Version 2.77

Part Descriptions

LP17184-0   17-Hydroxypregnenolone
17-Hydroxypregnenolone (also 17-OH-pregnenolone and 17-alpha-hydroxypregnenolone), is a C21 steroid that is obtained by hydroxylation of pregnenolone at the C17-alpha position. This step is performed by the mitochondrial cytochrome P450 enzyme 17-hydroxylase (CYP17A1) that is present in the adrenal and gonads. Peak levels are reached in humans at the end of puberty and then decline. High levels are also achieved during pregnancy.
Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent. Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, 17-hydroxypregnenolone (Wikipedia)

LP17184-0   17-Hydroxypregnenolone
17-Hydroxypregnenolone, also known as 17-OH-PG, is a steroid hormone that is derived from cholesterol. 17-OH-PG is involved in the synthesis of cortisol, aldosterone and androstenedione in the adrenal glands. 17-OH-PG levels are measured to screen for congenital adrenal hyperplasia (CAH), a group of inherited disorders of the adrenal gland. High levels of 17-OH-PG in the blood indicate cortisol and aldosterone are not being produced in normal levels. PMID: 20077078 [Lab Tests Online:6-17hydroxy/tab/sample] Source: Regenstrief LOINC

Fully-Specified Name

Component
17-Hydroxypregnenolone^30M post 250 ug corticotropin
Property
SCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
17OH-Preg 30M p 250 ug ACTH SerPl-sCnc
Display Name
17-Hydroxypregnenolone 30 Min post 250 ug corticotropin [Moles/Vol]
Consumer Name Alpha Get Info
17-Hydroxypregnenolone 30 min after 250 ug Corticotropin, Blood

Basic Attributes

Class
CHAL
Type
Laboratory
First Released
Version 2.22
Last Updated
Version 2.70
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG50718-2 17-Hydroxypregnenolone^30M post 250 ug corticotropin|Pt|Ser/Plas

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) 17-Hidroxipregnenolona^30 minutos pos 250 ug corticotropina:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) 17-hidroxipregnenolona^30 M después de 250 ug de corticotropina:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:
fr-CA French (Canada) 17-hydroxyprégnénolone^30 min post 250 ug hormone adrénocorticotrope:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) 17-hydroxyprégnénolone T30min après synacthène (250µg):Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) 17-hydroxyprégnénolone^30 min post 250 ug hormone adrénocorticotrope:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: 30 min après ACTH 250µg ACTH
it-IT Italian (Italy) 17-Idrossipregnenolone^30Minuti post 250 ug corticotropina:SCnc:Pt:Siero/Plasma:Qn:
Synonyms: 30 minuti dopo 250 ug di corticotropina Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma Test di provocazione
nl-NL Dutch (Netherlands) 17-hydroxypregnenolon^30 min na 250 ug ACTH:mol/volume:moment:serum of plasma:kwantitatief:
Synonyms: 30M na 250 ug ACTH adrenocorticotroop hormoon; adrenocorticotrofine; corticotrofine
pt-BR Portuguese (Brazil) 17-Hidroxipregnenolona^30 min após 250 ug corticotrofina:SCnc:Pt:Sor/Plas:Qn:
Synonyms: ; ACTH; Rc206; c74; Cortrosyn; c206; Adrenocorticotropin; Adrenocorticotrophic hormone; 17OH-Preg; 17 hydroxy pregnenolone; 17-alpha-Hydroxypregnenolone; 30M p 250 ug ACTH; Substance concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; mcg; PST; After; CHEMISTRY.CHALLENGE TESTING; CHEMISTRY.CHALLENGE TESTING
ru-RU Russian (Russian Federation) 17-Гидроксипрегненолон^30 минут после 250 мкг кортикотропина:МолКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Молярность;Молярная объёмная концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) 17-Hidroksipregnenolon^30dk snr 250 ug kortikotropin:SubKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 17-羟基孕烯醇酮^在给予250 ug促肾上腺皮质激素之后30分钟:物质的量浓度:时间点:血清/血浆:定量型:
Synonyms: 0.5Hr之后于给予250 ug促肾上腺皮质激素;0.5Hr之后于给予250微克促肾上腺皮质激素;0.5小时之后于给予250 ug促肾上腺皮质激素;0.5小时之后于给予250微克促肾上腺皮质激素;30Min之后于给予250 ug促肾上腺皮质激素;30Min之后于给予250微克促肾上腺皮质激素;30分钟之后于给予250 ug促肾上腺皮质激素;30分钟之后于给予250微克促肾上腺皮质激素;在给予250 ug促肾上腺皮质激素之后0.5Hr;在给予250 ug促肾上腺皮质激素之后0.5小时;在给予250 ug促肾 17-Alpha-羟基娠烯醇酮;17-Alpha-羟基孕 5 烯 3β醇 20 酮;17-Alpha-羟基孕烯诺龙;17-Alpha-羟基孕烯醇酮;17-Alpha-羟基孕甾烯醇酮;17OH-Preg;17-α-羟基娠烯醇酮;17-α-羟基孕 5 烯 3β醇 20 酮;17-α-羟基孕烯诺龙;17-α-羟基孕烯醇酮;17-α-羟基孕甾烯醇酮;17-羟基娠烯醇酮;17-羟基孕 5 烯 3β醇 20 酮;17-羟基孕烯诺龙;17-羟基孕甾烯醇酮;17-羟娠烯醇酮;17-羟孕 5 烯 3β醇 20 酮 ACTH ACTH;亲皮质素;促皮质素 ug XXX刺激 - 在...之后 μg 之后于... 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 在...以后 在后 时刻;随机;随意;瞬间 血清或血浆

Example Units

Unit Source
nmol/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=50249-2