Log In

Part Description

LP72957-1   Mitotic index
Mitotic index is a measure for the proliferation status of a cell population. It is defined as the ratio between the number of cells in mitosis and the total number of cells. Cells in the cell cycle can be identified using antibodies against the nuclear antigen Ki-67. The mitotic index can be worked out from a slide, even with light microscopy. It is the number of cells containing visible chromosomes divided by the total number of cells in the field of view.

If you administer colchicine or other colchicine-derivative medications (i.e. colcemid) you can arrest the cell cycle at this point leaving the chromosomes in their visible form. Colchicine disrupts the microtubule formation which is necessary for the spindle fibers to separate the chromosomes during anaphase.

By quantifying aspects of a dividing cell population, we can examine how cells differ in their capability to divide. Experimentally, we can change properties of the cell's environment and quantify the effects on cell division.

For a group of cells that rarely complete the cell cycle, we expect a high proportion of cells to be in the resting stage of the cell cycle (G1). However, in a rapidly dividing cell population, we expect a high proportion of cells to be in the stage of mitosis. One way to quantify cell division is by using the mitotic index: Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LOINC Names Get Info

Fully-Specified Name
Mitotic index:Find:Pt:Skin melanoma:Nom:CAP cancer protocols
Long Common Name
Mitotic index by CAP cancer protocols
Short Name
Mitotic index CAP prot
Display Name
Mitotic index CAP Nom (Skin melanoma)
Consumer Name Alpha Get Info
Mitotic index, Skin Melanoma

Part Model Get Info

  • Component
    Mitotic index
    LP72957-1
    • Analyte
      Mitotic index
      LP72957-1
      • Component Numerator
        Mitotic index
        LP72957-1
        • Component Numerator Core
          Mitotic index
          LP72957-1
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Find
    LP6813-2
  • Time
    Pt
    LP6960-1
  • System
    Skin melanoma
    LP36756-2
    • System Core
      Skin melanoma
      LP36756-2
    • Super System
      NULL
       
  • Scale
    Nom
    LP7750-5
  • Method
    CAP cancer protocols
    LP32200-5

Basic Attributes

Class
PATH.PROTOCOLS.SKIN
Type
Laboratory
First Released
Version 2.17
Last Updated
Version 2.38 (MIN)
Order vs. Observation
Observation

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Mitotický index:Nález:Časový bod:Kožní melanom:Nominální:Histopatologické protokoly CAP (College of American Pathologists)
el-GRGreek (Greece)Μιτωτικός δείκτης:Εύρεση:Pt:Δερματικό μελάνωμα:Nom:Πρωτόκολλα CAP για τον καρκίνο
Synonyms: Nom PATH PATH.PROTOCOLS.SKIN Pt Δέρμα Δερματικό μελάνωμα Εύρεση Μιτωτικός δείκτης Πρωτόκολλα CAP για τον καρκίνο
es-ESSpanish (Spain)Indice mitótico:Hallazgo:Punto temporal:Melanoma de piel:Nom:Protocolo CAP de cáncer
es-MXSpanish (Mexico)Índice mitótico:Hallazgo:Punto temporal:Melanoma de piel:Nominal:Protocolos de cáncer de CAP
it-ITItalian (Italy)Indice mitotico:Osservazione:Pt:Melanoma della pelle:Nom:Protocolli cancro CAP
Synonyms: Osservazione Patologia Protocolli neoplasia maligna CAP Protocolli patologia - pelle Punto nel tempo (episodio)
nl-NLDutch (Netherlands)mitotische index:bevinding:moment:huidmelanoma:nominaal:CAP-kankerprotocollen
Synonyms: huidmelanoom
pt-BRPortuguese (Brazil)Índice mitótico:Achado:Pt:Melanoma de pele:Nom:Protocolos de cancer do CAP
Synonyms: Finding; Findings; Point in time; Random; Epidermis; Skn; Integument; Dermatologic; Nominal; CAP protocol; PATHOLOGY PROTOCOLS SKIN
tr-TRTurkish (Turkey)Mitotik indeks:Bulgu:Zmlı:Deri melanoma:Snf:CAP kanser protokolleri
zh-CNChinese (China)有丝分裂指数:发现:时间点:皮肤黑色素瘤:名义型:美国病理学家协会癌症方案
Synonyms: CAP 癌症方案;美国病理协会癌症方案 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 发现是一个原子型临床观察指标，并不是作为印象的概括陈述。体格检查、病史、系统检查及其他此类观察指标的属性均为发现。它们的标尺对于编码型发现可能是名义型，而对于叙述型文本之中所报告的发现，则可能是叙述型。;发现物;所见;结果;结论 时刻;随机;随意;瞬间 病理学.方案 病理学.方案.皮肤;病理学原始记录.皮肤;病理学方案.皮肤;皮肤病理学原始记录 病理学原始记录 病理学方案 皮;肤;表皮 皮肤黑瘤;皮肤黑素瘤 细胞有丝分裂指数

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=44695-5