49467-4

CD22 Ag [Presence] in Tissue by Immune stain

Active

Part Descriptions

LP68372-9 CD22
CD22 or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. Generally speaking, CD22 is a regulatory molecule that prevents the overactivation of the immune system and the development of autoimmune diseases.

CD22 is a sugar binding transmembrane protein, which specifically binds sialic acid with an immunoglobulin (Ig) domain located at its N-terminus. The presence of Ig domains makes CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signalling.

EBV (Epstein-Barr virus) is known to bind to the B lymphocyte via the CD22 receptor. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, CD22

LP20041-7 CD22
Found on mature B-cells.
Associated with some B-cell ALL and most mature B-cell neoplasms Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: CD22 Ag:PrThr:Pt:Tiss:Ord:Immune stain
Long Common Name: CD22 Ag [Presence] in Tissue by Immune stain
Short Name: CD22 Ag Tiss Ql ImStn
Display Name: CD22 Ag Immune stain Ql (Tiss)
Consumer Name Alpha Get Info: CD22 antigen, Tissue

Part Model Get Info

Component
CD22 Ag
LP64428-3
- Analyte
  CD22 Ag
  LP64428-3
  - Component Numerator
    CD22 Ag
    LP64428-3
    - Component Numerator Core
      CD22
      LP68372-9
    - Component Numerator Core Suffix
      Ag
      LP20666-1
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Tiss
LP7641-6
- System Core
  Tiss
  LP7641-6
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Immune stain
LP6333-1

Basic Attributes

Class: PATH
Type: Laboratory
First Released: Version 2.22
Last Updated: Version 2.56 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	CD22 Ag:Přítomnost nebo práh:Časový bod:Tkáně a stěry:Ordinální:Imunobarvení
el-GR	Greek (Greece)	CD22 Αντιγόνο:PrThr:Pt:Ιστός:Ord:Ανοσολογική χρώση Synonyms: CD22 Ord PATH PrThr Pt Ανοσολογική χρώση Αντιγόνο Ιστός
es-ES	Spanish (Spain)	CD22 Antígeno:PrThr:Punto temporal:Tejido:Ord:Tinción de inmunohistoquímica
es-MX	Spanish (Mexico)	CD22 Ag:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Mancha inmune
et-EE	Estonian (Estonia)	CD22 antigeen:PrThr:Pt:Tis:Ord:Immuunvärv Synonyms: Järgarvuline Juhuslik Kude
fr-CA	French (Canada)	CD22, Ag:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
fr-FR	French (France)	CD22 Ag:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Coloration immune
fr-BE	French (Belgium)	CD22 Ag:PrThr:Temps ponctuel:Tissu:Ordinal:Coloration immunologique Synonyms: Antigène Coloration. Méthode mmunologique
it-IT	Italian (Italy)	CD22, Ag:PrThr:Pt:Tessuto:Ord:Colorazione immunologica Synonyms: Patologia Presenza o Soglia Punto nel tempo (episodio) Tessuto & Strisci
nl-NL	Dutch (Netherlands)	CD22 Ag:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunokleuring Synonyms: antigeen
pl-PL	Polish (Poland)	CD22 Ag:granica wykrywalności:punkt w czasie:tkanka i rozmazy:uporządkowany:barwienie immunohistochemiczne Synonyms: CD22
pt-BR	Portuguese (Brazil)	CD22 Ag:ACnc:Pt:Tecido:Ord:Imunocoloração Synonyms: Arbitrary concentration; Point in time; Random; Tissue; Ql; Ordinal; QL; Qualitative; Qual; Screen; ImStn; Immunostain; Immunohistochemical stain; IHC; Antigen; Antigens; Imun; Imune; Imm; Leu-14; B-3; To-15; B3; Leu14; BL-CAM; Lyb8; PATHOLOGY
ru-RU	Russian (Russian Federation)	CD22 Аг:PrThr:ТчкВрм:Тк:Пор:Иммуногистохимическая окраска Synonyms: Порядковый Ткань и мазки Точка во времени;Момент
tr-TR	Turkish (Turkey)	CD22 Ag:MevcEşik:Zmlı:Doku:Srl:İmmün boyama Synonyms: Antijen Mevcut
zh-CN	Chinese (China)	CD22 抗原:存在情况或阈值:时间点:组织与涂片:序数型:免疫染色法 Synonyms: Ag B3 B-3 BL-CAM B-淋巴细胞粘附分子 B-淋巴细胞粘附分子（B lymphocyte cell adhesion molecule，BL-CAM） CD22 Ag Leu14 Leu-14 Lyb8 To-15 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法发现于成熟 B-细胞之上。与某些 B-细胞急性淋巴细胞白血病以及大多数成熟 B-细胞肿瘤相关。存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间未作说明的组织;组织;组织 & 涂片染法染色方法染色法着色着色方法着色法

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.