47400-7
Cocaine+Benzoylecgonine [Presence] in Urine by Confirmatory method
Active
Part Descriptions
LP36028-6 Cocaine+Benzoylecgonine
Cocaine is an alkaloid of Erythroxylon coca that is grown in the northern South American Andes, India, Africa and Java. It is used medicinally as a local anesthetic and vasoconstrictor in nasal surgery and to dilate pupils. Because cocaine is a powerful central nervous system stimulant it is among the most abused drugs. Cocaine abuse can lead to sudden death due to cardiotoxicity or the sequential development of hyperthermia, agitated delirium and respiratory arrest. Cocaine is metabolized in the liver to inactive benzoylecgonine (BZE). BZE is pharmacologically inactive and has a longer half-life than its parent drug cocaine. It is the substance most tested for when investigating suspected cocaine abuse. Cocaethylene (CE) is produced in the liver in the presence of ethanol and has been shown to have similar stimulatory effects as cocaine in animal studies.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition) Cocaethylene is toxic to the myocardium. PMID: 8761012
Source: Regenstrief LOINC
LP36028-6 Cocaine+Benzoylecgonine
Benzoylecgonine is the major metabolite of cocaine. It is a biological metabolite with a stable structure that resists hydrolysis, both in the body and in the environment. Benzoylecgonine remains in the body for a few days and is commonly used as a marker in drug tests. [PMCID:1929267] PMID: 27224254
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Cocaine+Benzoylecgonine
- Property
- PrThr
- Time
- Pt
- System
- Urine
- Scale
- Ord
- Method
- Confirm
Additional Names
- Short Name
- Cocaine+BZE Ur Ql Cfm
- Display Name
- Cocaine+Benzoylecgonine Confirm Ql (U)
- Consumer Name Alpha Get Info
- Cocaine+Benzoylecgonine, Urine
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.19
- Last Updated
- Version 2.56
- Change Reason
- The Property has been changed from ACnc to reflect new model for ordinal terms; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG50145-8 | Cocaine+Benzoylecgonine| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Cocaina+Benzoilecgonina: |
| es-MX | Spanish (Mexico) | Cocaína + Benzoilecgonina: |
| fr-CA | French (Canada) | Cocaïne+Benzoylecgonine: |
| fr-FR | French (France) | Cocaïne+benzoylecgonine: |
| fr-BE | French (Belgium) | Cocaïne+Benzoylecgonine: |
| it-IT | Italian (Italy) | Cocaina+Benzoilecgonina: Synonyms: Livelli farmacologici e tossicologia Presenza o Soglia Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | cocaïne + benzoylecgonine: |
| pt-BR | Portuguese (Brazil) | Cocaína+Benzoilecgonina: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Кокаин+Бензоилэкгонин: Synonyms: Порядковый Точка во времени; |
| tr-TR | Turkish (Turkey) | Kokain+Benzoilekgonin: Synonyms: Mevcut Teyid |
| zh-CN | Chinese (China) | 可卡因+苯甲酰芽子碱: Synonyms: C17H21NO4; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=47400-7
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright