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Part Description

LP16444-9   Hemoglobin Lepore
Hemoglobin Lepore syndrome or Hb Lepore syndrome (Hb Lepore) is typically an asymptomatic hemoglobinopathy, which is caused by an autosomal recessive genetic mutation. The Hb Lepore variant, consisting of two normal alpha globin chains (HBA) and two deltabeta globin fusion chains which occurs due to a "crossover" between the delta (HBD) and beta globin (HBB) gene loci during meiosis.

The homozygous state for Hb Lepore is rare. Patients of Balkan descent tend to have the most severe presentation of symptoms including severe anemia during the first five years of life. They also presented with significant splenomegaly, hepatomegaly, and skeletal abnormalities identical to those of homozygous beta-thalassemia. The amount of Hb Lepore in the patients blood ranged from 8 to 30 %, the remainder being fetal hemoglobin (Hb F) which is present in minute quantities (typically<1 percent) in the red blood cells of adults. Known as F- cells they are present in a small proportion of overall RBCs.

Heterozygous Hb Lepore is similar to beta-thalassemia major, however the clinical course is variable. Patients with this condition typically present with severe anemia during the first two years of life. The heterozygote form is mildly anemic (Hb 11-13 g/dl) but presents with a significant hypochromia (deficiency of hemoglobin in the red blood cells) and microcytosis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LOINC Names Get Info

Fully-Specified Name
Hemoglobin Lepore:PrThr:Pt:Bld:Ord:Electrophoresis pH 8.9
Long Common Name
Hemoglobin Lepore [Presence] in Blood by Electrophoresis alkaline (pH 8.9)
Short Name
Hgb Lepore Bld Ql Elph Alk
Display Name
Hemoglobin Lepore Elph pH 8.9 Ql (Bld)
Consumer Name Alpha Get Info
Hemoglobin lepore, Blood

Part Model Get Info

  • Component
    Hemoglobin Lepore
    LP16444-9
    • Analyte
      Hemoglobin Lepore
      LP16444-9
      • Component Numerator
        Hemoglobin Lepore
        LP16444-9
        • Component Numerator Core
          Hemoglobin Lepore
          LP16444-9
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Bld
    LP7057-5
    • System Core
      Bld
      LP7057-5
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Electrophoresis pH 8.9
    LP6249-9

Basic Attributes

Class
HEM/BC
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.56 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Observation

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Hemoglobin Lepore:Přítomnost nebo práh:Časový bod:Krev:Ordinální:Elektroforéza v alkalickém prostředí (pH 8,9)
el-GRGreek (Greece)Αιμοσφαιρίνη Lepore:PrThr:Pt:Αίμα:Ord:Ηλεκτροφόρηση pH 8,9
Synonyms: HEM/BC Ord PrThr Pt Αίμα Αιμοσφαιρίνη Αιμοσφαιρίνη Lepore Ηλεκτροφόρηση Ηλεκτροφόρηση pH 8,9
es-ARSpanish (Argentina)hemoglobima Lepore:concentración arbitraria:punto en el tiempo:sangre:ordinal:electroforesis pH 8,9
es-ESSpanish (Spain)Hemoglobina Lepore:PrThr:Punto temporal:Sangre:Ord:Electroforesis alcalina (ph8.9)
es-MXSpanish (Mexico)Lepore de hemoglobina:Presencia o umbral:Punto temporal:Sangre:Ordinal:Electroforesis alcalina (pH 8,9)
fr-CAFrench (Canada)Hémoglobine Lepore:Présence-Seuil:Temps ponctuel:Sang:Ordinal:Électrophorèse à pH 8,9
fr-FRFrench (France)Hémoglobine Lepore:Présence/Seuil:Ponctuel:Sang:Qualitatif:Électrophorèse pH 8.9
fr-BEFrench (Belgium)Hémoglobine Lepore:PrThr:Temps ponctuel:Sang:Ordinal:Électrophorèse à pH 8,9
Synonyms: Hb Hb Lepore
it-ITItalian (Italy)Emoglobina Lepore:PrThr:Pt:Sangue:Ord:Elettroforesi pH 8,9
Synonyms: Elettroforesi alcalina (pH 8,9) Ematologia (coagulazione) conta differenziale Presenza o Soglia Punto nel tempo (episodio) Sangue
ko-KRKorean (Korea, Republic Of)르포르 혈색소:임의농도:검사시점:전혈:순위척도:전기영동 pH 8.9
nl-NLDutch (Netherlands)hemoglobine Lepore:aanwezigheid:moment:bloed:ordinaal:elektroforese pH 8.9
pl-PLPolish (Poland)Hemoglobina Lepore:granica wykrywalności:punkt w czasie:krew:uporządkowany:elektroforeza zasadowa (pH=8, 9)
pt-BRPortuguese (Brazil)Hemoglobina Lepore:ACnc:Pt:SgTotal:Ord:Eletroforese pH 8.9
Synonyms: ; Hgb Lepore; Hb; Haemoglobin; Arbitrary concentration; Point in time; Random; Blood; WB; Whole blood; Ql; Ordinal; QL; Qualitative; Qual; Screen; Elph Alk; Elp; Elect; Electrophrs; Electrophhrs; Electr; Elec; Ep; Electro; HEMATOLOGY/CELL COUNTS; HEMATOLOGY/CELL COUNTS
tr-TRTurkish (Turkey)Hemoglobin Lepore:MevcEşik:Zmlı:Kan:Srl:Elektroforez pH 8.9
Synonyms: Mevcut
zh-CNChinese (China)血红蛋白 Lepore:存在情况或阈值:时间点:全血:序数型:电泳 pH 8.9
Synonyms: Hgb Lepore 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 氧血红蛋白;血红朊;血红素;血色素 电泳(pH 8.9);碱性电泳;碱性电泳 (pH 8.9);碱性电泳 pH 8.9 电泳分析;电泳分析方法;电泳分析类实验室方法;电泳分析类方法;电泳分析类检验方法;电泳方法;电泳类实验室方法;电泳类方法;电泳类检验方法 血;血液 血液学/细胞计数;血液学与细胞计数

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=4605-2