49714-9
Interleukin 8 [Mass/volume] in Body fluid
Active
Part Descriptions
LP30829-3 Interleukin 8
Interleukin-8 (IL-8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 protein is encoded by the IL8 gene.
Interleukin-8 is often associated with inflammation. As an example, it has been cited as a proinflammatory mediator in gingivitis and psoriasis. The fact that Interleukin-8 secretion is increased by oxidant stress and conversely, Interleukin-8, by causing recruitment of inflammatory cells induces a further increase in oxidant stress mediators, makes it a key parameter in localized inflammation.
If a pregnant mother has high levels of interleukin-8, there is an increased risk of schizophrenia in her offspring. High levels of Interleukin 8 have been shown to reduce the likelihood of positive responses to antipsychotic medication in schizophrenia.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Wikipedia
LP30829-3 Interleukin 8
The Interleukins belong to the family termed cytokines. They are peptides used by immune and inflammatory cells to communicate and control cell operations. The cytokines have some similar actions to the Growth Factors but Growth Factors regulate proliferation of non-immune cells. Interleukin 8 is a 6,000 - 8000 molecular weight glycoprotein produced primarily by macrophages and monocytes. Its primary target cells are neutrophils. Interleukin 8 is a chemotactic agent for monocytes and neutrophils. Interleukin 8 causes oxygen radical and enzyme release by neutrophils and mobilizes products into circulation. Interleukin 8 is stimulated by Interleukin 1 and Tumor Necrosis Factor.
Source: Inter Science Institute, Inter Science Institute
LP7238-1 Body fld
The LOINC "Body fld" System represents body fluids other than serum, plasma, blood, urine, and cerebrospinal fluid. When a LOINC term with the System "Body fld" is used, the specific specimen source or body fluid type should be reported elsewhere with the result. Where more specific terms for pleural, peritoneal, synovial fluid, etc. exist, we encourage you to use the more specific terms. In contrast to "Body fld", the System "Asp" in LOINC represents the fluid withdrawn during an aspiration procedure from an abnormal collection of fluid, such as from an abscess or cyst. "Asp" is used for abnormal fluid collections that are aspirated, while "Body fld" is used for named body fluids, such as synovial fluid or peritoneal fluid, that are not inherently pathologic.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Interleukin 8
- Property
- MCnc
- Time
- Pt
- System
- Body fld
- Scale
- Qn
- Method
Additional Names
- Short Name
- Il8 Fld-mCnc
- Display Name
- Interleukin 8 (Body fld) [Mass/Vol]
- Consumer Name Alpha Get Info
- Interleukin 8, Body fluid
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.22
- Last Updated
- Version 2.34
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Interleukin-8: |
es-ES | Spanish (Spain) | Interleucina 8: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Interleucina 8: |
et-EE | Estonian (Estonia) | Interleukiin 8: Synonyms: Juhuslik Kehavedelik Kvantitatiivne |
fr-CA | French (Canada) | Interleukine 8: |
fr-FR | French (France) | Interleukine-8: |
fr-BE | French (Belgium) | Interleukine 8: Synonyms: IL 8 |
it-IT | Italian (Italy) | Interleuchina 8: Synonyms: Chimica Concentrazione di Massa Liquido corporeo Punto nel tempo (episodio) |
nl-NL | Dutch (Netherlands) | interleukine 8: |
pt-BR | Portuguese (Brazil) | Interleucina 8: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Интерлейкин 8: Synonyms: Количественный Массовая концентрация Тела жидкость Точка во времени; |
tr-TR | Turkish (Turkey) | İnterlökin 8: |
zh-CN | Chinese (China) | 白细胞介素 8: Synonyms: IL Il8; |
Example Units
Unit | Source |
---|---|
pg/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=49714-9
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright