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Part Descriptions

LP15033-1   Lactate dehydrogenase
Lactate dehydrogenase (LDH) is an enzyme (EC 1.1.1.27) present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. As it can also catalyze the oxidation of hydroxybutyrate, it is occasionally called hydroxybutyrate dehydrogenase (HBD). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, D-lactate (Wikipedia)

LP15033-1   Lactate dehydrogenase
Lactate dehydrogenase (LDH, or also called LD) is an oxidoreductase (LD: EC 1.1.1.27) and is the most important clinically of several dehydrogenases occurring in human serum. LDH catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD. When disease, injury, or toxic material damages tissues, cells release LDH into the bloodstream. Since LDH is a fairly stable enzyme, it has been widely used to evaluate the presence of damage and toxicity of tissue and cells. LDH is cytoplasmic in its cellular location and in any one tissue is composed of one or two of five possible isoenzymes. While many of its clinical applications involve quantification of one or more specific serum isoenzymes, an estimate of total LDH is usually required. Lactate dehydrogenase catalyzes the reversible reaction: L-lactate + NAD <--> pyruvate + NADH. Testing methods either measure the increase in NADH produced in the lactate-to-pyruvate reaction or the decrease in NADH produced in the pyruvate-to-lactate reaction. PMID: 3882046. Reference ranges are highly method dependent. The pyruvate-to-lactate reaction is preferred theoretically because the equilibrium constant is large and the rate for any amount of enzyme is 2-3 times faster, thus smaller sample and shorter observation periods are needed. Disadvantages of the pyruvate-to-lactate reaction are loss of linearity as compared with the lactate-to-pyruvate reaction, and greater substrate inhibition of the enzyme. [Tietz Fourth Edition] Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Lactate dehydrogenase:CRat:24H:Urine:Qn:
Long Common Name
Lactate dehydrogenase [Enzymatic activity/time] in 24 hour Urine
Short Name
LDH 24h Ur-cRate
Display Name
LDH (24H U) [Catalytic activity/Time]
Consumer Name Alpha Get Info
Lactate Dehydrogenase (LDH), Urine

Part Model Get Info

  • Component
    Lactate dehydrogenase
    LP15033-1
    • Analyte
      Lactate dehydrogenase
      LP15033-1
      • Component Numerator
        Lactate dehydrogenase
        LP15033-1
        • Component Numerator Core
          Lactate dehydrogenase
          LP15033-1
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    CRat
    LP6799-3
  • Time
    24H
    LP6924-7
  • System
    Urine
    LP7681-2
    • System Core
      Urine
      LP7681-2
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.21
Last Updated
Version 2.70 (MIN)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Laktátdehydrogenáza:Tok katalytické aktivity:24 hodin:Moč:Kvantitativní:
de-DEGerman (Germany)Lactatdehydrogenase:Katalytische Rate:24 Stunden:Urin:Quantitativ:
Synonyms: LDH
el-GRGreek (Greece)Γαλακτική αφυδρογονάση:CRat:24H:Ούρα:Qn:
Synonyms: 24H CHEM CRat Qn Γαλακτική αφυδρογονάση Γαλακτικό οξύ Ούρα
es-ESSpanish (Spain)Lactato deshidrogenasa:Índice catalítico:24 horas:Orina:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Lactato deshidrogenasa:Tasa catalítica:24H:Orina:Cuantitativo:
et-EEEstonian (Estonia)Laktaadi dehüdrogenaas:CRat:24 tunni:U:Qn:
Synonyms: Kvantitatiivne Uriin
fr-CAFrench (Canada)Lactate déshydrogénase:Taux catalytique:24 h:Urine:Quantitatif:
fr-FRFrench (France)Lactate déshydrogénase:Catalytique/Temps:24H:Urine:Numérique:
fr-BEFrench (Belgium)Lactate déshydrogénase:Taux catalytique:24 h:Urine:Quantitatif:
Synonyms: LDH
it-ITItalian (Italy)Lattato deidrogenasi:CRat:24h:Urine:Qn:
Synonyms: 24 Ore Chimica Tasso Catalitico
nl-NLDutch (Netherlands)lactaatdehydrogenase:enzymatische activiteit/tijd:24 uur:urine:kwantitatief:
Synonyms: 24U
pl-PLPolish (Poland)Dehydrogenaza mleczanowa:wskaźnik szybkości katalitycznej:24h:mocz:ilościowy:
Synonyms: 24 godziny
pt-BRPortuguese (Brazil)Desidrogenase Láctica:CRat:24H:Urina:Qn:
Synonyms: ; LDH; L.D.H; Lactic acid dehydrogenase; LD; L-lactate dehydrogenase; Lact; 2-hydroxy-propionic acid; 2-hydroxy-propionate; cRate; Catalytic Rate; 1 day; 24 hours; 24HR; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; Dehydrog; Dehyrdogenase; Chemistry
ru-RURussian (Russian Federation)Лактатдегидрогеназа:КаталСкор:24 часа:Моча:Колич:
Synonyms: Каталитическая скорость Количественный
tr-TRTurkish (Turkey)Laktat dehidrojenaz:KtlHız:24Sa:İdrar:Kant:
zh-CNChinese (China)乳酸脱氢酶:催化速率:24小时:尿液:定量型:
Synonyms: 1天;1日;24.0小时;一天;一日;二十四个小时;二十四小时 2-羟基-丙酸;Lact;L-乳酸 L.D.H;LD;LDH;L-乳酸脱氢酶 催化速率(单位时间) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 去氢酶 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉

Example Units

UnitSource
U/(24.h)Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=47863-6