44332-5

Jo-1 extractable nuclear IgG Ab [Presence] in Serum

Active

Part Description

LP16719-4 Jo-1 extractable nuclear
Aminoacyl-tRNA synthetases (ARS) are enzymes that link amino acids to tRNA molecules and therefore play a key role in protein synthesis. Each ARS is specific for a single amino acid. [NCBI Books: NBK22356] Autoantibodies to ARS are a hallmark of connective tissue diseases including anti-synthetase syndrome (ASS) and idiopathic inflammatory myopathies such as polymyositis (PM) and dermatomyositis (DM). ASS, PM and DM have overlapping features, including myositis, arthralgia, skin manifestations and interstitial lung disease. Antibodies to several specific ARS enzymes have been identified, including anti-histidyl (anti-Jo-1), anti-threonyl (anti-PL-7), anti-alanyl (anti-PL-12), anti-glycyl (anti-Ej), anti-isoleucyl (anti-Oj), anti-asparaginyl (anti-Ks), anti-phenylalanyl (anti-Zo), and anti-tyrosyl (anti-Ha). Different antibodies or patterns of antibodies have been associated with specific clinical features. Anti-Jo-1, anti-Ej, and anti-PL-7 antibodies are associated with myositis, including classic DM, clinically amyopathic DM (CADM) and PM. Anti-PL-12 alone is associated with CADM or interstitial lung disease (ILD). Anti-Ej and anti-PL-12 together are associated with CADM. Anti-Ks and anti-Oj are associated with ILD alone. PMID: 23573256 Anti-Ha and anti-Zo antibodies are the most recent autoantibodies to be identified in patients with symptoms of ASS. PMID: 17392287 Identifying the particular anti-ARS antibodies associated with an individual patient's disease may help guide treatment and predict clinical outcomes. Source: Regenstrief LOINC, PMID: 23573256

LOINC Names Get Info

Fully-Specified Name: Jo-1 extractable nuclear Ab.IgG:PrThr:Pt:Ser:Ord:
Long Common Name: Jo-1 extractable nuclear IgG Ab [Presence] in Serum
Short Name: ENA Jo1 IgG Ser Ql
Display Name: Jo-1 extractable nuclear IgG Ql (S)
Consumer Name Alpha Get Info: Jo-1 extractable nuclear IgG antibody, Blood

Part Model Get Info

Component
Jo-1 extractable nuclear Ab.IgG
LP38742-0
- Analyte
  Jo-1 extractable nuclear Ab.IgG
  LP38742-0
  - Component Numerator
    Jo-1 extractable nuclear Ab.IgG
    LP38742-0
    - Component Numerator Core
      Jo-1 extractable nuclear
      LP16719-4
    - Component Numerator Core Suffix
      Ab.IgG
      LP32401-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Ord
LP7751-3
Method
NULL

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.17
Last Updated: Version 2.73 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 2158

Member of these Groups Get Info

LOINC Group	Group Name
LG17624-4	Jo-1 extractable nuclear Ab.IgG\|PrThr\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Antinukleární protilátky IgG Jo-1 extrahovatelné:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:
el-GR	Greek (Greece)	εκχυλίσιμα πυρηνικά αντιγόνα Jo-1 Αντισώματα IgG:PrThr:Pt:Ορός:Ord: Synonyms: Ord PrThr Pt SERO Ανοσοσφαιρίνη G Αντίσωμα Αντισώματα IgG Εκχυλίσιμα πυρηνικά εκχυλίσιμα πυρηνικά αντιγόνα Jo-1 Ορός Πυρηνικό
es-ES	Spanish (Spain)	Jo-1 IgG:PrThr:Punto temporal:Suero:Ord:
es-MX	Spanish (Mexico)	Ab.IgG nuclear extraíble con Jo-1:Presencia o umbral:Punto temporal:Suero:Ordinal:
fr-CA	French (Canada)	Jo-1 nucléaire soluble, IgG:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:
fr-FR	French (France)	Jo-1 Ac IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:
fr-BE	French (Belgium)	Jo-1 nucléaire soluble Anticorps. IgG:PrThr:Temps ponctuel:Sérum:Ordinal: Synonyms: Anticorps
it-IT	Italian (Italy)	Jo-1, nucleare estraibile Ab.IgG:PrThr:Pt:Siero:Ord: Synonyms: anticorpi IgG anticorpo ENA Jo1 Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL	Dutch (Netherlands)	jo-1 extraheerbaar nucleair As.IgG:aanwezigheid:moment:serum:ordinaal: Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Jo-1 rozpuszczalny jądrowy Ab.IgG:granica wykrywalności:punkt w czasie:surowica:uporządkowany: Synonyms: IgG Jo-1 rozpuszczalny jądrowy Przeciwciała do rozpuszczalnego antygenu jądrowego Przeciwciała do rozpuszczalnego jądrowego antygenu Jo-1 przeciwciała IgG Przeciwciała IgG do jądra komórkowego Przeciwciała IgG do rozpuszczalnego jądrowego antygenu Jo-1 Przeciwciała przeciwjądrowe
pt-BR	Portuguese (Brazil)	Jo-1 Ac.IgG:ACnc:Pt:Soro:Ord: Synonyms: ; ANA; ANF; NA; Antinuclear antibody; Nuc; ENA Jo1; Histidyl-tRNA synthease; Immune globulin G; Immunoglobulin G; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; I; Serology
ru-RU	Russian (Russian Federation)	Jo-1 экстрагируемый ядерный Ат.IgG:PrThr:ТчкВрм:Сыв:Пор: Synonyms: Антитело Порядковый Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	Jo-1 öztlenebilir çekirdek Ab.IgG:MevcEşik:Zmlı:Ser:Srl: Synonyms: Ak Ak.IgG Çekirdek Mevcut
zh-CN	Chinese (China)	Jo-1 可提取性核抗体.IgG:存在情况或阈值:时间点:血清:序数型: Synonyms: Ⅰ Ab.IgG;IgG;抗体 IgG Ab;自身抗体 ANA ENA Ab ENA Jo1 Ab ENA Jo-1 Ab ENA Jo1 Ab.IgG ENA Jo-1 Ab.IgG ENA Jo1 IgG ENA Jo-1 IgG ENA Jo1 抗体 ENA Jo-1 抗体 ENA Jo1 抗体.IgG ENA Jo-1 抗体.IgG ENA Jo1;ENA Jo-1;Jo-1 可提取性核 Ag;Jo-1 可提取性核抗原;可提取性核 Ag Jo1;可提取性核 Ag Jo-1;可提取性核抗原 Jo1;可提取性核抗原 Jo-1;组氨酰-tRNA 合成酶;组氨酰基-tRNA 合成酶 ENA 抗体 ENA;可提取性核 Ag;可提取性核抗原;可提取性核抗原（Extractable Nuclear Antigen，ENA）;可提取性细胞核;可提取性细胞核 Ag;可提取性细胞核抗原;盐水可提取性核 Ag;盐水可提取性核抗原;盐水可提取性细胞核 Ag;盐水可提取性细胞核抗原 I Jo1 可提取性核 Ab Jo-1 可提取性核 Ab Jo1 可提取性核 Ab.IgG Jo-1 可提取性核 Ab.IgG Jo1 可提取性核 Ag Ab Jo-1 可提取性核 Ag Ab Jo1 可提取性核 Ag Ab.IgG Jo-1 可提取性核 Ag Ab.IgG Jo1 可提取性核抗体 Jo1 可提取性核抗体.IgG Jo1 可提取性核抗原抗体 Jo-1 可提取性核抗原抗体 Jo1 可提取性核抗原抗体.IgG Jo-1 可提取性核抗原抗体.IgG NA 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫球蛋白 G 可提取性核 Ab 可提取性核 Ag Jo1 Ab 可提取性核 Ag Jo-1 Ab 可提取性核 Ag Jo1 Ab.IgG 可提取性核 Ag Jo-1 Ab.IgG 可提取性核 Ag 之 Ab 可提取性核抗原 Jo1 IgG 可提取性核抗原 Jo-1 IgG 可提取性核抗原 Jo1 抗体可提取性核抗原 Jo-1 抗体可提取性核抗原 Jo1 抗体.IgG 可提取性核抗原 Jo-1 抗体.IgG 可提取性核抗原之抗体存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）抗 ENA 抗可提取性核 Ag 抗可提取性核抗原抗核 Ab 抗核抗体抗核抗体（Antinuclear antibody，ANA）时刻;随机;随意;瞬间核;胞核核心抗体IgG 核心抗原抗体.IgG 核心抗原抗体IgG 核抗体.IgG 核抗体IgG 核抗原抗体.IgG 核抗原抗体IgG 细胞核 Ab 细胞核 Ab.IgG 细胞核 IgG 胞核 Ab 胞核 Ab.IgG 胞核抗体胞核抗体.IgG 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.