44583-3

IgA Ab [Presence] in Serum or Plasma by Hemagglutination inhibition

Active

Part Descriptions

LP14669-3   IgA
Immunoglobulin A (IgA) is a glycoprotein that plays a critical role in mucosal immunity. More IgA is produced in mucosal linings than all other immunoglobulins (IgG,IgM,IgE), combined; between 3 and 5g are secreted into the intestinal lumen each day. IgA, in its secretory form, is the main immunoglobulin found in mucous secretions, including tears, saliva, colostrum, intestinal juice, vaginal fluid and secretions from the prostate and respiratory epithelium. It is also found in small amounts in blood. Because it is resistant to degradation by enzymes, secretory IgA can survive in harsh environments such as the digestive and respiratory tracts, thus providing a first line of defense against pathogens that multiply in body secretions. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, IgA

LP6304-2   HAI
The hemagglutination-inhibition assay (HAI) can be used to identify subtypes of hemagglutinin producing viruses, such as Influenza. HAI can also be used to identify the subtype-specificity of antibodies against the virus. Normally, Influenza's hemagglutinin glycoprotein binds to receptors on the surface of red blood cells, causing them to agglutinate. If antibodies specific to the virus are present in the patient sample, they will bind to the virus, which prevents the virus from binding to the red blood cells and therefore prevents agglutination. To determine which subtype of virus is present, a viral isolate is tested against a series of antibodies with known subtype specificities. Whichever antibody inhibits red cell agglutination identifies the viral subtype. Similarly, antibody specificity is identified by testing the patient sample against known virus subtypes. PMID: 24899416 Source: Regenstrief LOINC

Fully-Specified Name

Component

IgA Ab

Property

PrThr

Time

Pt

System

Ser/Plas

Scale

Ord

Method

HAI

Additional Names

Short Name

IgA Ab SerPl Ql HAI

Display Name

IgA Ab HAI Ql

Consumer Name Alpha Get Info

IgA antibody, Blood

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.17

Last Updated

Version 2.56

Change Reason

The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Member of these Groups Get Info

Language Variants Get Info

Related Names

• ABS
• Aby
• Antby
• Anti
• Antibodies
• Antibody
• Autoantibodies
• Autoantibody
• Chemistry
• HEMAGGLUTINATION INHIBITION
• HI
• Immune globulin A
• Immunoglobulin A
• Ordinal
• Pl
• Plasma
• Plsm
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Screen
• SerP
• SerPl
• SerPlas
• Serum
• Serum or plasma
• SR

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.

CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=44583-3

LOINC Copyright

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.