Version 2.76

Part Description

LP30845-9   Bile acid pattern
Bile acids (BAs) play a primary role in digesting dietary fats. Primary BAs are produced in the liver by either the classic or alternative pathway. CYP7A1 controls the production of primary BAs in the liver. The primary BAs (chenodeoxycholic acid and cholic acid) are conjugated to either glycine or taurine to create conjugated primary BAs, which are stored in the gallbladder. Once released into the intestinal circulation, primary BAs are modified by gut bacteria (e.g., deconjugated) to form secondary BAs. Secondary BAs are actively reabsorbed in the terminal ileum, and travel back to the liver through the portal circulation. PMID: 28249284

Different disorders are associated with various patterns of primary and secondary BA levels. Examples of disorders and their associated BA patterns include:
Disorders of BA synthesis (information from PMID: 18577977):
1) Inborn errors of bile acid synthesis including cerebrotendinous xanthomatosis, Zellweger syndrome, and a variety of other enzyme deficiencies - low or absent BAs
2) Bile acid conjugation defects - increased levels of unconjugated cholic and deoxycholic acid, lack of chenodeoxycholic acid

Disorders of BA metabolism (information from PMID: 28249284):
1) Inflammatory bowel disease - reduced deconjugation by gut bacteria, lower levels of secondary BAs
2) Irritable bowel syndrome - reduced deconjugation, increased levels of primary conjugated BAs, lower levels of secondary BAs
3) Short bowel syndrome - reduced levels of secondary and tertiary BAs
4) Obesity - lower levels of both primary BAs Source: Regenstrief LOINC

Fully-Specified Name

Component
Bile acid pattern
Property
Imp
Time
Pt
System
Urine
Scale
Nar
Method

Additional Names

Short Name
Bile Ac Pattern Ur-Imp
Display Name
Bile acid pattern Nar (U) [Interp]
Consumer Name Alpha Get Info
Interpretation of Bile acid pattern test result, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.21
Last Updated
Version 2.73
Order vs. Observation
Observation
Common Test Rank Get Info
9648

Member of these Groups Get Info

LOINC Group Group Name
LG13375-7 Bile acid pattern|Imp|Pt|ANYUrine
LG35989-9 Bile acid pattern|Imp|Urine

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Gallensäuremuster:Interpretation:Zeitpunkt:Urin:Freitext:
es-ES Spanish (Spain) Patrón de ácidos biliares:Impresión/interpretación del estudio:Punto temporal:Orina:Narrativo:
es-MX Spanish (Mexico) Patrón de ácidos biliares:Impresión / interpretación del estudio:Punto temporal:Orina:Narrativo:
fr-CA French (Canada) Profil acide biliaire:Impression/interprétation d'étude:Temps ponctuel:Urine:Narratif:
fr-FR French (France) Acides biliaires Profil:Interprétation:Ponctuel:Urine:Résultat textuel:
fr-BE French (Belgium) Profil acide biliaire:Impression/interprétation d'étude:Temps ponctuel:Urine:Narratif:
it-IT Italian (Italy) Acido biliare, profilo:Imp:Pt:Urine:Nar:
Synonyms: Acidi biliari Chimica Impressione/interpretazione di studio Profilo acidi biliari Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) galzurenprofiel:interpretatie:moment:urine:tekstueel:
pt-BR Portuguese (Brazil) Ácido biliar padrão:Imp:Pt:Urina:Nar:
Synonyms: ; Bile Ac Pattern; Bile salt; Bile acid.total; Interpretation; Interp; Impression; Impressions; Point in time; Random; Ur; UR; Urn; UA; Narrative; Report; Acd; Acids; Chemistry
ru-RU Russian (Russian Federation) Желчная кислота паттерн:Впчт:ТчкВрм:Моча:Опис:
Synonyms: Впечатление/интерпретация исследования Желчные кислоты Желчные кислоты профиль Описательный Точка во времени;Момент
tr-TR Turkish (Turkey) Safra asidi patterni:İzlnm:Zmlı:İdrar:Öykü:
zh-CN Chinese (China) 胆汁酸模式:印象:时间点:尿液:叙述型:
Synonyms: BA;TBA;总胆汁酸;胆汁酸.总计;胆汁酸盐;胆盐 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 印象是一种诊断陈述,始终是对其他某种观察指标的解释或抽象(一系列检验项目结果、一幅图像或者整个某位病人),而且几乎总是由某位专业人员产生。;检查印象;检查印象/解释;检查的印象/解释;检查解释;解释;阐释 叙述;叙述性文字;报告;报告型;文字叙述;文本叙述型;文本描述;文本描述型 尿;小便;下泉 时刻;随机;随意;瞬间 精汁;胆;胆液 胆汁酸模式(模式特征、特征模式、图谱、式样、组份、组分、成员) 酸

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=49254-6