49896-4

Human papilloma virus 16+18+31+33+35+39+45+51+52+56+58+59+68 DNA [Presence] in Specimen by NAA with probe detection

Active

Part Description

LP28886-7 Human papilloma virus 16+18+31+33+35+39+45+51+52+56+58+59+68
The human papilloma viruses (HPVs) belong to the family Papillomaviridae, which are small, nonenveloped deoxyribonucleic acid (DNA) viruses. The HPV genome includes DNA sequences for six early (E1, E2, E4, E5, E6, and E7) and two late (L1 and L2) proteins. There are more than 100 types of HPV. The viruses can be classified into high and low risk types based on their ability to cause cancer. HPV is most often transmitted sexually but has been know to spread during nonsexual encounters and even rarely through fomites. At least 40 HPV types can infect the genital area. Most sexually active persons become infected with HPV at least once. HPV types 16 and 18 are oncogenic, high risk and cause most cervical, penile, vulvar, vaginal, anal and oropharyngeal cancers and precancers. Non oncogenic, low-risk HPV types (e.g., 6, 11) cause genital warts and recurrent respiratory papillomatosis. Since subclinical genital HPV infection generally clears spontaneously, treatment is only directed to the macroscopic (e.g., genital warts) or pathologic HPV-caused precancerous lesions. Cervical cancer is the only HPV-associated cancer for which routine screening is recommended. Vaccines are available to protect against oncogenic as well as common nononcogenic types. PMID: 27127735 [CDC:std/tg2015/hpv] [CDC:std/tg2015/hpv-cancer] Source: Regenstrief LOINC

Fully-Specified Name

Component: Human papilloma virus 16+18+31+33+35+39+45+51+52+56+58+59+68 DNA
Property: PrThr
Time: Pt
System: XXX
Scale: Ord
Method: Probe.amp.tar

Additional Names

Long Common Name: Human papilloma virus 16+18+31+33+35+39+45+51+52+56+58+59+68 DNA [Presence] in Specimen by NAA with probe detection
Short Name: HPV I/H Risk 1 DNA Spec Ql NAA+probe
Display Name: HPV 16+18+31+33+35+39+45+51+52+56+58+59+68 DNA NAA+probe Ql (Specimen)
Consumer Name Alpha Get Info: HPV 16+18+31+33+35+39+45+51+52+56+58+59+68, Specimen

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.22
Last Updated: Version 2.73 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 3359

Member of these Panels

LOINC	Long Common Name
86636-8	Family planning report - FPAR 2.0 set
54037-7	HEDIS 2009 panel
57820-3	HEDIS 2010 panel
60442-1	HEDIS 2011 panel
67767-4	HEDIS 2012 panel
72199-3	HEDIS 2013 panel
74234-6	HEDIS 2014 Value Sets
75868-0	HEDIS 2015 Value Sets
79544-3	HEDIS 2016 Value Sets
82955-6	HEDIS 2017 Value Sets
87625-0	HEDIS 2018 Value Sets

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Ιός ανθρωπίνων θηλωμάτων 16+18+31+33+35+39+45+51+52+56+58+59+68 DNA:PrThr:Pt:XXX:Ord:Ανιχνευτής.ενίσχυση.στόχου Synonyms: DNA PrThr Ιός Ιός ανθρώπινων θηλωμάτων Ιός ανθρώπινων θηλωμάτων 16 Ιός ανθρώπινων θηλωμάτων 16 & 18 Ιός ανθρώπινων θηλωμάτων 16+18 Ιός ανθρωπίνων θηλωμάτων 16+18+31+33+35+39+45+51+52+56+58+59+68
es-ES	Spanish (Spain)	Virus del Papiloma Humano 16+18+31+33+35+39+45+51+52+56+58+59+68 ADN:PrThr:Punto temporal:XXX:Ord:Sonda con amplificación dirigida
es-MX	Spanish (Mexico)	Virus del papiloma humano 16 + 18 + 31 + 33 + 35 + 39 + 45 + 51 + 52 + 56 + 58 + 59 + 68 ADN:Presencia o umbral:Punto temporal:XXX:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-CA	French (Canada)	Papillomavirus humain 16+18+31+33+35+39+45+51+52+56+58+59+68, ADN:Présence-Seuil:Temps ponctuel:XXX:Ordinal:Sonde avec amplification de la cible
fr-FR	French (France)	Papillomavirus humain 16+18+31+33+35+39+45+51+52+56+58+59+68 ADN:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:PCR amplification de cible
fr-BE	French (Belgium)	Papillomavirus humain 16+18+31+33+35+39+45+51+52+56+58+59+68 ADN:PrThr:Temps ponctuel:XXX:Ordinal:Sonde avec amplification de la cible Synonyms: HPV HPV 16+18+31+33+35+39+45+51+52+56+58+59+68 HPV 16 HPV 16+18
it-IT	Italian (Italy)	Papilloma virus umano 16+18+31+33+35+39+45+51+52+56+58+59+68 DNA:PrThr:Pt:XXX:Ord:Sonda.amp.tar Synonyms: Microbiologia Papilloma virus umano 16 e 18 Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	Humaan papillomavirus 16+18+31+33+35+39+45+51+52+56+58+59+68 DNA:aanwezigheid:moment:XXX:ordinaal:probe-detectie Synonyms: probe.amp.tar
pt-BR	Portuguese (Brazil)	Papiloma vírus humano 16+18+31+33+35+39+45+51+52+56+58+59+68 DNA:ACnc:Pt:XXX:Ord:Sonda com limite de detecção da amplificação de alvo Synonyms: ; HPV I/H Risk 1; Papilloma virus intermediate/high risk; HPV IHR; HPV16+18; Papilloma virus high risk; Human papillomavirus; Genital warts; Deoxyribonucleic acid; Arbitrary concentration; Point in time; Random; Misc; Miscellaneous; Unspecified; Other; Ql; Ordinal; QL; Qualitative; Qual; Screen; PCR; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; Microbiology
ru-RU	Russian (Russian Federation)	Вирус папилломы человека 16+18+31+33+35+39+45+51+52+56+58+59+68 ДНК:PrThr:ТчкВрм:XXX:Пор:Проба.усил.миш Synonyms: ДНК проба;ДНК зонд Порядковый Проба с мишени усилением Точка во времени;Момент
tr-TR	Turkish (Turkey)	Human papilloma virüsü 16+18+31+33+35+39+45+51+52+56+58+59+68 DNA:MevcEşik:Zmlı:XXX:Srl:Prob.amf.hdf Synonyms: Mevcut
zh-CN	Chinese (China)	人乳头瘤病毒 16+18+31+33+35+39+45+51+52+56+58+59+68 型 DNA:存在情况或阈值:时间点:XXX:序数型:探针法.基因扩增.靶向 Synonyms: HPV 16 & 18;HPV 16 & 18 型;HPV16 & 18;人类乳头瘤病毒 16 & 18 型;高危 HPV;高危型 HPV;高危型人乳头瘤病毒;高危型人类乳头瘤病毒 HPV 16;HPV 16 型;HPV16;人类乳头瘤病毒 16 型;高危 HPV;高危型 HPV;高危型人乳头瘤病毒;高危型人类乳头瘤病毒 HPV 16+18;HPV 16+18 型;HPV16+18;人类乳头瘤病毒 16+18 型;高危 HPV;高危型 HPV;高危型人乳头瘤病毒;高危型人类乳头瘤病毒 HPV 16+18+31+33+35+39+45+51+52+56+58+59+68 DNA HPV 16+18+31+33+35+39+45+51+52+56+58+59+68 型 DNA HPV 16+18+31+33+35+39+45+51+52+56+58+59+68;HPV 16+18+31+33+35+39+45+51+52+56+58+59+68 型;HPV I/H Risk 1;HPV IHR;HPV16+18+31+33+35+39+45+51+52+56+58+59+68;中/高危 HPV;中/高危型 HPV;中/高危型人乳头瘤病毒;中/高危型人类乳头瘤病毒;人类乳头瘤病毒 16+18+31+33+35+39+45+51+52+56+58+59+68 型 HPV;人乳头瘤病毒（Human papilloma virus，HPV）;人类乳头瘤病毒;生殖器疣 HPV16+18+31+33+35+39+45+51+52+56+58+59+68 DNA 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项人类乳头瘤病毒 16+18+31+33+35+39+45+51+52+56+58+59+68 型 DNA 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向去氧核糖核酸;脱氧核糖核酸去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA）存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间经过扩增的脱氧核糖核酸探针

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=49896-4

Third Party Copyright

This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.

This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.

Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.

LOINC Copyright

Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.