Version 2.79

Part Descriptions

LP150045-5   Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

LP16682-4   Coxiella burnetii
Coxiella burnetii is an obligate intracellular, pleomorphic bacillus and is the bacterium that causes Q fever. Its only known targets are monocytes and macrophages. C burnetii infection in humans is typically asymptomatic, but in acute disease can exhibit symptoms of a self-limited flu-like illness, pneumonia or hepatitis. Symptoms of chronic C burnetii infection include primarily endocarditis, but also hepatitis and chronic fatigue syndrome. Pregnant women infected with C burnetii may experience abortions, premature deliveries, and stillbirth. Ticks are the reservoir and vector for C burnetii, and cattle, sheep, and goats are the primary sources of infection in humans. C burnetii is transmitted in infected secretions, and people with predisposing factors such as underlying disease and compromised cell-mediated immunity are at a greater risk of symptomatic infection. PMID: 16481501 The shikimate dehydrogenase gene (aroE) is a housekeeping gene of C burnetti that is targeted in nucleic acid amplification assays to aid in the diagnose C burnetii infection. PMID: 23077126 Source: Regenstrief LOINC

Fully-Specified Name

Component
Coxiella burnetii
Property
Prid
Time
Pt
System
XXX
Scale
Nom
Method
Sequencing

Additional Names

Long Common Name
Coxiella burnetii identified in Specimen by Sequencing
Short Name
C burnet Spec Seq
Display Name
C. burnetii identified Sequencing Nom (Specimen)
Consumer Name Alpha Get Info
Coxiella burnetii test, Specimen

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.21
Last Updated
Version 2.78 (NAM)
Change Reason
Release 2.78: COMPONENT: Removed "Identified" from the component because it is implied by the Property "Prid"; Previous Releases: Changed method from Amplification/Sequencing because Amplification always occurs before sequencing
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Coxiella burnetii:Nachweis oder Identität:Zeitpunkt:XXX:Nominal:Sequenzierung
el-GR Greek (Greece) Βακτήριο Coxiella burnetii:Prid:Pt:XXX:Nom:Αλληλούχιση
Synonyms: Prid Βακτήριο Coxiella burnetii
es-ES Spanish (Spain) Coxiella burnetti:Presencia o identidad:Punto temporal:XXX:Nom:Secuenciación
es-MX Spanish (Mexico) Coxiella burnetii identificada:Presencia o identidad:Punto temporal:XXX:Nominal:Secuenciación
fr-CA French (Canada) Coxiella burnetii:Présence ou identité:Temps ponctuel:XXX:Nominal:Séquençage
fr-FR French (France) Coxiella burnetii:Identification:Ponctuel:Milieux divers:Résultat nominal:Séquençage
fr-BE French (Belgium) Coxiella burnetii:Présence ou identité:Temps ponctuel:XXX:Nominal:Séquençage
it-IT Italian (Italy) Coxiella burnetii:Prid:Pt:XXX:Nom:Sequenziamento
Synonyms: Microbiologia Presenza o Identità Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) Coxiella burnetii:identificator:moment:XXX:nominaal:sequencing
pt-BR Portuguese (Brazil) Identificação de Coxiella burnetii:Ident:Pt:XXX:Nom:Amplificação/sequenciamento
Synonyms: ; C burnet; Q fev; C burnetii; Qfever; Coxiella burnettii; Q fever; Identity or presence; Point in time; Random; Misc; Miscellaneous; Unspecified; Other; Nominal; Amp/Seq; Amp/Seq; Isolated; Microbiology
tr-TR Turkish (Turkey) Coxiella burnetii:MevcKimlik:Zmlı:XXX:Snf:Sekanslama
Synonyms: Dizi tayini
zh-CN Chinese (China) 贝氏柯克斯体:存在与否或特征标识:时间点:XXX:名义型:序列测定
Synonyms: 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 伯内特科克斯立克次体;Q 热 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 存在;存在与否;特征标识;身份;身份标识 序列分析;测序 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=49124-1