50079-3

17-Hydroxypregnenolone [Moles/volume] in Serum or Plasma --1 hour post 250 ug corticotropin

Active

Part Descriptions

LP17184-0 17-Hydroxypregnenolone
17-Hydroxypregnenolone (also 17-OH-pregnenolone and 17-alpha-hydroxypregnenolone), is a C21 steroid that is obtained by hydroxylation of pregnenolone at the C17-alpha position. This step is performed by the mitochondrial cytochrome P450 enzyme 17-hydroxylase (CYP17A1) that is present in the adrenal and gonads. Peak levels are reached in humans at the end of puberty and then decline. High levels are also achieved during pregnancy.
Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent. Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, 17-hydroxypregnenolone (Wikipedia)

LP17184-0 17-Hydroxypregnenolone
17-Hydroxypregnenolone, also known as 17-OH-PG, is a steroid hormone that is derived from cholesterol. 17-OH-PG is involved in the synthesis of cortisol, aldosterone and androstenedione in the adrenal glands. 17-OH-PG levels are measured to screen for congenital adrenal hyperplasia (CAH), a group of inherited disorders of the adrenal gland. High levels of 17-OH-PG in the blood indicate cortisol and aldosterone are not being produced in normal levels. PMID: 20077078 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: 17-Hydroxypregnenolone^1H post 250 ug corticotropin:SCnc:Pt:Ser/Plas:Qn:
Long Common Name: 17-Hydroxypregnenolone [Moles/volume] in Serum or Plasma --1 hour post 250 ug corticotropin
Short Name: 17OH-Preg 1h p 250 ug ACTH SerPl-sCnc
Display Name: 17-Hydroxypregnenolone 1 Hr post 250 ug corticotropin [Moles/Vol]
Consumer Name Alpha Get Info: 17-Hydroxypregnenolone 1 hr after 250 ug Corticotropin, Blood

Part Model Get Info

Component
17-Hydroxypregnenolone^1H post 250 ug corticotropin
LP307281-8
- Analyte
  17-Hydroxypregnenolone
  LP17184-0
  - Component Numerator
    17-Hydroxypregnenolone
    LP17184-0
    - Component Numerator Core
      17-Hydroxypregnenolone
      LP17184-0
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  1H post 250 ug corticotropin
  LP20518-4
- Adjustment
  NULL
- Count
  NULL
Property
SCnc
LP6860-3
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHAL.ROUTINE
Type: Laboratory
First Released: Version 2.22
Last Updated: Version 2.70 (MIN)
Change Reason: Changed Class from "CHAL" to "CHAL.ROUTINE"
Order vs. Observation: Observation

Member of these Groups Get Info

LOINC Group	Group Name
LG50342-1	17-Hydroxypregnenolone^1H post 250 ug corticotropin\|Pt\|Ser/Plas

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	17-hydroxypregnenolon^1 hodina po 250 ug kortikotropinu:Látková koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GR	Greek (Greece)	17-υδροξυπρογνενολόνη^1 ώρα κατόπιν 250 ug κορτικοτροπίνης:SCnc:Pt:Ορός/Πλάσμα:Qn: Synonyms: 1 ώρα κατόπιν 250 ug κορτικοτροπίνης 17-υδροξυπρογνενολόνη CHAL CHAL.ROUTINE Pt Qn SCnc Κορτικοτροπίνη Ορός Ορός/Πλάσμα Πλάσμα
es-ES	Spanish (Spain)	17-Hidroxipregnenolona^1 hora pos 250 ug corticotropina:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	17-hidroxipregnenolona^1H después de 250 ug de corticotropina:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:
fr-CA	French (Canada)	17-hydroxyprégnénolone^1 h post 250 ug hormone adrénocorticotrope:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR	French (France)	17-hydroxyprégnénolone^T01h après synacthène (250µg):Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE	French (Belgium)	17-hydroxyprégnénolone^1 h post 250 ug hormone adrénocorticotrope:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif: Synonyms: 1h après ACTH 250µg ACTH
it-IT	Italian (Italy)	17-Idrossipregnenolone^1h post 250 ug corticotropina:SCnc:Pt:Siero/Plasma:Qn: Synonyms: 1 ora dopo 250 ug di corticotropina Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma Test di provocazione
nl-NL	Dutch (Netherlands)	17-hydroxypregnenolon^60 min na 250 ug ACTH:mol/volume:moment:serum of plasma:kwantitatief: Synonyms: 1 uur na 250 ug ACTH adrenocorticotroop hormoon; adrenocorticotrofine; corticotrofine
pl-PL	Polish (Poland)	17-Hydroksypregnenolon^1h po 250 ug kortykotropiny:stężenie molowe:punkt w czasie:surowica lub osocze:ilościowy: Synonyms: 1 godzina po podaniu 250 ug ACTH ACTH Hormon adrenokortykotropowy
pt-BR	Portuguese (Brazil)	17-hidroxipregnenolona^60 min após 250 ug corticotrofina:SCnc:Pt:Sor/Plas:Qn: Synonyms: ; ACTH; Rc206; c74; Cortrosyn; c206; Adrenocorticotropin; Adrenocorticotrophic hormone; 17OH-Preg; 17 hydroxy pregnenolone; 17-alpha-Hydroxypregnenolone; 1H p 250 ug ACTH; Substance concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; mcg; PST; After; CHEMISTRY.CHALLENGE TESTING; CHEMISTRY.CHALLENGE TESTING
ru-RU	Russian (Russian Federation)	17-Гидроксипрегненолон^1 час после 250 мкг кортикотропина:МолКонц:ТчкВрм:Сыв/Плаз:Колич: Synonyms: Количественный Молярность;Молярная объёмная концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	17-Hidroksipregnenolon^1Sa snr 250 ug kortikotropin:SubKons:Zmlı:Ser/Plaz:Kant:
zh-CN	Chinese (China)	17-羟基孕烯醇酮^在给予250 ug促肾上腺皮质激素之后1小时:物质的量浓度:时间点:血清/血浆:定量型: Synonyms: 17-Alpha-羟基娠烯醇酮;17-Alpha-羟基孕 5 烯 3β醇 20 酮;17-Alpha-羟基孕烯诺龙;17-Alpha-羟基孕烯醇酮;17-Alpha-羟基孕甾烯醇酮;17OH-Preg;17-α-羟基娠烯醇酮;17-α-羟基孕 5 烯 3β醇 20 酮;17-α-羟基孕烯诺龙;17-α-羟基孕烯醇酮;17-α-羟基孕甾烯醇酮;17-羟基娠烯醇酮;17-羟基孕 5 烯 3β醇 20 酮;17-羟基孕烯诺龙;17-羟基孕甾烯醇酮;17-羟娠烯醇酮;17-羟孕 5 烯 3β醇 20 酮 1Hr之后于给予250 ug促肾上腺皮质激素;1Hr之后于给予250微克促肾上腺皮质激素;1小时之后于给予250 ug促肾上腺皮质激素;1小时之后于给予250微克促肾上腺皮质激素;60Min之后于给予250 ug促肾上腺皮质激素;60Min之后于给予250微克促肾上腺皮质激素;60分钟之后于给予250 ug促肾上腺皮质激素;60分钟之后于给予250微克促肾上腺皮质激素;在给予250 ug促肾上腺皮质激素之后1Hr;在给予250 ug促肾上腺皮质激素之后60Min;在给予250 ug促肾上腺皮质激素之后60 ACTH ACTH;亲皮质素;促皮质素 ug XXX刺激 - 在...之后 μg 之后于... 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺在...以后在后时刻;随机;随意;瞬间血清或血浆

Example Units

Unit	Source
nmol/L	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.