Version 2.80

Part Description

LP15532-2   Dermatan sulfate
Dermatan sulfate is a derived disaccharide that accumulates in lysosomes, extracellular matrix, and body fluids of people with mucopolysaccharidoses (MPSs). MPSs are rare disorders caused by a deficiency of enzymes that break down glycosaminoglycans (GAGs). Symptoms of MPS vary due to which storage product accumulates and the level of enzymatic function or concentration that remains. Symptoms include musculoskeletal, airway, cardiac, and central nervous system disorders. Treatments include hematopoietic stem cell transplantation for the more critical forms of MPS and intravenous enzyme replacement therapy for the others. Treatment is most effective when it is initiated before irreversible tissue damage has occurred. Because MPS is so rare and the symptoms so variable, it is difficult to diagnose in its earliest stages. A solution to that problem is the development of newborn screening assays that can detect dermatan sulfate, though the levels in the dried blood spot samples do not appear to predict the severity of disease. The pattern of dermatan and heparan sulfate can help distinguish between the different MPSs. PMID: 23084433 Source: Regenstrief LOINC

Fully-Specified Name

Component
Dermatan sulfate
Property
PrThr
Time
Pt
System
Urine
Scale
Ord
Method

Additional Names

Long Common Name
Dermatan sulfate [Presence] in Urine
Short Name
Dermatan Sulfate Ur Ql
Display Name
Dermatan sulfate Ql (U)
Consumer Name Alpha Get Info
Dermatan sulfate, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.21
Last Updated
Version 2.56 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Θειική δερματάνη:PrThr:Pt:Ούρα:Ord:
Synonyms: PrThr Θειικά άλατα Θειική δερματάνη
es-ES Spanish (Spain) Dermatan sulfato:PrThr:Punto temporal:Orina:Ord:
es-MX Spanish (Mexico) Sulfato de dermatán:Presencia o umbral:Punto temporal:Orina:Ordinal:
et-EE Estonian (Estonia) Dermataansulfaat:PrThr:Pt:U:Ord:
Synonyms: Järgarvuline Juhuslik Uriin
fr-CA French (Canada) Dermatane sulfate:Présence-Seuil:Temps ponctuel:Urine:Ordinal:
fr-FR French (France) Dermatane sulfate:Présence/Seuil:Ponctuel:Urine:Qualitatif:
fr-BE French (Belgium) Dermatane-sulfate:PrThr:Temps ponctuel:Urine:Ordinal:
Synonyms: SO4
it-IT Italian (Italy) Dermatan solfato:PrThr:Pt:Urine:Ord:
Synonyms: Chimica Presenza o Soglia Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) dermatansulfaat:aanwezigheid:moment:urine:ordinaal:
pt-BR Portuguese (Brazil) Sulfato de dermatan:ACnc:Pt:Urina:Ord:
Synonyms: SO4-2; Sulf; SO4; Chondroitin B sulfate; Arbitrary concentration; Point in time; Random; Ur; UR; Urn; UA; Ql; Ordinal; QL; Qualitative; Qual; Screen; Dermatin; Chemistry
ru-RU Russian (Russian Federation) Дерматан сульфат:PrThr:ТчкВрм:Моча:Пор:
Synonyms: Дерматансульфат Порядковый Точка во времени;Момент
tr-TR Turkish (Turkey) Dermatan sülfat:MevcEşik:Zmlı:İdrar:Srl:
Synonyms: Mevcut
zh-CN Chinese (China) 硫酸皮肤素:存在情况或阈值:时间点:尿液:序数型:
Synonyms: SO4;SO4-2;Sulf;硫酸;硫酸根;硫酸盐;硫酸酯 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 尿;小便;下泉 时刻;随机;随意;瞬间 硫酸软骨素 B;软骨素 B 硫酸酯

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