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Term Description

The patient's allelic genotype (e.g. *1/*8) for the CYP2C9 gene allele. Testing may include the most common alleles of CYP2C9, such as *2, *6,*8,*11,*13,*15. The example answers provided with this code are a small representative of the CYP2C9 allelic genotypes. For a complete list of CYP2C9 alleles, see the The Human Cytochrome P450 (CYP) Allele Nomenclature Database (http://www.cypalleles.ki.se).

Part Description

LP417568-5   CYP2C9 gene allele
Cytochrome P450-2C9 (CYP2C9; [HGNC Gene ID: 2623]), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism 10-15% of drugs in current clinical use. Genetic variations in CYP2C9 can affect the response (i.e., efficacy or toxicity) to drugs metabolized by CYP2C9 and selection of alternative dosing or agents may be necessary in individuals with specific CYP2C9 genetic variations. PMID: 25099164 PMID: 21900891 See https://www.pharmgkb.org/gene/PA126 for more information and dosing guidelines for drugs impacted by CYP2C9 genetic variation. Source: Clinical Pharmacogenetics Implementation Consortium

LOINC Names Get Info

Fully-Specified Name
CYP2C9 gene allele:Geno:Pt:Bld/Tiss:Nom:Molgen
Long Common Name
CYP2C9 gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal
Short Name
CYP2C9 allele Geno Bld/T
Display Name
CYP2C9 gene allele genotype Molgen (Bld/Tiss)
Consumer Name Alpha Get Info
CYP2C9 gene allele genotype, Blood or tissue specimen

Part Model Get Info

  • Component
    CYP2C9 gene allele
    LP417568-5
    • Analyte
      CYP2C9 gene allele
      LP417568-5
      • Component Numerator
        CYP2C9 gene allele
        LP417568-5
        • Component Numerator Core
          CYP2C9 gene allele
          LP417568-5
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Geno
    LP345004-8
  • Time
    Pt
    LP6960-1
  • System
    Bld/Tiss
    LP7061-7
    • System Core
      Bld/Tiss
      LP7061-7
    • Super System
      NULL
       
  • Scale
    Nom
    LP7750-5
  • Method
    Molgen
    LP6404-0

Example Answer List: LL5510-4

Source: Regenstrief LOINC
AnswerCodeScoreAnswer ID
CYP2C9 *1/*2LA30670-6
CYP2C9 *1/*6LA30671-4
CYP2C9 *6/*11LA30672-2

Basic Attributes

Class
MOLPATH.PHARMG
Type
Laboratory
First Released
Version 2.19
Last Updated
Version 2.73 (MIN)
Change Reason
Release 2.68: CLASS: Updated to MOLPATH.PHARMG, the more representative LOINC Class for this concept.; COMPONENT: Updated Component to align with the LOINC term naming model for concepts used to report allelic genotypes (e.g. CYP2C9*1/*8), which was the original intent for this term.; Release 2.67: CLASS: Updated to MOLPATH.PHARMG, the more representative LOINC Class for this concept.; Previous Releases: Based on LOINC Committee review (June 2016), "targeted" was added to the Component to clarify that this test is looking for a specific set of mutations as described in the LOINC User Guide under the Molecular Genetics section.
Order vs. Observation
Both
Common Test Rank Get Info
9570

Member of these Panels

LOINCLong Common Name
54450-2CYP2C9 and VKORC1 panel - Blood or Tissue by Molecular genetics method
93196-4Warfarin response genotype panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Gen CYP2C9 alela:Genotyp:Časový bod:Krev/tkáň:Nominální:Molekulární genetika
de-ATGerman (Austria)Synonyms: CYP2C9 Genotyp.
el-GRGreek (Greece)Αλληλόμορφο γονιδίου CYP2C9:Geno:Pt:Αίμα/Ιστός:Nom:Μοριακή γενετική
Synonyms: Geno MOLPATH MOLPATH.PHARMG Nom Pt Αίμα Αίμα/Ιστός Αλληλόμορφο γονιδίου CYP2C9 Γονίδιο Γονίδιο CYP2C9 Ιστός Μοριακή γενετική
es-ESSpanish (Spain)Alelo del gen CYP2C9:Genotipo:Punto temporal:Sangre o tejido:Nom:Genética molecular
es-MXSpanish (Mexico)Alelo del gen CYP2C9:Genotipo:Punto temporal:Sangre o tejido:Nominal:Genética molecular
fr-FRFrench (France)CYP2C9 gène allèle:Génotype:Ponctuel:Sang/Tissu:Résultat nominal:Biologie moléculaire
it-ITItalian (Italy)CYP2C9, gene allele:Geno:Pt:Sangue/Tess:Nom:Molgen
Synonyms: Farmacogenomica Gene CYP2C9 Genetica molecolare Genotipo Patologia molecolare Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
nl-NLDutch (Netherlands)CYP2C9-allel:genotype:moment:bloed of weefsel:nominaal:moleculair genetisch onderzoek
Synonyms: CYP2C9 gen molgen
pl-PLPolish (Poland)CYP2C9 gen allel:genotyp:punkt w czasie:krew lub tkanka:skala nominalna:genetyka molekularna
Synonyms: Allel genu CYP2C9 diagnostyka molekularna Gen CYP2C9 wynik kategorialny
pt-BRPortuguese (Brazil)CYP2C9 análise de mutação genética:Ident:Pt:Sg/Tecido:Nom:Genética molecular
Synonyms: Cytochrome P450 2C9 Genotyping; CPC9; CYP2C; CYP2C10; CYPIIC9; Identity or presence; Point in time; Random; Bld/T; Tissue; Bld/T; Blood; WB; Whole blood; Nominal; PCR; Molecular genetics; Mut Anal; Mutations; MOLPATH.MUTATIONS; MOLPATH.MUTATIONS; Molecular pathology
zh-CNChinese (China)CYP2C9 基因等位基因:基因型:时间点:全血/组织:名义型:分子遗传学类实验室方法
Synonyms: CPC9;CYP2C;CYP2C10;CYPIIC9;细胞色素 P450 2C9 基因分型;细胞色素 P450 2C9 基因型分析;细胞色素 P450 2C9 基因型鉴定 全血或组织;血液/组织;血液或组织 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 血;血液 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=46724-1