4508-8

Complement C7 [Mass/volume] in Serum or Plasma

Active

Part Descriptions

LP16379-7 Complement C7
A 93-kDa serum glycoprotein encoded by C7 gene. It is a polypeptide chain with 28 disulfide bridges. In the formation of membrane attack complex, C7 is the next component to bind the C5b-6 complex forming a trimolecular complex C5b-7. C5b-7 is lipophilic, resembles an integral membrane protein, and serves as an anchor for the late complement components, C8 and C9. Source: National Library of Medicine, MeSH 2006

LP16379-7 Complement C7
The complement system is a key part of the immune system and inflammatory response. The system has three pathways: 1) the classic pathway, 2) the alternative pathway, and 3) the lectin activation pathway. Complement C7 is involved in the alternate complement pathway and one of the late activation complement proteins along with C5, C6, C8, and C9. Patients with deficiencies of the late complement proteins are unable to form the membrane attack complex (MAC), the end result of the complement activation cascade. Patients with C7 deficiency have increased susceptibility to neisserial infections and some have developed systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), scleroderma, and pyoderma gangrenosum. Complement tests measure either the quantity or the activity (function) of complement proteins. In some cases, complement proteins are present but not functional, in which case a functional assay is used to detect the deficiency. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Complement C7:MCnc:Pt:Ser/Plas:Qn:
Long Common Name: Complement C7 [Mass/volume] in Serum or Plasma
Short Name: C7 SerPl-mCnc
Display Name: Complement C7 [Mass/Vol]
Consumer Name Alpha Get Info: Complement C7, Blood

Part Model Get Info

Component
Complement C7
LP16379-7
- Analyte
  Complement C7
  LP16379-7
  - Component Numerator
    Complement C7
    LP16379-7
    - Component Numerator Core
      Complement C7
      LP16379-7
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: HEM/BC
Type: Laboratory
First Released: Version 1.0
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 12320

Language Variants Get Info

Tag	Language	Translation
ar-JO	Arabic (Jordan)	المتمم C7 Synonyms: المتمم C7
cs-CZ	Czech (Czechia)	Komplement C7:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GR	Greek (Greece)	Συμπλήρωμα C7:MCnc:Pt:Ορός/Πλάσμα:Qn: Synonyms: HEM/BC MCnc Pt Qn Ορός Ορός/Πλάσμα Πλάσμα Συμπλήρωμα C7
es-AR	Spanish (Argentina)	fracción C7 del complemento:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ES	Spanish (Spain)	Complemento C7:Concentración de masa:Punto temporal:Suero o Plasma:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Complemento C7:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE	Estonian (Estonia)	Komplemendi komponent C7:MCnc:Pt:S/P:Qn: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA	French (Canada)	Complément C7:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR	French (France)	Complément C7:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE	French (Belgium)	Complément C7:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT	Italian (Italy)	Complemento C7:MCnc:Pt:Siero/Plasma:Qn: Synonyms: Concentrazione di Massa Ematologia (coagulazione) conta differenziale Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR	Korean (Korea, Republic Of)	도움체 C7:질량농도:검사시점:혈청/혈장:정량:
nl-NL	Dutch (Netherlands)	complement C7:massa/volume:moment:serum of plasma:kwantitatief:
pl-PL	Polish (Poland)	Dopełniacz C7:stężenie masowe:punkt w czasie:surowica lub osocze:ilościowy: Synonyms: Składowa C7 dopełniacza
pt-BR	Portuguese (Brazil)	Complemento C7:MCnc:Pt:Sor/Plas:Qn: Synonyms: ; Comp; Complmt; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; HEMATOLOGY/CELL COUNTS; HEMATOLOGY/CELL COUNTS
ru-RU	Russian (Russian Federation)	Комплемент C7:МассКонц:ТчкВрм:Сыв/Плаз:Колич: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Kompleman C7:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN	Chinese (China)	补体 C7:质量浓度:时间点:血清/血浆:定量型: Synonyms: 可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间水平;浓度;质量浓度(单位体积) 血液学/细胞计数;血液学与细胞计数血清或血浆

Example Units

Unit	Source
mg/L	Example UCUM Units
mg/L	eCHN

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.