48159-8
Hepatitis C virus Ab Signal/Cutoff in Serum or Plasma by Immunoassay
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Part Descriptions
LP14400-3 Hepatitis C virus
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630]
Source: Regenstrief LOINC, NCBI Books: NBK1630
LP62989-6 Hepatitis C virus Ab Signal/Cutoff
Signal-to-cut-off ratios are calculated by dividing the optical density (OD) value of the sample being tested by the OD value of the assay cut-off for that run.
Source: Regenstrief Institute
Fully-Specified Name
- Component
- Hepatitis C virus Ab Signal/Cutoff
- Property
- RelACnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
- IA
Additional Names
- Short Name
- HCV Ab s/co SerPl IA
- Display Name
- HCV Ab Signal/Cutoff IA [Rel units/Vol]
- Consumer Name Alpha Get Info
- Hepatitis C virus (HCV)/Cutoff, Blood
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.21
- Last Updated
- Version 2.73
- Change Reason
- Changed Order_Obs from Observation Only to fit current order use cases.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 443
Member of these Panels
LOINC | Long Common Name |
---|---|
24363-4 | Acute hepatitis 2000 panel - Serum |
75886-2 | HCV antibody screening - Meaningful Use set |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG32754-0 | Hepatitis C virus |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Hepatitis-C-Virus Antikörper-Signal/Cutoff: Synonyms: Hepacivirus C; |
es-ES | Spanish (Spain) | Virus Hepatitis C Señal de anticuerpos/Punto de corte: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Señal / corte de Ab del virus de la hepatitis C: |
fr-CA | French (Canada) | Virus de l'hépatite C, signal Ac/Seuil décisionnel: |
fr-FR | French (France) | Hépatite C virus Ac signal/cutoff: |
fr-BE | French (Belgium) | Virus de l'hépatite C Signal anticorps/Seuil décisionnel: Synonyms: Anticorps HCV |
it-IT | Italian (Italy) | Epatite C, virus Ab Segnale/Cutoff: Synonyms: anticorpo Concentrazine Arbitraria Relativa Cut-off Immunoassay Microbiologia Plasma Punto nel tempo (episodio) segnale anticorpale Siero Siero o Plasma Virus dell''epatite C |
nl-NL | Dutch (Netherlands) | Hepatitis C-virus As-signaal/afkapwaarde: Synonyms: antistof; |
pl-PL | Polish (Poland) | Wirus zapalenia wątroby typu C Ab sygnałowe/punkt odcięcia: Synonyms: Przeciwciała do wirusa zapalenia wątroby typu C Przeciwciała do wirusa zapalenia wątroby typu C sygnał Przeciwciała do wirusa zapalenia wątroby typu C sygnał/wartość odcięcia |
pt-BR | Portuguese (Brazil) | Hepatite C vírus Ac Sinal/Cutoff: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Гепатита С вирус Ат сигнал/Порог: Synonyms: Антитело Количественный Относительная произвольная концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | Hepatit C virüsü Ab sinyal/Kestirim: Synonyms: Ak Ak sinyal İmmünölçüm, immünoassay |
uk-UA | Ukrainian (Ukraine) | Вірус Гепатиту С Антитіла Сигнал/Порогове значення: Synonyms: ABS; |
zh-CN | Chinese (China) | 丙型肝炎病毒 抗体信号值/截止点: Synonyms: Ab; |
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