LOINC
Version 2.72

48310-7Influenza virus A [Presence] in Specimen by Organism specific cultureActive

Part Descriptions

LP14239-5   Influenza virus A
Influenza viruses, from the family Orthomyxoviridae, are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C are medically relevant to humans. Aquatic birds harboring avian IAV are the likely natural reservoir for all known IAV subtypes and are probably the original source of all human pandemic IAV strains. IAV maintained in wild birds have been associated with stable host switch events to novel hosts, including most often to domestic poultry but also to horses, swine, toothed whales and humans. The influenza virus life cycle begins with the binding of viral HA to host cell receptors. Endocytosis and HA-mediated fusion of the viral and cellular membranes occurs. Viral ribonucleoprotein complexes are released into the cytoplasm, travel to the nucleus, then are replicated and transcribed by the viral polymerase complex. The new viruses are formed and bud when the newly formed ribonucleicprotein complexes and structural proteins reach the plasma membrane. Further research is needed to better understand how IAVs switch hosts and the viral genetic changes that underlie human adaptation. IAV causes respiratory infections in humans ranging from asymptomatic to fatal. Pandemics are attributed to "novel" viruses which possess a viral hemagglutinin (HA) to which humans do not have immunity. [PMID:20542248] [PMID:25812763]
Influenza viruses A and B are single-stranded RNA enveloped viruses belonging to the Orthomyxoviridae family. The symptoms of infection of Influenza A and B include fever, cough, sore throat, rhinorrhea, nasal congestion, headache, myalgia and malaise. Some patients may experience gastrointestinal symptoms including watery diarrhea, vomiting and abdominal pain. The influenza viruses spread rapidly in enclosed spaces with a documented rate of infection of 70% following a common source of exposure. Infection occurs in the respiratory epithelium in both the upper and lower respiratory tract, and the virus can be found in many specimen types, including nasal aspirates, nasal or nasopharyngeal swabs, throat swabs, sputum and tracheal aspirates. When infection rates reach epidemic proportions, hospitalization of children and elderly patients rises as does the mortality rates of elderly patients.(Manual of Clinical Microbiology, 11th edition, James H. Jorgensen; Karen C. Carroll; Guido Funke; Michael A Pfaller; Marie Louise Landry; Sandra S. Richter; David W. Warnock) Source: Regenstrief LOINC

LP6429-7   Organism specific culture
An organism-specific culture contains nutrients that optimize the growth of a specific organism and inhibitors that prevent the growth of competing organisms. Source: Regenstrief LOINC

Fully-Specified Name

Component
Influenza virus A
Property
PrThr
Time
Pt
System
XXX
Scale
Ord
Method
Organism specific culture

Additional Names

Short Name
FLUAV Spec Ql Cult
Display Name
FLUAV Org specific cx Ql (Specimen)
Consumer Name Alpha
Influenza A (Flu A) culture, Specimen

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.21
Last Updated
Version 2.69
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
55101-0 Respiratory pathogens panel - Specimen by Organism specific culture

Member of these Groups

LG32757-3 Influenza virus

Language Variants Get Info

zh-CNChinese (China)
流感病毒 A 型:存在情况或阈值:时间点:XXX:序数型:微生物特异性培养
nl-NLDutch (Netherlands)
Influenzavirus A:aanwezigheid:moment:XXX:ordinaal:organisme-specifieke kweek
fr-BEFrench (Belgium)
Virus de l'influenza A:PrThr:Temps ponctuel:XXX:Ordinal:Culture spécifique de microorganisme
fr-CAFrench (Canada)
Virus de l'influenza A:Présence-Seuil:Temps ponctuel:XXX:Ordinal:Culture spécifique à un microorganisme
fr-FRFrench (France)
Influenza virus A:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:Culture spécifique
it-ITItalian (Italy)
Influenza A, virus:PrThr:Pt:XXX:Ord:Organismo, coltura specifica
pt-BRPortuguese (Brazil)
Influenza vírus A:ACnc:Pt:XXX:Ord:Cultura para microorganismo específico
ru-RURussian (Russian Federation)
Грипп вирус А:PrThr:ТчкВрм:XXX:Пор:Культура специфичного оранизма
es-MXSpanish (Mexico)
Virus de la influenza A:Presencia o umbral:Punto temporal:XXX:Ordinal:Cultivo específico del organismo
es-ESSpanish (Spain)
Virus Influenza A:PrThr:Punto temporal:XXX:Ord:Cultivos especíificos
tr-TRTurkish (Turkey)
İnfluenza virüsü A:MevcEşik:Zmlı:XXX:Srl:Etken spesifik kültür

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=48310-7