44284-8

2-Methylcitrate/Creatinine [Molar ratio] in 24 hour Urine

Active

Part Descriptions

LP18136-9 2-Methylcitrate
Elevated methylcitric acid levels are indicative of an underlying metabolic disorder such as methylmalonic acidemia (MMA) and propionic acidemia (PA). Source: Regenstrief LOINC

LP18136-9 2-Methylcitrate
2-Methylcitrate (methylcitric acid (MCA)) is measured as a second-tier assay when abnormal propionyl carnitine or methionine concentrations are identified in a primary newborn screen. Methylmalonic acidemia (MMA) and propionic acidemia (PA) are defects of propionate metabolism caused by deficiencies in methylmalonyl-CoA mutase and propionyl-CoA carboxylase, respectively. The clinical phenotype of both conditions includes vomiting, hypotonia, lethargy, apnea, hypothermia, and coma in the newborn period, and both MMA and PA are associated with elevated MCA and propionyl carnitine concentrations. MMA and PA can be distinguished based on methylmalonic acid concentration, which is elevated in MMA and normal in PA. Source: Regenstrief LOINC

LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

LOINC Names Get Info

Fully-Specified Name: 2-Methylcitrate/Creatinine:SRto:24H:Urine:Qn:
Long Common Name: 2-Methylcitrate/Creatinine [Molar ratio] in 24 hour Urine
Short Name: 2Me-citrate/Creat 24h Ur-sRto
Display Name: 2-Methylcitrate/Creatinine (24H U) [Molar ratio]
Consumer Name Alpha Get Info: 2-Methylcitrate/Creatinine, Urine

Part Model Get Info

Component
2-Methylcitrate/Creatinine
LP284714-5
- Analyte
  2-Methylcitrate/Creatinine
  LP284714-5
  - Component Numerator
    2-Methylcitrate
    LP18136-9
    - Component Numerator Core
      2-Methylcitrate
      LP18136-9
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Creatinine
    LP32035-5
    - Component Denominator Core
      Creatinine
      LP32035-5
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
SRto
LP6868-6
Time
24H
LP6924-7
- Time Core
  24H
  LP6924-7
- Time Modifier
  NULL
System
Urine
LP7681-2
- System Core
  Urine
  LP7681-2
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.17
Last Updated: Version 2.42 (MIN)
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG35318-1	2-Methylcitrate/Creatinine\|SRto\|Urine

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	2-methylcitrát/kreatinin:Látkový poměr:24 hodin:Moč:Kvantitativní:
de-AT	German (Austria)	Synonyms: 2-Methylcitrat/Kreatinin-Ratio /24hU
el-GR	Greek (Greece)	Κιτρικό 2-μεθύλιο/Κρεατινίνη:SRto:24H:Ούρα:Qn: Synonyms: 24H CHEM Qn SRto Κιτρικό 2-μεθύλιο Κρεατινίνη Ούρα
es-ES	Spanish (Spain)	2-Metilcitrato/Creatinina:Relacion de Sustancia:24 horas:Orina:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	2-metilcitrato / creatinina:Proporción de sustancia:24H:Orina:Cuantitativo:
fr-CA	French (Canada)	2-méthylcitrate/Créatinine:Ratio de substance:24 h:Urine:Quantitatif:
fr-FR	French (France)	2-méthylcitrate/créatinine:Moles ratio:24H:Urine:Numérique:
fr-BE	French (Belgium)	2-méthylcitrate/Créatinine:Ratio de substance:24 h:Urine:Quantitatif:
it-IT	Italian (Italy)	2-Metilcitrato/Creatinina:Srto:24h:Urine:Qn: Synonyms: 24 Ore Chimica Rapporto di sostanza
nl-NL	Dutch (Netherlands)	2-methylcitraat/creatinine:molaire verhouding:24 uur:urine:kwantitatief: Synonyms: 24U kreatinine
pl-PL	Polish (Poland)	2-Metylocytrynian/kreatynina:współczynnik molowy:24h:mocz:ilościowy: Synonyms: 24 godziny
pt-BR	Portuguese (Brazil)	2-Metilcitrato/Creatinina:SCrto:24H:Urina:Qn: Synonyms: ; 2Me-citrate; Methylcitric acid; Creat; CR; 2Me-citrate; sRto; Substance concentration ratio; 1 day; 24 hours; 24HR; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; II; Chemistry; UCr
ru-RU	Russian (Russian Federation)	2-Метилцитрат/Креатинин:МольОтн:24 часа:Моча:Колич: Synonyms: Количественный Мольная доля;Молярная доля;Отношение концентраций
tr-TR	Turkish (Turkey)	2-Metilsitrat/Kreatinin:SOrn:24Sa:İdrar:Kant: Synonyms: SubsOranı
zh-CN	Chinese (China)	2-甲基柠檬酸/肌酐:物质的量比率:24小时:尿液:定量型: Synonyms: 1天;1日;24.0小时;一天;一日;二十四个小时;二十四小时 2Me-柠檬酸;Me-柠檬酸;甲基柠檬酸 Ⅱ CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 II UCr 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺尿;小便;下泉尿液肌酐尿液肌酸酐尿肌酸酐物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值肌酸内酰胺

Example Units

Unit	Source
mmol/mol{creat}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.