50366-4
Prolactin monomeric/Prolactin.total in Serum or Plasma
Active
Term Description
Prolactin is measured before and after PEG-treatment of the sample. The PEG treatment precipitates the macroprolactin and leaves the monomeric prolactin in the sample (more or less). The monomeric prolactin (prolactin result after PEG-treatment) is divided by the total prolactin (prolactin result before PEG-tratment) and the result multiplied with 100 yielding the percentage of monomeric prolactin.
Part Description
LP68274-7 Prolactin.monomeric
Monomeric prolactin is the most common form of circulating prolactin. Prolactin also has several isoforms, including the dimeric form ("big-prolactin") that has a molecular weight of ~50 kD and polymeric form ("big-big prolactin") that has a molecular weight of ~ 150 kD). Big-big prolactin, known as macroprolactin, and big prolactin are formed in the circulation after secretion of prolactin from the pituitary. They have a longer half-life than monomeric prolactin are not biologically active. However, typical prolactin assays do not differentiate between the different forms of prolactin, and the presence of big and big-big prolactin can lead to a false diagnosis of hyperprolactinemia. Methods such as PEG precipitation can separate macroprolactin and big prolactin from monomeric prolactin in order to obtain a more accurate measurement of biologically active prolactin, and chromatography can be used to further characterize the isoforms if necessary. PMCID: PMC3719302
Source: Regenstrief LOINC
,
Fully-Specified Name
- Component
- Prolactin.monomeric/Prolactin.total
- Property
- MFr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- Prolactin monomeric/Prolactin.total in Serum or Plasma
- Short Name
- Prolactin.monomeric/Total MFr SerPl
- Display Name
- Prolactin monomeric/Total prolactin [Mass fraction]
- Consumer Name Alpha Get Info
- Prolactin monomeric/Prolactin.total, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.22
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 5392
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: Prolaktin, monomer (rel.) |
de-DE | German (Germany) | Prolaktin.monomer/Prolaktin.gesamt: |
el-GR | Greek (Greece) | Προλακτίνη.μονομερής/Προλακτίνη.ολική: Synonyms: MFr Προλακτίνη Προλακτίνη.μονομερής |
es-ES | Spanish (Spain) | Prolactina monomérica/Prolactina.total: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Prolactina monomérica / prolactina total: |
fr-FR | French (France) | Prolactine monomérique/prolactine totale: |
it-IT | Italian (Italy) | Prolattina.monomerica/Prolattina.totale: Synonyms: Chimica Frazione di massa Plasma Prolattina monomerica Punto nel tempo (episodio) Siero Siero o Plasma |
nl-NL | Dutch (Netherlands) | prolactine.monomeer/prolactine.totaal: |
pt-BR | Portuguese (Brazil) | Prolactina.monomérica/Prolactina.total: Synonyms: Free prolactin; |
ru-RU | Russian (Russian Federation) | Пролактин.мономер/Пролактин.общий: Synonyms: Количественный Массовая доля Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | Prolaktin.monomerik/Prolaktin.total: |
zh-CN | Chinese (China) | 催乳素.单体/催乳素.总计: Synonyms: MFr PRL; |
Example Units
Unit | Source |
---|---|
% | Example UCUM Units |
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