4623-5
Hemoglobin S [Presence] in Blood by Electrophoresis alkaline (pH 8.9)
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Part Description
LP16455-5 Hemoglobin S
Hemoglobin S (HbS) is a variant form of hemoglobin found in people with sickle cell disease. The Hb S variant occurs primarily among people of African, Hispanic, and Mediterranean descent. Hb S has a variation in the β-chain gene that causes a change in the properties of hemoglobin, resulting in abnormal, rigid, sickling shape of red blood cells. Individuals with two copies of the Hb S variant have classic sickle cell disease (sickle cell anemia, HbSS). Individuals with one HbS variant and one normal hemoglobin, Hb A, have sickle cell trait (HbAS) and usually have no associated symptoms. Hemoglobins exhibit different migration patterns in alkaline versus acidic electrophoresis conditions. So a combination of 2 procedures can be used in tandem to identify the hemoglobin variants.
Source: Regenstrief LOINC
, Sickle-cell disease (Wikipedia)
Fully-Specified Name
- Component
- Hemoglobin S
- Property
- PrThr
- Time
- Pt
- System
- Bld
- Scale
- Ord
- Method
- Electrophoresis pH 8.9
Additional Names
- Long Common Name
- Hemoglobin S [Presence] in Blood by Electrophoresis alkaline (pH 8.9)
- Short Name
- Hgb S Bld Ql Elph Alk
- Display Name
- Hemoglobin S Elph pH 8.9 Ql (Bld)
- Consumer Name Alpha Get Info
- Hemoglobin S, Blood
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.56 (MIN)
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Observation
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Hämoglobin S: |
el-GR | Greek (Greece) | Αιμοσφαιρίνη S: Synonyms: PrThr S Αιμοσφαιρίνη Αιμοσφαιρίνη S |
es-AR | Spanish (Argentina) | hemoglobina S: |
es-ES | Spanish (Spain) | Hemoglobina S: |
es-MX | Spanish (Mexico) | Hemoglobina S: |
et-EE | Estonian (Estonia) | Hemoglobiin S: Synonyms: Järgarvuline Juhuslik Veri |
fr-CA | French (Canada) | Hémoglobine S: |
fr-FR | French (France) | Hémoglobine S: |
fr-BE | French (Belgium) | Hémoglobine S: Synonyms: Hb HbS |
it-IT | Italian (Italy) | Emoglobina S: Synonyms: Elettroforesi alcalina (pH 8,9) Ematologia (coagulazione) conta differenziale Presenza o Soglia Punto nel tempo (episodio) Sangue |
ko-KR | Korean (Korea, Republic Of) | 혈색소 S: |
nl-NL | Dutch (Netherlands) | hemoglobine S: |
pl-PL | Polish (Poland) | Hemoglobina S: |
pt-BR | Portuguese (Brazil) | Hemoglobina S: Synonyms: ; |
tr-TR | Turkish (Turkey) | Hemoglobin S: Synonyms: Mevcut |
zh-CN | Chinese (China) | 血红蛋白 S: Synonyms: HbS; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=4623-5
LOINC Copyright
Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://