44321-8
Interleukin 5 [Presence] in Serum or Plasma
Active
Part Descriptions
LP16473-8 Interleukin 5
Interleukin 5 or IL-5 is an interleukin produced by T helper-2 cells and mast cells. Its functions are to stimulate B cell growth and increase immunoglobulin secretion. It is also a key mediator in eosinophil activation. IL-5 is a 115 amino acid (in man, 133 in the mouse) long TH2 cytokine which is part of the hematopoietic family.Interleukin-5 is also expressed by eosinophils and has been observed in the mast cells of asthmatic airways by immunohistochemistry. IL-5 expression is regulated by several transcription factors including GATA3.
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Source: Wikipedia, Wikipedia
LP16473-8 Interleukin 5
The Interleukins belong to the family termed cytokines. They are peptides used by immune and inflammatory cells to communicate and control cell operations. The cytokines have some similar actions to the Growth Factors but Growth Factors regulate proliferation of non-immune cells. Interleukin 5 is a 50,000-60,000 molecular weight glycoprotein originally called T Cell Replacing Factor. It is released primarily by activated T Cells. Its primary target cells are B cells and eosinophils. Interleukin 5 activates B cell differentiation. Its actions are similar to Interleukin 3. Interleukin 5 primes basophils for agonist-induced generation of Leukotriene C4. It is stimulated by Interleukin 2. Interleukin 5 stimulates growth and differentiation of eosinophil progenitor without influencing cells committed to neutrophils, basophils, or monocytes. It enhances responsiveness of eosinophils inducing polarization, shape change, chemotaxis, cytotoxity, oxygen radical release and prolongs survival.
Source: Inter Science Institute, Inter Science Institute
Fully-Specified Name
- Component
- Interleukin 5
- Property
- PrThr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Ord
- Method
Additional Names
- Short Name
- Il5 SerPl Ql
- Display Name
- Interleukin 5 Ql
- Consumer Name Alpha Get Info
- Interleukin 5, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.17
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Interleuquina 5: |
| es-MX | Spanish (Mexico) | Interleucina 5: |
| et-EE | Estonian (Estonia) | Interleukiin 5: Synonyms: Järgarvuline Juhuslik Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Interleukine 5: |
| fr-FR | French (France) | Interleukine-5: |
| fr-BE | French (Belgium) | Interleukine 5: Synonyms: Il5 |
| it-IT | Italian (Italy) | Interleuchina 5: Synonyms: Chimica Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | interleukine 5: |
| pt-BR | Portuguese (Brazil) | Interleucina 5: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Интерлейкин 5: Synonyms: Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | İnterlökin 5: Synonyms: Mevcut |
| zh-CN | Chinese (China) | 白细胞介素 5: Synonyms: B 细胞生长因子-II; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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