LOINC
Version 2.72

49732-1Interleukin 6 [Mass/volume] in Body fluidActive

Part Descriptions

LP16474-6   Interleukin 6
Interleukin-6 (IL-6) is a protein that in humans is encoded by the IL6 gene.

IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. In terms of host response to a foreign pathogen, IL-6 has been shown, in mice, to be required for resistance against the bacterium, Streptococcus pneumoniae. IL-6 is also a "myokine," a cytokine produced from muscle, and is elevated in response to muscle contraction. It is significantly elevated with exercise, and precedes the appearance of other cytokines in the circulation. During exercise, it is thought to act in a hormone-like manner to mobilize extracellular substrates and/or augment substrate delivery. Additionally, osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine. IL-6's role as an anti-inflammatory cytokine is mediated through its inhibitory effects on TNF-alpha and IL-1, and activation of IL-1ra and IL-10. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP16474-6   Interleukin 6
The Interleukins belong to the family termed cytokines. They are peptides used by immune and inflammatory cells to communicate and control cell operations. The cytokines have some similar actions to the Growth Factors but Growth Factors regulate proliferation of non-immune cells. Interleukin 6 is a 25,000 molecular weight glycoprotein produced primarily in macrophages, T cells, fibroblasts and endothelial cells. Its primary target cells are T and B cells and neutrophils. Its main actions are involvement in terminal differentiation of B cells to antibody secreting plasma cells, activation of T cells and stimulation of hepatocyte production of acute phase proteins. Interleukin stimulates Prolactin, Growth Hormone, Luteinizing Hormone, Follicle Stimulating Hormone and ACTH. Release is stimulated by Interleukin 1a and b, Vasoactive Intestinal Polypeptide, and Prostaglandin E2. Release is not affected by aspirin or indomethacin. Levels are elevated in multiple myeloma, rheumatoid arthritis, systemic lupus erythematosus, meningococcus meningitis and infectious peritonitis. Source: Inter Science Institute, Inter Science Institute

LP7238-1   Body fld
The LOINC "Body fld" System represents body fluids other than serum, plasma, blood, urine, and cerebrospinal fluid. When a LOINC term with the System "Body fld" is used, the specific specimen source or body fluid type should be reported elsewhere with the result. Where more specific terms for pleural, peritoneal, synovial fluid, etc. exist, we encourage you to use the more specific terms. In contrast to "Body fld", the System "Asp" in LOINC represents the fluid withdrawn during an aspiration procedure from an abnormal collection of fluid, such as from an abscess or cyst. "Asp" is used for abnormal fluid collections that are aspirated, while "Body fld" is used for named body fluids, such as synovial fluid or peritoneal fluid, that are not inherently pathologic. Source: Regenstrief LOINC

Fully-Specified Name

Component
Interleukin 6
Property
MCnc
Time
Pt
System
Body fld
Scale
Qn
Method

Additional Names

Short Name
Il6 Fld-mCnc
Display Name
Interleukin 6 (Body fld) [Mass/Vol]
Consumer Name Alpha
Interleukin 6, Body fluid

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.22
Last Updated
Version 2.34
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (China)
白细胞介素 6:质量浓度:时间点:体液:定量型:
nl-NLDutch (Netherlands)
interleukine 6:massa/volume:moment:lichaamsvocht:kwantitatief:
et-EEEstonian (Estonia)
Interleukiin 6:MCnc:Pt:Fx:Qn:
fr-BEFrench (Belgium)
Interleukine 6:Concentration de masse:Temps ponctuel:Liquide biologique:Quantitatif:
fr-CAFrench (Canada)
Interleukine 6:Concentration de masse:Temps ponctuel:Liquide biologique:Quantitatif:
fr-FRFrench (France)
Interleukine-6:Masse/Volume:Ponctuel:Liquide biologique:Numérique:
de-DEGerman (Germany)
Interleukin-6:Massenkonzentration:Zeitpunkt:Körperflüssigkeit:Quantitativ:
it-ITItalian (Italy)
Interleuchina 6:MCnc:Pt:Liquido corporeo:Qn:
pt-BRPortuguese (Brazil)
Interleucina 6:MCnc:Pt:LiqOrg:Qn:
ru-RURussian (Russian Federation)
Интерлейкин 6:МассКонц:ТчкВрм:Тело ждк:Колич:
es-MXSpanish (Mexico)
Interleucina 6:Concentración de masa:Punto temporal:Fluído corporal:Cuantitativo:
es-ESSpanish (Spain)
Interleukina 6:Concentración de masa:Punto temporal:Fluido corporal:Qn:
tr-TRTurkish (Turkey)
İnterlökin 6:KütlKons:Zmlı:Vücut sv:Kant:

Example Units

Unit Source
pg/mL Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=49732-1