90% of patients with severe, generalized MG, and 50% of patients with ocular MG. ACHR-modulating antibodies and ACHR-blocking antibodies are detected in approximately 65% to 70% of MG patients.
Source: ARUP Laboratories
Fully-Specified Name
- Component
- Acetylcholine receptor Ab
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
Additional Names
- Long Common Name
- Acetylcholine receptor Ab [Presence] in Serum
- Short Name
- AChR Ab Ser Ql
- Display Name
- Acetylcholine receptor Ab Ql (S)
- Consumer Name Alpha Get Info
- Acetylcholine receptor antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.17
- Last Updated
- Version 2.73 (MIN)
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 19519
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG51733-0 | Acetylcholine receptor Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Υποδοχέας ακετυλοχολίνης Αντίσωμα: Synonyms: PrThr Ακετυλοχολίνη Υποδοχέας ακετυλοχολίνης |
es-ES | Spanish (Spain) | Receptor de acetilcolina Anticuerpos: |
es-MX | Spanish (Mexico) | Receptor de acetilcolina Ab: |
et-EE | Estonian (Estonia) | Atsetüülkoliini retseptor antikehad: Synonyms: Järgarvuline Juhuslik Seerum |
fr-CA | French (Canada) | Récepteur de l'acétylcholine, Ac: |
fr-FR | French (France) | Acétylcholine récepteur anticorps: |
fr-BE | French (Belgium) | Récepteur de l'acétylcholine Ac: Synonyms: Anticorps |
it-IT | Italian (Italy) | Acetilcolina, recettore Ab: Synonyms: anticorpo Presenza o Soglia Punto nel tempo (episodio) Recettore dell''acetilcolina Siero Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | acetylcholinereceptor As: Synonyms: acetylcholine receptor antistof; |
pt-BR | Portuguese (Brazil) | Acetilcolina Receptor Ac: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Ацетилхолин рецептор Ат: Synonyms: Антитело Ацетилхолиновый рецептор Порядковый Сыворотка Точка во времени; |
tr-TR | Turkish (Turkey) | Asetilkolin reseptörü Ab: Synonyms: Mevcut |
zh-CN | Chinese (China) | 乙酰胆碱受体 抗体: Synonyms: Ab; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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LOINC Copyright
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