47363-7
Cytomegalovirus Ab [Presence] in Serum from Donor by Hemagglutination
Active
Term Description
This test is intended to be used as a primary screening test for the diagnosis of infection with Cytomegalovirus (CMV). This test has been approved by the FDA for the screening of donors of human cells, tissues and tissue-based products. A Positive result is indicative of an infection with CMV, and may be used to disqualify a potential cell or tissue donor. This test is not intended to be used for routine clinical diagnostic testing. This test is required for all donors of "leukocyte-rich" human cells, tissues and tissue-based products
Source: Regenstrief LOINC
Part Description
LP14255-1 Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Cytomegalovirus Ab
- Property
- PrThr
- Time
- Pt
- System
- Ser^Donor
- Scale
- Ord
- Method
- HA
Additional Names
- Short Name
- CMV Ab Ser Donr Ql HA
- Display Name
- CMV Ab HA Ql (S donor)
- Consumer Name Alpha Get Info
- Cytomegalovirus (CMV) antibody, Donor Blood
Example Answer List: LL360-9
Source: Regenstrief InstituteAnswer | Code | Score | Answer ID |
---|---|---|---|
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.19
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
54037-7 | HEDIS 2009 panel |
57820-3 | HEDIS 2010 panel |
60442-1 | HEDIS 2011 panel |
67767-4 | HEDIS 2012 panel |
72199-3 | HEDIS 2013 panel |
74234-6 | HEDIS 2014 Value Sets |
75868-0 | HEDIS 2015 Value Sets |
79544-3 | HEDIS 2016 Value Sets |
82955-6 | HEDIS 2017 Value Sets |
87625-0 | HEDIS 2018 Value Sets |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Cytomegalie-Virus Ak: Synonyms: CMV |
es-ES | Spanish (Spain) | Citomegalovirus Anticuerpos: |
es-MX | Spanish (Mexico) | Citomegalovirus Ab: |
et-EE | Estonian (Estonia) | Tsütomegaloviirus antikehad: Synonyms: Hemaglutinatsioon Järgarvuline Juhuslik Seerum |
fr-CA | French (Canada) | Cytomégalovirus, Ac: |
fr-FR | French (France) | Cytomégalovirus Ac: |
fr-BE | French (Belgium) | Cytomégalovirus Ac: Synonyms: Anticorps CMV HA |
it-IT | Italian (Italy) | Citomegalovirus Ab: Synonyms: anticorpo Emoagglutinazione Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero |
nl-NL | Dutch (Netherlands) | Cytomegalovirus As: Synonyms: antistof; |
pl-PL | Polish (Poland) | Wirus cytomegalii Ab: Synonyms: Cytomegalowirus Przecwciała do cytomegalowirusa |
pt-BR | Portuguese (Brazil) | Citomegalovírus Ac: Synonyms: ; |
tr-TR | Turkish (Turkey) | Cytomegalovirus Ab: Synonyms: Ak Mevcut |
zh-CN | Chinese (China) | 巨细胞病毒 抗体: Synonyms: Ab; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=47363-7
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright