44364-8
Glutarate/Creatinine [Molar ratio] in 24 hour Urine
Active
Part Descriptions
LP18437-1 Glutarate
Glutaric acid (IUPAC systematic name:pentanedioic acid) is a simple five-carbon linear dicarboxylic acid.
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Source: Wikipedia, Glutarate (Wikipedia)
LP18437-1 Glutarate
Glutaric acid (glutarate) is a simple five-carbon linear dicarboxylic acid. The accumulation of glutaric acid ranging from slightly or intermittently elevated urinary glutaric acid to gross organic aciduria occurs in Glutaric aciduria. Glutaric aciduria type 1 is an autosomal-recessive disorder resulting from a deficiency of mitochondrial glutaryl-CoA dehydrogenase (EC 1.3.99.7, GCDH) which is involved in the metabolism of lysine, hydroxylysine, and tryptophan. Glutaric aciduria type I lead to nonspecific developmental delay, hypotonia, and macrocephaly with cerebral atrophy of prenatal onset. Treatment is mainly based on restriction of lysine intake, supplementation of carnitine, and an intensification of therapy during intercurrent illnesses. The major principle of dietary treatment is to reduce the production of glutaric acid and 3-hydroxyglutaric acid by restriction of natural protein in general and of lysine in particular. PMID: 17465389, PMID: 15505398
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- Glutarate/Creatinine
- Property
- SRto
- Time
- 24H
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Short Name
- Glutarate/Creat 24h Ur-sRto
- Display Name
- Glutarate/Creatinine (24H U) [Molar ratio]
- Consumer Name Alpha Get Info
- Glutarate/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.17
- Last Updated
- Version 2.42
- Order vs. Observation
- Both
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG35410-6 | Glutarate/Creatinine| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: Glutarsäure/Kreatinin-Ratio /24hU |
es-ES | Spanish (Spain) | Glutarato/Creatinina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Glutarato / Creatinina: |
fr-CA | French (Canada) | Glutarate/Créatinine: |
fr-FR | French (France) | Glutarate/créatinine: |
fr-BE | French (Belgium) | Glutarate/Créatinine: |
it-IT | Italian (Italy) | Glutarato/Creatinina: Synonyms: 24 Ore Chimica Rapporto di sostanza |
nl-NL | Dutch (Netherlands) | glutaraat/creatinine: Synonyms: 24U kreatinine |
pt-BR | Portuguese (Brazil) | Glutarato/Creatinina: Synonyms: Pentanedioic acid; |
ru-RU | Russian (Russian Federation) | Глутарат/Креатинин: Synonyms: Количественный Мольная доля; |
tr-TR | Turkish (Turkey) | glutarat/Kreatinin: Synonyms: SubsOranı |
zh-CN | Chinese (China) | 戊二酸/肌酐: Synonyms: 1天; |
Example Units
Unit | Source |
---|---|
mmol/mol{creat} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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