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Part Description

LP15735-1   Methylmalonate
Methylmalonate (methylmalonic acid) is measured as a second-tier assay when abnormal propionyl carnitine or methionine concentrations are identified in a primary newborn screening. Methylmalonic acidemia (MMA) and propionic acidemia (PA) are defects of propionate metabolism caused by deficiencies in methylmalonyl-CoA mutase and propionyl-CoA carboxylase, respectively. The clinical phenotype of both conditions includes vomiting, hypotonia, lethargy, apnea, hypothermia, and coma. The biochemical phenotype for MMA includes elevated methylmalonic acid, propionyl carnitine and methylcitric acid, while patients with PA have elevated propionyl carnitine and methylcitric acid with normal methylmalonic acid concentrations as the enzymatic defect is upstream of methylmalonic-CoA mutase. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Methylmalonate:SRat:24H:Urine:Qn:
Long Common Name
Methylmalonate [Moles/time] in 24 hour Urine
Short Name
Methylmalonate 24h Ur-sRate
Display Name
Methylmalonate (24H U) [Moles/Time]
Consumer Name Alpha Get Info
Methylmalonate, Urine

Part Model Get Info

  • Component
    Methylmalonate
    LP15735-1
    • Analyte
      Methylmalonate
      LP15735-1
      • Component Numerator
        Methylmalonate
        LP15735-1
        • Component Numerator Core
          Methylmalonate
          LP15735-1
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    SRat
    LP6867-8
  • Time
    24H
    LP6924-7
  • System
    Urine
    LP7681-2
    • System Core
      Urine
      LP7681-2
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.19
Last Updated
Version 2.70 (MIN)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Methylmalonát:Látkový tok:24 hodin:Moč:Kvantitativní:
de-DEGerman (Germany)Methylmalonat:Stoffmengenrate:24 Stunden:Urin:Quantitativ:
Synonyms: Methylmalonsäure
el-GRGreek (Greece)Μεθύλομαλονικό οξύ:SRat:24H:Ούρα:Qn:
Synonyms: 24H CHEM Qn SRat Μεθύλομαλονικό οξύ Ούρα
es-ESSpanish (Spain)Metilmalonato:Indice de susbtancia:24 horas:Orina:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Malonato de metilo:Tasa de sustancia:24H:Orina:Cuantitativo:
et-EEEstonian (Estonia)Metüülmalonaat:SRat:24 tunni:U:Qn:
Synonyms: Aine määr Kvantitatiivne Uriin
fr-CAFrench (Canada)Méthylmalonate:Débit de substance:24 h:Urine:Quantitatif:
fr-FRFrench (France)Méthylmalonate:Moles/Temps:24H:Urine:Numérique:
fr-BEFrench (Belgium)Méthylmalonate:Débit de substance:24 h:Urine:Quantitatif:
it-ITItalian (Italy)Metilmalonato:SRat:24h:Urine:Qn:
Synonyms: 24 Ore Chimica Tasso di sostanza
nl-NLDutch (Netherlands)methylmalonaat:mol/tijd:24 uur:urine:kwantitatief:
Synonyms: 24U
pt-BRPortuguese (Brazil)Metilmalonato:SRat:24H:Urina:Qn:
Synonyms: MMA; Methylmalonic acid; sRate; Substance rate; 1 day; 24 hours; 24HR; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; Chemistry
ru-RURussian (Russian Federation)Метилмалонат:МольРасх:24 часа:Моча:Колич:
Synonyms: Количественный Молярная скорость;Молярный расход
tr-TRTurkish (Turkey)Metilmalonat:SubHz:24Sa:İdrar:Kant:
zh-CNChinese (China)甲基丙二酸:物质的量速率:24小时:尿液:定量型:
Synonyms: 1天;1日;24.0小时;一天;一日;二十四个小时;二十四小时 MMA;丙二酸二甲酯;甲基丙二酸盐;甲基丙二酸盐/酯;甲基丙二酸酯 克分子速率;克分子速率(单位时间);摩尔速率;摩尔速率(单位时间);物质的量速率(单位时间) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉

Example Units

UnitSource
nmol/(24.h)Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=47091-4