49310-6
Nuclear Ab pattern [Interpretation] in Serum Narrative
Active
Part Descriptions
LP16670-9 Nuclear
The nucleus of a cell contains the body's genetic material. It is the site of transcriptional regulation, RNA processing and DNA synthesis and transcription.
PMID: 24563360
Source: Regenstrief LOINC
LP29188-7 Nuclear Ab pattern
Nuclear antibody patterns are distinguishable fluorescent designs that occur when autoantibodies in patient serum bind with mammalian cells that have been fixed to a glass slide. The bound autoantibodies are then coated with anti-human IgG antibodies that are tagged with a fluorochrome stain. The slide is then viewed under a fluorescent microscope where the various patterns of fluorescence can be seen depending upon what autoantibodies are present. The fluorescent patterns typically reported include nuclear, centromere, or nucleolar. The nuclear pattern is more specifically described as speckled, homogenous, or peripheral. The patterns seen are associated with the autoantibodies that are produced in certain systemic autoimmune diseases including systemic lupus erythematosus (SLE), scleroderma (SSc), polymyositis/dermatomyositis (PM/DM), and rheumatoid arthritis (RA). The autoantibodies associated with these autoimmune diseases bind with antigens that are present in all cells of the body and destroy tissue in various organs. Many of the antibodies are present in more than one disorder and in differing titers. PMID: 19277826
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Nuclear Ab pattern
- Property
- Imp
- Time
- Pt
- System
- Ser
- Scale
- Nar
- Method
Additional Names
- Short Name
- ANA Pat Ser-Imp
- Display Name
- Nuclear Ab pattern Nar (S) [Interp]
- Consumer Name Alpha Get Info
- Interpretation of Nuclear Ab pattern test result, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.21
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 6222
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG1864-0 | Nuclear Ab pattern| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: ANA IF Interpret. |
| de-DE | German (Germany) | Nukleärer Ak-Muster: |
| es-ES | Spanish (Spain) | Nuclear Patrón de anticuerpos: |
| es-MX | Spanish (Mexico) | Patrón de Ab nuclear: |
| fr-CA | French (Canada) | Nucléaire, Patron des Ac: |
| fr-FR | French (France) | Noyau anticorps aspect: |
| fr-BE | French (Belgium) | Nucléaire Anticorps.Profil des Ac: Synonyms: Anticorps |
| it-IT | Italian (Italy) | Nucleare profilo Ab: Synonyms: anticorpo Impressione/interpretazione di studio profilo anticorpo Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | nucleaire As-patroon: Synonyms: antistof; |
| pt-BR | Portuguese (Brazil) | Nuclear Ac padrão: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Ядерный Ат паттерн: Synonyms: Антитело Впечатление/интерпретация исследования Описательный Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | Nükleer Ab yapısı: Synonyms: Ak Ak yapısı Çekirdek |
| zh-CN | Chinese (China) | 细胞核 抗体模式: Synonyms: Ab; |
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