Version 2.78

Part Descriptions

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

LP40499-3   Alpha-1-Microglobulin
Alpha-1-microglobulin (also called protein HC or A1M) is a 31-kD, single-chain plasma glycoprotein that may be involved in regulation of the inflammatory process. The alpha-1-microglobulin/bikunin precursor gene (AMBP) codes for a precursor that splits into alpha-1-microglobulin, which belongs to the lipocalin superfamily, and bikunin. A1M is normally present as a free form and as a complex with IgA in the blood, spinal fluid, and urine. A1M inhibits neutrophil chemotaxis to endotoxin-activated serum. [OMIM: 176870] Abnormal plasma/serum levels can be seen in liver or kidney disorders, and also in clinical conditions such as HIV and mood disorders. Urinary A1M is used for the early detection and monitoring of kidney tubular disorders such as heavy metal intoxications, diabetic nephropathy, urinary outflow disorders or pyelonephritis). PMID: 15256311 Increased urinary excretion of α1-microglobulin in tubular proteinuria indicates reduced tubular reabsorption under normal glomerular filtration conditions. This form of proteinuria is typical for chronic interstitial nephropathy and for acute and chronic tubular damage caused by endogenous and exogenous tubular toxins. In renal failure, plasma levels of this microprotein increase from an early stage. The resultant protein hyperfiltration in the residual nephron causes increased renal excretion as re-absorption capacity is exceeded. α1-Microglobulin can be used as a marker to diagnose tubulo-interstitial nephropathy, for example, at an early stage, or rule it out with a high degree of certainty. Acute and chronic forms of tubular insufficiency (all forms of primary and secondary Fanconi syndrome), heavy metal intoxication, nephrotoxic side-effects of pharmaceuticals, and rejection reactions following kidney transplantation can also be excluded. Source: Regenstrief LOINC, PMID: 15256311

Fully-Specified Name

Component
Alpha-1-Microglobulin/Creatinine
Property
MRto
Time
Pt
System
Urine
Scale
Qn
Method

Additional Names

Short Name
A1 Microglob/Creat Ur
Display Name
Alpha-1-Microglobulin/Creatinine (U) [Mass ratio]
Consumer Name Alpha Get Info
Alpha-1-Microglobulin/Creatinine, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.21
Last Updated
Version 2.70
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG51319-8 Alpha-1-Microglobulin/Creatinine|MRto|Urine

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Alpha-1-Mikroglobulin/Kreatinin-Ratio /U
de-DE German (Germany) Alpha-1-Mikroglobulin/Creatinin:Massenverhältnis:Zeitpunkt:Urin:Quantitativ:
Synonyms: a1-Mikroglobulin
es-ES Spanish (Spain) Alfa 1-microglobulina/Creatinina:Relacion de Masa:Punto temporal:Orina:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Alfa-1-Microglobulina / Creatinina:Relación de masa:Punto temporal:Orina:Cuantitativo:
et-EE Estonian (Estonia) Alfa-1-mikroglobuliin/kreatiniin:MRto:Pt:U:Qn:
Synonyms: Juhuslik Kvantitatiivne Uriin
fr-CA French (Canada) Alpha-1-microglobuline/Créatinine:Ratio de masse:Temps ponctuel:Urine:Quantitatif:
fr-FR French (France) Alpha-1-microglobuline/créatinine:Masse ratio:Ponctuel:Urine:Numérique:
fr-BE French (Belgium) Alpha-1-microglobuline/Créatinine:Ratio de masse:Temps ponctuel:Urine:Quantitatif:
Synonyms: Rapport de masse
it-IT Italian (Italy) Alfa-1-Microglobulina/Creatinina:MRto:Pt:Urine:Qn:
Synonyms: Chimica Punto nel tempo (episodio) Rapporto di Massa
nl-NL Dutch (Netherlands) alfa-1-microglobuline/creatinine:massaverhouding:moment:urine:kwantitatief:
Synonyms: kreatinine
pt-BR Portuguese (Brazil) Alfa-1-Microglobulina/Creatinina:MCrto:Pt:Urina:Qn:
Synonyms: ; A1 Microglob; HC; Alpha-1-Microglycoprotein; Protein Human Complex; Creat; CR; mRto; Mass concentration ratio; Point in time; Random; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; Alfa; I; Chemistry; UCr
ru-RU Russian (Russian Federation) Альфа-1-Микроглобулин/Креатинин:МассОтн:ТчкВрм:Моча:Колич:
Synonyms: Количественный Масс отношение Точка во времени;Момент
tr-TR Turkish (Turkey) Alfa-1-Mikroglobulin/Kreatinin:KütlOr:Zmlı:İdrar:Kant:
zh-CN Chinese (China) Alpha-1-微球蛋白/肌酐:质量比率:时间点:尿液:定量型:
Synonyms: Ⅰ A1 型 A1MG;A-1-MG;A1-MG;Alpha-1-MG;Alpha-1-小球蛋白;Alpha1-小球蛋白;Alpha-1-微小球蛋白;Alpha1-微小球蛋白;Alpha-1-微小糖蛋白;Alpha1-微小糖蛋白;Alpha1-微球蛋白;HC;α1-MG;α1-小球蛋白;α1-微小球蛋白;α1-微小糖蛋白;α1-微球蛋白;人复合蛋白;人复合蛋白（Protein Human Complex，human complexforming protein，HC） CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 I UCr α α1 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉 尿液肌酐 尿液肌酸酐 尿肌酸酐 时刻;随机;随意;瞬间 来自于同一体系的两种分析物的质量之比;质量比 肌酸内酰胺 阿尔法

Example Units

Unit Source
mg/g{creat} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=48415-4