49816-2

2-Oxo,3-Methylvalerate/Creatinine [Molar ratio] in 24 hour Urine

Active

Part Descriptions

LP18407-4 2-Oxo,3-Methylvalerate
3-Methyl-2-oxovaleric acid is a metabolite of isoleucine in man, animals and bacteria. It is the alpha-keto acid analogue of isoleucine. 3-Methyl-2-oxovaleric acid is produced from isoleucine by cytosolic branched chain aminotransferase 1 (EC:2.6.1.42), whereupon it is further degraded by branched chain keto acid dehydrogenase E1 to 2-Methyl-1-hydroxybutyl-ThPP. It is used as a clinical marker for maple syrup urine disease (MSUD). MSUD is caused by a deficiency of the branched-chain -keto acid dehydrogenase compex resulting in an accumulation of branched-chain amino acids and the corresponding -keto-and -hydroxy acids in blood, urine and cerebrospinal fluid causing neurological damage and mental retardation. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, 2-Oxo,3-Methylvalerate

LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

LOINC Names Get Info

Fully-Specified Name: 2-Oxo,3-Methylvalerate/Creatinine:SRto:24H:Urine:Qn:
Long Common Name: 2-Oxo,3-Methylvalerate/Creatinine [Molar ratio] in 24 hour Urine
Short Name: 2Oxo3Me-valerate/Creat 24h Ur-sRto
Display Name: 2-Oxo,3-Methylvalerate/Creatinine (24H U) [Molar ratio]
Consumer Name Alpha Get Info: 2-Oxo,3-Methylvalerate/Creatinine, Urine

Part Model Get Info

Component
2-Oxo,3-Methylvalerate/Creatinine
LP284718-6
- Analyte
  2-Oxo,3-Methylvalerate/Creatinine
  LP284718-6
  - Component Numerator
    2-Oxo,3-Methylvalerate
    LP18407-4
    - Component Numerator Core
      2-Oxo,3-Methylvalerate
      LP18407-4
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Creatinine
    LP32035-5
    - Component Denominator Core
      Creatinine
      LP32035-5
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
SRto
LP6868-6
Time
24H
LP6924-7
- Time Core
  24H
  LP6924-7
- Time Modifier
  NULL
System
Urine
LP7681-2
- System Core
  Urine
  LP7681-2
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.22
Last Updated: Version 2.42 (MIN)
Order vs. Observation: Observation

Member of these Groups Get Info

LOINC Group	Group Name
LG35393-4	2-Oxo,3-Methylvalerate/Creatinine\|SRto\|Urine

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	2-oxo-3-methylvalerát/kreatinin:Látkový poměr:24 hodin:Moč:Kvantitativní:
el-GR	Greek (Greece)	3-μεθυλο-2-οξο-βαλερικό οξύ/Κρεατινίνη:SRto:24H:Ούρα:Qn: Synonyms: 24H 3-μεθυλο-2-οξο-βαλερικό οξύ CHEM Qn SRto Κρεατινίνη Ούρα
es-ES	Spanish (Spain)	2-Oxo,3-Metilvalerato/Creatinina:Relacion de Sustancia:24 horas:Orina:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	2-oxo, 3-metilvalerato / creatinina:Proporción de sustancia:24H:Orina:Cuantitativo:
fr-CA	French (Canada)	2-oxo,3-méthylvalérate/Créatinine:Ratio de substance:24 h:Urine:Quantitatif:
fr-FR	French (France)	2-oxo-3-méthylvalérate/créatinine:Moles ratio:24H:Urine:Numérique:
fr-BE	French (Belgium)	2-oxo,3-méthylvalérate/Créatinine:Ratio de substance:24 h:Urine:Quantitatif:
it-IT	Italian (Italy)	2-Osso,3-Metilvalerato/Creatinina:Srto:24h:Urine:Qn: Synonyms: 24 Ore Chimica Rapporto di sostanza
nl-NL	Dutch (Netherlands)	2-oxo,3-methylvaleraat/creatinine:molaire verhouding:24 uur:urine:kwantitatief: Synonyms: 24U kreatinine
pl-PL	Polish (Poland)	2-Okso-3-metylwalerian/kreatynina:współczynnik molowy:24h:mocz:ilościowy: Synonyms: 24 godziny
pt-BR	Portuguese (Brazil)	2-Oxo,3-Metilvalerato/Creatinina:SCrto:24H:Urina:Qn: Synonyms: ; 2Oxo3Me-valerate; 2-keto-3-methylvaleric acid; 2-keto-3-methylvalerate; 2-oxo,3-methylvaleric acid; Creat; CR; 2Oxo3Me-valerate; sRto; Substance concentration ratio; 1 day; 24 hours; 24HR; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; III; II; Chemistry; UCr
ru-RU	Russian (Russian Federation)	2-Оксо,3-Метилвалерат/Креатинин:МольОтн:24 часа:Моча:Колич: Synonyms: Количественный Мольная доля;Молярная доля;Отношение концентраций
tr-TR	Turkish (Turkey)	2-Okzo,3-Metilvalerat/Kreatinin:SOrn:24Sa:İdrar:Kant: Synonyms: SubsOranı
zh-CN	Chinese (China)	2-氧代,3-甲基戊酸/肌酐:物质的量比率:24小时:尿液:定量型: Synonyms: 1天;1日;24.0小时;一天;一日;二十四个小时;二十四小时 2Oxo3Me-戊酸;2-酮-3-甲基戊酸;2-酮基-3-甲基戊酸 Ⅱ Ⅲ CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 II III UCr 三化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类叁可用数量表示的;定量性;数值型;数量型;连续数值型标尺尿;小便;下泉尿液肌酐尿液肌酸酐尿肌酸酐物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值肌酸内酰胺

Example Units

Unit	Source
mmol/mol{creat}	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=49816-2

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.