Version 2.78

Part Descriptions

LP16379-7   Complement C7
A 93-kDa serum glycoprotein encoded by C7 gene. It is a polypeptide chain with 28 disulfide bridges. In the formation of membrane attack complex, C7 is the next component to bind the C5b-6 complex forming a trimolecular complex C5b-7. C5b-7 is lipophilic, resembles an integral membrane protein, and serves as an anchor for the late complement components, C8 and C9. Source: National Library of Medicine, MeSH 2006

LP16379-7   Complement C7
The complement system is a key part of the immune system and inflammatory response. The system has three pathways: 1) the classic pathway, 2) the alternative pathway, and 3) the lectin activation pathway. Complement C7 is involved in the alternate complement pathway and one of the late activation complement proteins along with C5, C6, C8, and C9. Patients with deficiencies of the late complement proteins are unable to form the membrane attack complex (MAC), the end result of the complement activation cascade. Patients with C7 deficiency have increased susceptibility to neisserial infections and some have developed systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), scleroderma, and pyoderma gangrenosum. Complement tests measure either the quantity or the activity (function) of complement proteins. In some cases, complement proteins are present but not functional, in which case a functional assay is used to detect the deficiency. Source: Regenstrief LOINC

Fully-Specified Name

Component
Complement C7
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
C7 SerPl-mCnc
Display Name
Complement C7 [Mass/Vol]
Consumer Name Alpha Get Info
Complement C7, Blood

Basic Attributes

Class
HEM/BC
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
12320

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) fracción C7 del complemento:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ES Spanish (Spain) Complemento C7:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Complemento C7:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE Estonian (Estonia) Komplemendi komponent C7:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA French (Canada) Complément C7:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Complément C7:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Complément C7:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT Italian (Italy) Complemento C7:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Ematologia (coagulazione) conta differenziale Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR Korean (Korea, Republic Of) 도움체 C7:질량농도:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) complement C7:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Complemento C7:MCnc:Pt:Sor/Plas:Qn:
Synonyms: ; Comp; Complmt; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; HEMATOLOGY/CELL COUNTS; HEMATOLOGY/CELL COUNTS
ru-RU Russian (Russian Federation) Комплемент C7:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Kompleman C7:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 补体 C7:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 血液学/细胞计数;血液学与细胞计数 血清或血浆

Example Units

Unit Source
mg/L Example UCUM Units
mg/L eCHN

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=4508-8