47707-5

Methylmalonate/Urea [Molar ratio] in Amniotic fluid

Active

Part Description

LP15735-1 Methylmalonate
Methylmalonate (methylmalonic acid) is measured as a second-tier assay when abnormal propionyl carnitine or methionine concentrations are identified in a primary newborn screening. Methylmalonic acidemia (MMA) and propionic acidemia (PA) are defects of propionate metabolism caused by deficiencies in methylmalonyl-CoA mutase and propionyl-CoA carboxylase, respectively. The clinical phenotype of both conditions includes vomiting, hypotonia, lethargy, apnea, hypothermia, and coma. The biochemical phenotype for MMA includes elevated methylmalonic acid, propionyl carnitine and methylcitric acid, while patients with PA have elevated propionyl carnitine and methylcitric acid with normal methylmalonic acid concentrations as the enzymatic defect is upstream of methylmalonic-CoA mutase. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Methylmalonate/Urea:SRto:Pt:Amnio fld:Qn:
Long Common Name: Methylmalonate/Urea [Molar ratio] in Amniotic fluid
Short Name: Methylmalonate/Urea Amn-sRto
Display Name: Methylmalonate/Urea (Amn fld) [Molar ratio]
Consumer Name Alpha Get Info: Methylmalonate/Urea, Amniotic fluid

Part Model Get Info

Component
Methylmalonate/Urea
LP286530-3
- Analyte
  Methylmalonate/Urea
  LP286530-3
  - Component Numerator
    Methylmalonate
    LP15735-1
    - Component Numerator Core
      Methylmalonate
      LP15735-1
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Urea
    LP69843-8
    - Component Denominator Core
      Urea
      LP69843-8
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
SRto
LP6868-6
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Amnio fld
LP7000-5
- System Core
  Amnio fld
  LP7000-5
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.21
Last Updated: Version 2.70 (MIN)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Methylmalonát/močovina:Látkový poměr:Časový bod:Amniová tekutina:Kvantitativní:
el-GR	Greek (Greece)	Μεθύλομαλονικό οξύ/Ουρία:SRto:Pt:Αμνιακό υγρό:Qn: Synonyms: CHEM Pt Qn SRto Αμνιακό υγρό Μεθύλομαλονικό οξύ Ουρία
es-ES	Spanish (Spain)	Metilmalonato/Urea:Relacion de Sustancia:Punto temporal:Fluido Ammiótico:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Malonato de metilo / urea:Proporción de sustancia:Punto temporal:Líquido amniótico:Cuantitativo:
fr-CA	French (Canada)	Méthylmalonate/Urée:Ratio de substance:Temps ponctuel:Liquide amniotique:Quantitatif:
fr-FR	French (France)	Méthylmalonate/urée:Moles ratio:Ponctuel:Liquide amniotique:Numérique:
fr-BE	French (Belgium)	Méthylmalonate/Urée:Ratio de substance:Temps ponctuel:Liquide amniotique:Quantitatif:
it-IT	Italian (Italy)	Metilmalonato/Urea:Srto:Pt:Liquido amniotico:Qn: Synonyms: Chimica Liquido amniotico Punto nel tempo (episodio) Rapporto di sostanza
nl-NL	Dutch (Netherlands)	methylmalonaat/ureum:molaire verhouding:moment:vruchtwater:kwantitatief:
pt-BR	Portuguese (Brazil)	Metilmalonato/Uréia:SCrto:Pt:LiqAmni:Qn: Synonyms: MMA; Methylmalonic acid; sRto; Substance concentration ratio; Point in time; Random; Amn; Amniotic fluid; Amn fl; Amniotic flu; AF; Quantitative; QNT; Quant; Quan; Chemistry
ru-RU	Russian (Russian Federation)	Метилмалонат/Мочевина:МольОтн:ТчкВрм:Амниотич ждк:Колич: Synonyms: Амниотическая жидкость Количественный Мольная доля;Молярная доля;Отношение концентраций Точка во времени;Момент
tr-TR	Turkish (Turkey)	Metilmalonat/Üre:SOrn:Zmlı:Amniyon sv:Kant: Synonyms: Amniyon mayii SubsOranı
zh-CN	Chinese (China)	甲基丙二酸/尿素:物质的量比率:时间点:羊水:定量型: Synonyms: CO(NH2)2 CO(NH2)2;碳酰二胺;脲 MMA;丙二酸二甲酯;甲基丙二酸盐;甲基丙二酸盐/酯;甲基丙二酸酯化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值羊膜水;胎水

Example Units

Unit	Source
mmol/mmol	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.