49617-4

Carbapenem resistance blaKPC gene [Presence] by Molecular method

Active

Part Description

LP64707-0 Bacterial carbapenem resistance blaKPC gene
Non-susceptibility to carbapenems in gram-negative bacilli by means of the enzyme KPC (Klebsiella pneumoniae carbapenemase) is becoming more common. The gene beta-lactamase KPC (bla(KPC)) encodes KPC enzyme production, which in turn hydrolyzes and inactivates carbapenem antibiotics. KPC enzymes are a class A beta lactamases with several variants (KPC-2, KPC-3, etc) known. Various methods are used to detect specific portions of genes encoding KPC production. Carbapenemases can also be detected by other methods, including the modified Hodge test to detect carbapenemase production in isolates and minimum inhibitory concentration (MIC) to determine level of resistance. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Bacterial carbapenem resistance blaKPC gene:PrThr:Pt:Isolate/Specimen:Ord:Molgen
Long Common Name: Carbapenem resistance blaKPC gene [Presence] by Molecular method
Short Name: blaKPC Islt/Spm Ql
Display Name: Carbapenem resistance blaKPC gene Molgen Ql (Islt/Spec)
Consumer Name Alpha Get Info: Carbapenem resistance blaKPC gene

Part Model Get Info

Component
Bacterial carbapenem resistance blaKPC gene
LP64707-0
- Analyte
  Bacterial carbapenem resistance blaKPC gene
  LP64707-0
  - Component Numerator
    Bacterial carbapenem resistance blaKPC gene
    LP64707-0
    - Component Numerator Core
      Bacterial carbapenem resistance blaKPC gene
      LP64707-0
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Isolate/Specimen
LP266970-5
- System Core
  Isolate/Specimen
  LP266970-5
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Molgen
LP6404-0

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: ABXBACT
Type: Laboratory
First Released: Version 2.22
Last Updated: Version 2.73 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Corrected Component from "Bacterial carbapenemase resistance" to "Bacterial carbapenem resistance" (because the bacteria are resistant to carbapenem antibiotics by virtue of producing carbapenemase) and removed parentheses around and within the gene name according to recommended nomenclature [PMID: 25249841]; Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
Order vs. Observation: Both
Common Test Rank Get Info: 1861

Member of these Panels

LOINC	Long Common Name
104991-5	Bacterial resistance panel
85762-3	Blood pathogens panel by NAA with non-probe detection in Positive blood culture
97324-8	Carbapenem resistant bacteria identification and resistance panel by Molecular genetics method
85502-3	Carbapenemase resistance genes panel by Molecular genetics method
93698-9	Gram negative bacterial resistance panel by Molecular genetics method
93407-5	Gram negative blood culture panel by NAA with probe detection in Positive blood culture
97608-4	Joint pathogens panel - Synovial fluid by NAA with non-probe detection
114487-2	Respiratory pathogens 33-plexA DNA and RNA panel - Lower respiratory specimen
114484-9	Respiratory pathogens 34-plexA DNA and RNA panel - Lower respiratory specimen
92958-8	Respiratory pathogens DNA and RNA panel - Lower respiratory specimen by NAA with non-probe detection

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Gen blaKPC bakteriální rezistence na karbapenemy:Přítomnost nebo práh:Časový bod:Izolát/vzorek:Ordinální:Molekulární genetika
de-AT	German (Austria)	Synonyms: Carbapenem Resistenz Gen (blaKPC) ql.
de-DE	German (Germany)	Bakterielle Carbapenem-Resistenz blaKPC-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Isolat oder Probenmaterial:Ordinal:Molekulargenetisch
el-GR	Greek (Greece)	Γονίδιο blaKPC βακτηριακής ανθεκτικότητας στις καρβαπενέμες:PrThr:Pt:Απομονωθέν στέλεχος/Δείγμα:Ord:Μοριακή γενετική Synonyms: ABXBACT Ord PrThr Pt Απομονωθέν στέλεχος/Δείγμα Απομονωμένο στέλεχος Γονίδιο Γονίδιο blaKPC βακτηριακής ανθεκτικότητας στις καρβαπενέμες Δείγμα Καρβαπενέμη Μοριακή γενετική
es-ES	Spanish (Spain)	Gen bla(KPC):PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular
es-MX	Spanish (Mexico)	Gen blaKPC de resistencia a carbapenémicos bacterianos:Presencia o umbral:Punto temporal:Aislado o espécimen:Ordinal:Genética molecular
fr-CA	French (Canada)	Gène bactérien de résistance à la carbapéném blaKPC:Présence-Seuil:Temps ponctuel:Isolat/Échantillon:Ordinal:Molgen
fr-FR	French (France)	Résistance bactérienne aux carbapénèmases gène blaKPC:Présence/Seuil:Ponctuel:Isolat/échantillon:Qualitatif:Biologie moléculaire
it-IT	Italian (Italy)	Resistenza batterica ai carbapenemici, gene blaKPC:PrThr:Pt:Isolato/Campione:Ord:Molgen Synonyms: Gene blaKPC di resistenza batterica ai carbapenemici Genetica molecolare Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici
nl-NL	Dutch (Netherlands)	bacteriële carbapenemresistentie blaKPC-gen:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek Synonyms: isolaat/specimen molgen
pl-PL	Polish (Poland)	Oporność bakterii na karbapenemy blaKPC gen:granica wykrywalności:punkt w czasie:szczep/izolat lub próbka:uporządkowany:genetyka molekularna Synonyms: Antybiotyk karbapenemowy diagnostyka molekularna Gen blaKPC oporności bakterii na karbapenemy;Gen blaKPC warunkujący oporność bakterii na karbapenemy
pt-BR	Portuguese (Brazil)	bla(KPC) gene:ACnc:Pt:Isolado:Ord:Sonda com limite de detecção da amplificação de alvo Synonyms: Arbitrary concentration; Point in time; Random; Islt; Isol; Ql; Ordinal; QL; Qualitative; Qual; Screen; PCR; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; ANTIBIOTIC SUSCEPTIBILITIES
zh-CN	Chinese (China)	细菌碳青霉烯类耐药 blaKPC 基因:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法 Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应分离株/标本（样本、样品、试样）分离物;分离菌;分离菌株;隔离种群受检物存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）抗力抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类抗耐性抵抗力抵抗性时刻;随机;随意;瞬间样品样本电阻碳青霉烯类;碳青霉烯类抗生素细菌性细菌的细菌碳青霉烯类（碳青霉烯类抗生素、碳青霉烯）耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型） blaKPC 基因;细菌碳青霉烯酶（碳青黴烯酶、碳青霉烯水解酶）耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型）blaKPC 基因耐性试样遗传基因;遗传因子;吉恩;生物基因阻力

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.