47708-3

Methylmalonate/Urea [Molar ratio] in Serum or Plasma

Active

Part Description

LP15735-1 Methylmalonate
Methylmalonate (methylmalonic acid) is measured as a second-tier assay when abnormal propionyl carnitine or methionine concentrations are identified in a primary newborn screening. Methylmalonic acidemia (MMA) and propionic acidemia (PA) are defects of propionate metabolism caused by deficiencies in methylmalonyl-CoA mutase and propionyl-CoA carboxylase, respectively. The clinical phenotype of both conditions includes vomiting, hypotonia, lethargy, apnea, hypothermia, and coma. The biochemical phenotype for MMA includes elevated methylmalonic acid, propionyl carnitine and methylcitric acid, while patients with PA have elevated propionyl carnitine and methylcitric acid with normal methylmalonic acid concentrations as the enzymatic defect is upstream of methylmalonic-CoA mutase. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Methylmalonate/Urea:SRto:Pt:Ser/Plas:Qn:
Long Common Name: Methylmalonate/Urea [Molar ratio] in Serum or Plasma
Short Name: Methylmalonate/Urea SerPl-sRto
Display Name: Methylmalonate/Urea [Molar ratio]
Consumer Name Alpha Get Info: Methylmalonate/Urea, Blood

Part Model Get Info

Component
Methylmalonate/Urea
LP286530-3
- Analyte
  Methylmalonate/Urea
  LP286530-3
  - Component Numerator
    Methylmalonate
    LP15735-1
    - Component Numerator Core
      Methylmalonate
      LP15735-1
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Urea
    LP69843-8
    - Component Denominator Core
      Urea
      LP69843-8
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
SRto
LP6868-6
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.21
Last Updated: Version 2.70 (MIN)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Methylmalonát/močovina:Látkový poměr:Časový bod:Sérum/plazma:Kvantitativní:
el-GR	Greek (Greece)	Μεθύλομαλονικό οξύ/Ουρία:SRto:Pt:Ορός/Πλάσμα:Qn: Synonyms: CHEM Pt Qn SRto Μεθύλομαλονικό οξύ Ορός Ορός/Πλάσμα Ουρία Πλάσμα
es-ES	Spanish (Spain)	Metilmalonato/Urea:Relacion de Sustancia:Punto temporal:Suero o Plasma:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Malonato de metilo / urea:Proporción de sustancia:Punto temporal:Suero o Plasma:Cuantitativo:
fr-CA	French (Canada)	Méthylmalonate/Urée:Ratio de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR	French (France)	Méthylmalonate/urée:Moles ratio:Ponctuel:Sérum/Plasma:Numérique:
fr-BE	French (Belgium)	Méthylmalonate/Urée:Ratio de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT	Italian (Italy)	Metilmalonato/Urea:Srto:Pt:Siero/Plasma:Qn: Synonyms: Chimica Plasma Punto nel tempo (episodio) Rapporto di sostanza Siero Siero o Plasma
nl-NL	Dutch (Netherlands)	methylmalonaat/ureum:molaire verhouding:moment:serum of plasma:kwantitatief:
pt-BR	Portuguese (Brazil)	Metilmalonato/Uréia:SCrto:Pt:Sor/Plas:Qn: Synonyms: MMA; Methylmalonic acid; sRto; Substance concentration ratio; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Chemistry
ru-RU	Russian (Russian Federation)	Метилмалонат/Мочевина:МольОтн:ТчкВрм:Сыв/Плаз:Колич: Synonyms: Количественный Мольная доля;Молярная доля;Отношение концентраций Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Metilmalonat/Üre:SOrn:Zmlı:Ser/Plaz:Kant: Synonyms: SubsOranı
zh-CN	Chinese (China)	甲基丙二酸/尿素:物质的量比率:时间点:血清/血浆:定量型: Synonyms: CO(NH2)2 CO(NH2)2;碳酰二胺;脲 MMA;丙二酸二甲酯;甲基丙二酸盐;甲基丙二酸盐/酯;甲基丙二酸酯化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值血清或血浆

Example Units

Unit	Source
mmol/mmol	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=47708-3

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.