44409-1

Succinate/Creatinine [Molar ratio] in 24 hour Urine

Active

Part Descriptions

LP15871-4   Succinate
Succinic acid (IUPAC systematic name:butanedioic acid ; historically known as spirit of amber) is a dicarboxylic acid. At room temperature, pure succinic acid is a solid that forms colorless, odorless prisms. It has a melting point of 185°C and a boiling point of 235°C. The anion, succinate, is a component of the citric acid cycle and is capable of donating electrons to the electron transfer chain via the following reaction: succinate + FAD †' fumarate + FADH2 This is catalysed by the enzyme succinate dehydrogenase (or complex II of the mitochondrial ETC). The complex is a 4 subunit membrane-bound lipoprotein which couples the oxidation of succinate to the reduction of ubiquinone. Intermediate electron carriers are FAD and three Fe2 S2 clusters part of subunit B. Esters of succinic acid are called dialkyl succinates. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Succinate (Wikipedia)

LP15871-4   Succinate
Succinic acid is a dicarboxylic acid that increases due to a riboflavin or coenzyme Q-10 deficiency or bacterial conversion of glutamine to succicinic acid in the gastrointestinal tract. Elevated levels may be due to succinic semialdehyde dehydrogenase deficiency, malonic acidura, or fumarase deficiency. Source: Regenstrief Institute

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Fully-Specified Name

Component

Succinate/Creatinine

Property

SRto

Time

24H

System

Urine

Scale

Qn

Method

Additional Names

Short Name

Succinate/Creat 24h Ur-sRto

Display Name

Succinate/Creatinine (24H U) [Molar ratio]

Consumer Name Alpha Get Info

Succinate/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.17

Last Updated

Version 2.42

Order vs. Observation

Both

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 1 day
• 24 hours
• 24HR
• Butanedioate
• Butanedioic acid
• Chemistry
• CR
• Crea
• Creat
• QNT
• Quan
• Quant
• Quantitative
• Scrto
• Substance concentration ratio
• Substance ratio
• Succinic acid
• UA
• UCr
• UR
• Urn

Example Units

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