Version 2.78

Term Description

This test is intended to be used as a primary screening test for the diagnosis of infection with Cytomegalovirus (CMV). This test has been approved by the FDA for the screening of donors of human cells, tissues and tissue-based products. A Positive result is indicative of an infection with CMV, and may be used to disqualify a potential cell or tissue donor. This test is not intended to be used for routine clinical diagnostic testing. This test is required for all donors of "leukocyte-rich" human cells, tissues and tissue-based products
Source: Regenstrief LOINC

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Component
Cytomegalovirus Ab
Property
PrThr
Time
Pt
System
Ser^Donor
Scale
Ord
Method
HA

Additional Names

Short Name
CMV Ab Ser Donr Ql HA
Display Name
CMV Ab HA Ql (S donor)
Consumer Name Alpha Get Info
Cytomegalovirus (CMV) antibody, Donor Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.19
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
54037-7 HEDIS 2009 panel
57820-3 HEDIS 2010 panel
60442-1 HEDIS 2011 panel
67767-4 HEDIS 2012 panel
72199-3 HEDIS 2013 panel
74234-6 HEDIS 2014 Value Sets
75868-0 HEDIS 2015 Value Sets
79544-3 HEDIS 2016 Value Sets
82955-6 HEDIS 2017 Value Sets
87625-0 HEDIS 2018 Value Sets

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Cytomegalie-Virus Ak:Nachweis oder Schwellenwert:Zeitpunkt:Serum^Donor:Ordinal:Hämagglutinationstest
Synonyms: CMV
es-ES Spanish (Spain) Citomegalovirus Anticuerpos:PrThr:Punto temporal:Suero^donante:Ord:Hemaglutinacion
es-MX Spanish (Mexico) Citomegalovirus Ab:Presencia o umbral:Punto temporal:Ser ^ Donante:Ordinal:Hemaglutinación
et-EE Estonian (Estonia) Tsütomegaloviirus antikehad:PrThr:Pt:S^doonor:Ord:HA
Synonyms: Hemaglutinatsioon Järgarvuline Juhuslik Seerum
fr-CA French (Canada) Cytomégalovirus, Ac:Présence-Seuil:Temps ponctuel:Sérum^Donneur:Ordinal:Hémagglutination
fr-FR French (France) Cytomégalovirus Ac:Présence/Seuil:Ponctuel:Sérum du donneur:Qualitatif:Hémagglutination
fr-BE French (Belgium) Cytomégalovirus Ac:PrThr:Temps ponctuel:Sérum^Donneur:Ordinal:Hémagglutination
Synonyms: Anticorps CMV HA
it-IT Italian (Italy) Citomegalovirus Ab:PrThr:Pt:Siero^donatore:Ord:HA
Synonyms: anticorpo Emoagglutinazione Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero
nl-NL Dutch (Netherlands) Cytomegalovirus As:aanwezigheid:moment:serum^donor:ordinaal:hemagglutinatie
Synonyms: antistof; antilichaam
pl-PL Polish (Poland) Wirus cytomegalii Ab:granica wykrywalności:punkt w czasie:surowica^dawca:półilościowy:hemaglutynacja
Synonyms: Cytomegalowirus Przecwciała do cytomegalowirusa
pt-BR Portuguese (Brazil) Citomegalovírus Ac:ACnc:Pt:Soro^doador:Ord:Hemaglutinação
Synonyms: ; CMV; Cytomgal; Cytomegalo virus; Arbitrary concentration; Point in time; Random; Serum; SR; Donr; Ql; Ordinal; QL; Qualitative; Qual; Screen; IHA; Hemagglutination; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
tr-TR Turkish (Turkey) Cytomegalovirus Ab:MevcEşik:Zmlı:Ser^verici:Srl:HA
Synonyms: Ak Mevcut
zh-CN Chinese (China) 巨细胞病毒 抗体:存在情况或阈值:时间点:血清^供体:序数型:红细胞凝集试验法
Synonyms: Ab;自身抗体 CMV Ab CMV 抗体 CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒 供血者;捐献者;捐赠者;给予体;给体;超系统 - 供体 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 巨细胞病毒 Ab 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 时刻;随机;随意;瞬间 红细胞凝集法;红细胞凝集试验;红血球凝聚;血凝反应;血凝集;血凝集作用;血球凝集作用;血细胞凝集;血细胞凝集作用;血细胞凝集试验 血清^捐赠者

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=47363-7