LOINC
Version 2.68

43820-0Bilirubin.direct [Presence] in Serum or PlasmaActive

Part Description

LP15445-7   Bilirubin.glucuronidated+Bilirubin.albumin bound
Bilirubin is an orange-yellow pigment produced by the normal breakdown of heme, a component of the hemoglobin found in red blood cells. It is processed by the liver and excreted in bile. Conditions that cause red blood cell breakdown or interfere with liver or bile processing can cause elevated levels of bilirubin. Bilirubin exists in many forms. Non-glucuronidated bilirubin (also called unconjugated or indirect) is the breakdown product of heme and is not water-soluble. Hemolytic anemias, which cause increased red blood cell breakdown, are one cause of elevated non-glucuronidated bilirubin. Glucuronidated bilirubin (also called conjugated) is a water-soluble form of bilirubin that is made in the liver by the addition of sugar molecules to non-glucuronidated bilirubin. Conditions that affect liver function (such as hepatitis, cirrhosis and liver tumors) or physically block the bile ducts (such as gallstones) can cause elevated levels of glucuronidated bilirubin. A third form of bilirubin is that which is bound to albumin, and it is also known as delta bilirubin because it was originally identified based on the unexpected difference between the total bilirubin level and the level of glucuronidated plus non-glucuronidated bilirubin in some patient samples. Prior to the discovery of albumin-bound bilirubin, the term "direct" bilirubin was used as a synonym for glucuronidated bilirubin, but direct bilirubin is actually glucuronidated plus delta bilirubin (bilirubin covalently bound to albumin). Source: Regenstrief LOINC

Fully-Specified Name

Component
Bilirubin.glucuronidated+Bilirubin.albumin bound
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method

Additional Names

Short Name
Bilirub Direct SerPl Ql
Display Name
Bilirubin.direct Ql

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.17
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2001-2019 American Association for Clinical Chemistry Bilirubin

Language Variants Get Info

zh-CNChinese (CHINA)
胆红素.葡糖醛酸化+胆红素.白蛋白结合型:存在情况或阈值:时间点:血清/血浆:序数型:
nl-NLDutch (NETHERLANDS)
bilirubine.geglucuronideerd + bilirubine.albuminegebonden:aanwezigheid:moment:serum of plasma:ordinaal:
fr-BEFrench (BELGIUM)
Bilirubine.glucuroconjuguée+bilirubine.liée ? l'albumine:PrThr:Temps ponctuel:Sérum/Plasma:Ordinal:
fr-CAFrench (CANADA)
Bilirubine.glucuroconjuguée+bilirubine.liée à l'albumine:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:
fr-FRFrench (FRANCE)
Bilirubine conjuguée+liée à l'albumine:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:
de-DEGerman (GERMANY)
Bilirubin.glucuronidiert+Bilirubin.Albumin gebunden:AKnz:Pkt:Ser/Plas:Ord:
el-GRGreek (GREECE)
Χολερυθρίνη συνδεδεμένη με γλυκουρονίδια+Χολερυθρίνη συνδεδεμένη με λευκωματίνη:PrThr:Χρονική στιγμή:Ορός/Πλάσμα:Τακτική:
it-ITItalian (ITALY)
Bilirubina.glucuronidata+Bbilirubina.albumina legata:PrThr:Pt:Siero/Plasma:Ord:
pt-BRPortuguese (BRAZIL)
Bilirrubina.glicuronizada+Bilirrubina.ligada a albumina:ACnc:Pt:Sor/Plas:Ord:
ru-RURussian (RUSSIAN FEDERATION)
Билирубин.глюкоронат+Билирубин.альбумин связанный:PrThr:ТчкВрм:Сыв/Плаз:Пор:
es-ESSpanish (SPAIN)
Bilirrubina conjugada + bilirrubina unida a albúmina:PrThr:Punto temporal:Suero o Plasma:Ord:
tr-TRTurkish (TURKEY)
Bilirubin.glukuronize+Bilirubin.albumine bağlı:MevcEşik:Zmlı:Ser/Plaz:Srl:

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=43820-0