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Term Description

This panel contains genotype results for warfarin dosing. As of 2019, CYP2C9, VKORC1, CYP4F2, and rs12777823 genotypes are used when available to help determine a patient's initial therapeutic warfarin dose. VKORC1 and CYP2C9 genotypes are the most important genetic determinants of warfarin dosing. Additionally, a genetic variation in the CYP4F2 gene, CYP4F2*3, as well as a variant near the CYP2C gene cluster, rs12777823, have been associated with influencing warfarin therapy.[NCBI Books: NBK84174] This panel is based on, but not limited in use to, the 2017 Update of the Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics-Guided Warfarin Dosing, which provides warfarin dosing recommendations for adults with and without African ancestry, and also for pediatric patients.https://cpicpgx.org/content/guideline/publication/warfarin/2017/warfarin.pdf

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINCNameR/O/CCardinalityExample UCUM Units
93196-4Warfarin response genotype panel - Blood or Tissue by Molecular genetics method
Indent46724-1CYP2C9 gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal
Indent79716-7CYP2C9 gene product metabolic activity interpretation in Blood or Tissue Qualitative by Molecular genetics method
Indent50722-8VKORC1 gene mutations found [Identifier] in Blood or Tissue by Targeted gene mutation analysis Nominal
Indent72507-7VKORC1 gene c.1173C>T [Presence] in Blood or Tissue by Molecular genetics method
Indent93198-010q23 g.94645745G>A [Genotype] in Blood or Tissue by Molecular genetics method Nominal
Indent93197-2CYP4F2 gene c.1297G>A [Genotype] in Blood or Tissue by Molecular genetics method Nominal
Indent79721-7CYP4F2 gene product metabolic activity interpretation in Blood or Tissue Qualitative by Molecular genetics method

LOINC Names Get Info

Fully-Specified Name
Warfarin response genotype panel:-:Pt:Bld/Tiss:-:Molgen
Long Common Name
Warfarin response genotype panel - Blood or Tissue by Molecular genetics method
Short Name
Warfarin genotype pnl Bld/T
Display Name
Warfarin response genotype panel Molgen (Bld/Tiss)
Consumer Name Alpha Get Info
Warfarin response genotype panel, Blood or tissue specimen

Part Model Get Info

  • Component
    Warfarin response genotype panel
    LP411048-4
    • Analyte
      Warfarin response genotype panel
      LP411048-4
      • Component Numerator
        Warfarin response genotype panel
        LP411048-4
        • Component Numerator Core
          Warfarin response genotype panel
          LP411048-4
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    -
    LP6769-6
  • Time
    Pt
    LP6960-1
  • System
    Bld/Tiss
    LP7061-7
    • System Core
      Bld/Tiss
      LP7061-7
    • Super System
      NULL
       
  • Scale
    -
    LP7747-1
  • Method
    Molgen
    LP6404-0

Basic Attributes

Class
PANEL.MOLPATH.PHARMG
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.67 (ADD)
Order vs. Observation
Order
Panel Type
Panel

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Warfarin odpověď genotyp panel:-:Časový bod:Krev/tkáň:-:Molekulární genetika
el-GRGreek (Greece)Πίνακας γονότυπου απόκρισης στη βαρφαρίνη:-:Pt:Αίμα/Ιστός:-:Μοριακή γενετική
Synonyms: - MOLPATH MOLPATH.PHARMG PANEL.MOLPATH PANEL.MOLPATH.PHARMG Pt Αίμα Αίμα/Ιστός Βαρφαρίνη Ιστός Μοριακή γενετική Πίνακας γονότυπου απόκρισης στη βαρφαρίνη
es-ESSpanish (Spain)Panel de genotipo de respuesta a warfarina:Propiedades mixtas (sólo paneles):Punto temporal:Sangre o tejido:-:Genética molecular
es-MXSpanish (Mexico)Panel de genotipo de respuesta a warfarina:-:Punto temporal:Sangre o tejido:-:Genética molecular
fr-FRFrench (France)Warfarine génotype panel:-:Ponctuel:Sang/Tissu:-:Biologie moléculaire
it-ITItalian (Italy)Warfarina, panel genotipo di risposta:-:Pt:Sangue/Tess:-:Molgen
Synonyms: Farmacogenomica Genetica molecolare Panel farmacogenomica Panel warfarina genotipo di risposta Patologia molecolare Punto nel tempo (episodio) Sangue Sangue o Tessuto Set di prescrizione patologia molecolare Tessuto & Strisci
zh-CNChinese (China)华法林反应基因型组套:-:时间点:全血/组织:-:分子遗传学类实验室方法
Synonyms: 全血或组织;血液/组织;血液或组织 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.分子病理学;分子病理学组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）.药物基因组学（药物基因体学、药物基因学、药物基因组）;分子病理学医嘱组类;医嘱组类.分子病理学;实验室医嘱组类.分子病理学 医嘱组.分子病理学;分子病理学组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）;分子病理学医嘱组类;医嘱组类.分子病理学;实验室医嘱组类.分子病理学 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 华法令;华法林;抗血凝性杀鼠剂;杀鼠灵;灭鼠灵 华法林（苄丙酮香豆素钠、杀鼠灵、华法林抗凝血剂、华法令）反应（反应性）组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目） 多重;多重型;多重标尺类型;多重精度类型 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 组 组合 组合医嘱 组合类 组套 血;血液

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93196-4
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/93196-4