Version 2.80

Part Description

LP15821-9   Propionyl CO-A carboxylase
Propionyl-CoA carboxylase catalyses the carboxylation reaction of propionyl CoA. The product of the reaction is (S)-methylmalonyl CoA. Propionyl CoA is the end product of metabolism of odd-chain fatty acids, and is also a metabolite of most methyl-branched fatty acids. It is also the main metabolite of valine, and together with acetyl-CoA, is a metabolite of isoleucine, as well as a methionine metabolite. Propionyl-CoA is thus of great importance as a glucose precursor. (S)-Methylmalonyl-CoA is not directly utilizable by animals; it is acted on by a racemase to give (R)-methylmalonyl-CoA. The latter is converted by methylmalonyl-CoA mutase (one of a very few Vitamin B12 dependent enzymes) to give succinyl-CoA. The latter is converted to oxaloacetate and then malate in the Krebs cycle. Export of malate into the cytosol leads to formation of oxaloacetate, phosphoenol pyruvate, and other gluconeogenic intermediates.

A deficiency is associated with propionic acidemia. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Wikipedia

Fully-Specified Name

Component
Propionyl CO-A carboxylase
Property
CCnt
Time
Pt
System
Placenta
Scale
Qn
Method

Additional Names

Long Common Name
Propionyl CoA Carboxylase [Enzymatic activity/mass] in Placenta
Short Name
PCCA Placenta-cCnt
Display Name
Propionyl CoA Carboxylase (Placenta) [Catalytic activity/Mass]
Consumer Name Alpha Get Info
Propionyl coA carboxylase, Placenta

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.21
Last Updated
Version 2.70 (MIN)
Change Reason
Changed System from Placent to Placenta so that all terms with a System of Placenta are consistent.
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Καρβοξυλάση προπιονυλοσυνένζυμου Α:CCnt:Pt:Πλακούντας:Qn:
Synonyms: A CCnt Καρβοξυλάση προπιονυλοσυνένζυμου Α
es-ES Spanish (Spain) Propionil CoA carboxilasa:Contenido catalítico:Punto temporal:Placenta:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Propionil CO-A carboxilasa:Contenido catalítico:Punto temporal:Placenta:Cuantitativo:
fr-CA French (Canada) Propionyl-CoA carboxylase:Contenu catalytique:Temps ponctuel:Placenta:Quantitatif:
fr-FR French (France) Propionyl CoA carboxylase:Catalytique/Masse:Ponctuel:Placenta:Numérique:
it-IT Italian (Italy) Propionil CO-A carbossilasi:CCnt:Pt:Placenta:Qn:
Synonyms: Chimica Contenuto Catalitico Propionil CoA Carbossilasi Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) propionyl CO-A carboxylase:enzymatische activiteit/massa:moment:placenta:kwantitatief:
pt-BR Portuguese (Brazil) Propionil CO-A carboxilase:CCnt:Pt:Placenta:Qn:
Synonyms: ; PCC; Catalytic Content; Point in time; Random; Placenta; Plc; Quantitative; QNT; Quant; Quan; Chemistry
ru-RU Russian (Russian Federation) Пропионил CoA карбоксилаза:КаталСод:ТчкВрм:Плацента:Колич:
Synonyms: Каталитическое содержание Количественный Пропионил КоА карбоксилаза Точка во времени;Момент
zh-CN Chinese (China) 丙酰 CoA 羧化酶:催化含量:时间点:胎盘:定量型:
Synonyms: A 型 PCC;丙酰辅酶 A 羧化酶 催化含量(单位质量);单位质量的酶单位数 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 胎座;胎痤;胞衣

Example Units

Unit Source
nmol/min/mg{protein} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=47876-8