46082-4
Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
Active
Part Description
LP14239-5 Influenza virus A
Influenza viruses, from the family Orthomyxoviridae, are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C are medically relevant to humans. Aquatic birds harboring avian IAV are the likely natural reservoir for all known IAV subtypes and are probably the original source of all human pandemic IAV strains. IAV maintained in wild birds have been associated with stable host switch events to novel hosts, including most often to domestic poultry but also to horses, swine, toothed whales and humans. The influenza virus life cycle begins with the binding of viral HA to host cell receptors. Endocytosis and HA-mediated fusion of the viral and cellular membranes occurs. Viral ribonucleoprotein complexes are released into the cytoplasm, travel to the nucleus, then are replicated and transcribed by the viral polymerase complex. The new viruses are formed and bud when the newly formed ribonucleicprotein complexes and structural proteins reach the plasma membrane. Further research is needed to better understand how IAVs switch hosts and the viral genetic changes that underlie human adaptation. IAV causes respiratory infections in humans ranging from asymptomatic to fatal. Pandemics are attributed to "novel" viruses which possess a viral hemagglutinin (HA) to which humans do not have immunity. PMID: 20542248 ] PMID: 25812763
Influenza viruses A and B are single-stranded RNA enveloped viruses belonging to the Orthomyxoviridae family. The symptoms of infection of Influenza A and B include fever, cough, sore throat, rhinorrhea, nasal congestion, headache, myalgia and malaise. Some patients may experience gastrointestinal symptoms including watery diarrhea, vomiting and abdominal pain. The influenza viruses spread rapidly in enclosed spaces with a documented rate of infection of 70% following a common source of exposure. Infection occurs in the respiratory epithelium in both the upper and lower respiratory tract, and the virus can be found in many specimen types, including nasal aspirates, nasal or nasopharyngeal swabs, throat swabs, sputum and tracheal aspirates. When infection rates reach epidemic proportions, hospitalization of children and elderly patients rises as does the mortality rates of elderly patients.(Manual of Clinical Microbiology, 11th edition, James H. Jorgensen; Karen C. Carroll; Guido Funke; Michael A Pfaller; Marie Louise Landry; Sandra S. Richter; David W. Warnock)
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Influenza virus A Ag
- Property
- PrThr
- Time
- Pt
- System
- Nph
- Scale
- Ord
- Method
- IA
Additional Names
- Short Name
- FLUAV Ag Nph Ql IA
- Display Name
- FLUAV Ag IA Ql (Nph)
- Consumer Name Alpha Get Info
- Influenza A (Flu A) antigen, Nasopharynx
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.17
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 1935
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG32757-3 | Influenza virus |
| LG34020-4 | Influenza virus A Ag| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Influenza-Virus A Ag: |
| es-ES | Spanish (Spain) | Virus Influenza A Antígeno: |
| es-MX | Spanish (Mexico) | Virus de la influenza A Ag: |
| et-EE | Estonian (Estonia) | A-gripi viirus antigeen: Synonyms: Järgarvuline Juhuslik Ninaneel |
| fr-CA | French (Canada) | Virus de l'influenza A , Ag: |
| fr-FR | French (France) | Influenza virus A Ag: |
| fr-BE | French (Belgium) | Virus de l'influenza A Ag: Synonyms: Antigène FLU A virus FLU virus |
| it-IT | Italian (Italy) | Influenza A, virus , Ag: Synonyms: Immunoassay Microbiologia Presenza o Soglia Punto nel tempo (episodio) Rinofaringe Virus dell''influenza Virus dell''influenza A |
| nl-NL | Dutch (Netherlands) | Influenzavirus A Ag: Synonyms: antigeen IA |
| pl-PL | Polish (Poland) | Wirus grypy A Ag: Synonyms: Antygen wirusa grypy typ A Wirus grypy Wirus grypy typ A |
| pt-BR | Portuguese (Brazil) | Influenza vírus A Ag: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Грипп вирус А Аг: Synonyms: Носоглотка Порядковый Точка во времени; |
| tr-TR | Turkish (Turkey) | İnfluenza virüsü A Ag: Synonyms: Antijen İmmünölçüm, immünoassay Mevcut |
| uk-UA | Ukrainian (Ukraine) | Вірус грипу А, Антиген: Synonyms: Antigen; |
| zh-CN | Chinese (China) | 流感病毒 A 型 抗原: Synonyms: A 型 A 型抗原 A 型流感; |
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