49846-9

Hepatitis C virus core Ag [Presence] in Blood or Marrow from Donor

Active

Part Descriptions

LP200104-0 Hepatitis C virus core Ag
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

LP200105-7 Hepatitis C virus core
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

LOINC Names Get Info

Fully-Specified Name: Hepatitis C virus core Ag:PrThr:Pt:Bld/Bone mar^Donor:Ord:
Long Common Name: Hepatitis C virus core Ag [Presence] in Blood or Marrow from Donor
Short Name: HCV core Ag Bld/Mar Donr Ql
Display Name: HCV core Ag Ql (Bld/BM donor)
Consumer Name Alpha Get Info: Hepatitis C virus (HCV) Core antigen, Donor Blood Or Bone marrow

Part Model Get Info

Component
Hepatitis C virus core Ag
LP200104-0
- Analyte
  Hepatitis C virus core Ag
  LP200104-0
  - Component Numerator
    Hepatitis C virus core Ag
    LP200104-0
    - Component Numerator Core
      Hepatitis C virus core
      LP200105-7
    - Component Numerator Core Suffix
      Ag
      LP20666-1
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld/Bone mar^Donor
LP281786-6
- System Core
  Bld/Bone mar
  LP7060-9
- Super System
  Donor
  LP7742-2
Scale
Ord
LP7751-3
Method
NULL

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.22
Last Updated: Version 2.73 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Virus hepatitidy C core Ag:Přítomnost nebo práh:Časový bod:Krev/kostní dřeň^Dárce:Ordinální:
de-DE	German (Germany)	Hepatitis-C-Virus Core Ag:Nachweis oder Schwellenwert:Zeitpunkt:Blut oder Knochenmark^Donor:Ordinal:
el-GR	Greek (Greece)	Πυρήνας ιού ηπατίτιδας C Αντιγόνο:PrThr:Pt:Αίμα/Μυελός των οστών^Δότης:Ord: Synonyms: C MICRO Ord PrThr Pt Αίμα Αίμα/Μυελός των οστών Αντιγόνο Δότης Ιός Ιός ηπατίτιδας C Μυελός των οστών Οστό Πυρήνας ιού ηπατίτιδας C
es-ES	Spanish (Spain)	Core del virus hepatitis C Antígeno:PrThr:Punto temporal:Sangre o Médula osea^donante:Ord:
es-MX	Spanish (Mexico)	Ag del núcleo del virus de la hepatitis C:Presencia o umbral:Punto temporal:Donante de sangre o médula ósea:Ordinal:
fr-CA	French (Canada)	Hépatite C virus core, Ag:Présence-Seuil:Temps ponctuel:Sang/Moelle osseuse^Donneur:Ordinal:
fr-FR	French (France)	Hépatite C virus core Ag:Présence/Seuil:Ponctuel:Sang/Moelle osseuse^donneur:Qualitatif:
it-IT	Italian (Italy)	Epatite C virus, core, Ag:PrThr:Pt:Sangue/Mid os^donatore:Ord: Synonyms: Microbiologia Midollo osseo Presenza o Soglia Punto nel tempo (episodio) Sangue Sangue o Midollo Virus dell''epatite C Virus dell''epatite C core
nl-NL	Dutch (Netherlands)	Hepatitis C-virus core Ag:aanwezigheid:moment:bloed of beenmerg^donor:ordinaal: Synonyms: antigeen
pl-PL	Polish (Poland)	Rdzeń wirusa zapalenia wątroby typu C Ag:granica wykrywalności:punkt w czasie:krew lub szpik kostny^dawca:uporządkowany: Synonyms: Antygen rdzeniowy wirusa zapalenia wątroby typu C
pt-BR	Portuguese (Brazil)	Hepatite C vírus RNA painel:ACnc:Pt:Sg/MedOssea^doador:Ord: Synonyms: ; HCV; Hep C; Arbitrary concentration; Point in time; Random; BM; Bone marrow; BON; Bld/Mar; Blood; WB; Whole blood; Donr; Ql; Ordinal; QL; Qualitative; Qual; Screen; Antigen; Antigens; Hepatit; Hepatis; Microbiology
tr-TR	Turkish (Turkey)	Hepatitis C virüs core Ag:MevcEşik:Zmlı:Kan/kem il^verici:Srl: Synonyms: Antijen Mevcut
zh-CN	Chinese (China)	丙型肝炎病毒核心抗原:存在情况或阈值:时间点:全血/骨髓^供体:序数型: Synonyms: Ag C 型;丙;丙型 HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型丙型肝炎病毒（C 型肝炎病毒、HCV、Hep C、丙肝病毒、肝炎病毒 C 型）核心传染性肝炎传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体供血者;捐献者;捐赠者;给予体;给体;超系统 - 供体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型全血或骨髓;血液/骨髓;血液或骨髓存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间肝血;血液骨骼;骨头髓

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.