Version 2.78

Part Description

LP14239-5   Influenza virus A
Influenza viruses, from the family Orthomyxoviridae, are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C are medically relevant to humans. Aquatic birds harboring avian IAV are the likely natural reservoir for all known IAV subtypes and are probably the original source of all human pandemic IAV strains. IAV maintained in wild birds have been associated with stable host switch events to novel hosts, including most often to domestic poultry but also to horses, swine, toothed whales and humans. The influenza virus life cycle begins with the binding of viral HA to host cell receptors. Endocytosis and HA-mediated fusion of the viral and cellular membranes occurs. Viral ribonucleoprotein complexes are released into the cytoplasm, travel to the nucleus, then are replicated and transcribed by the viral polymerase complex. The new viruses are formed and bud when the newly formed ribonucleicprotein complexes and structural proteins reach the plasma membrane. Further research is needed to better understand how IAVs switch hosts and the viral genetic changes that underlie human adaptation. IAV causes respiratory infections in humans ranging from asymptomatic to fatal. Pandemics are attributed to "novel" viruses which possess a viral hemagglutinin (HA) to which humans do not have immunity. PMID: 20542248 ] PMID: 25812763
Influenza viruses A and B are single-stranded RNA enveloped viruses belonging to the Orthomyxoviridae family. The symptoms of infection of Influenza A and B include fever, cough, sore throat, rhinorrhea, nasal congestion, headache, myalgia and malaise. Some patients may experience gastrointestinal symptoms including watery diarrhea, vomiting and abdominal pain. The influenza viruses spread rapidly in enclosed spaces with a documented rate of infection of 70% following a common source of exposure. Infection occurs in the respiratory epithelium in both the upper and lower respiratory tract, and the virus can be found in many specimen types, including nasal aspirates, nasal or nasopharyngeal swabs, throat swabs, sputum and tracheal aspirates. When infection rates reach epidemic proportions, hospitalization of children and elderly patients rises as does the mortality rates of elderly patients.(Manual of Clinical Microbiology, 11th edition, James H. Jorgensen; Karen C. Carroll; Guido Funke; Michael A Pfaller; Marie Louise Landry; Sandra S. Richter; David W. Warnock) Source: Regenstrief LOINC

Fully-Specified Name

Component
Influenza virus A Ag
Property
Prid
Time
Pt
System
Isolate
Scale
Nom
Method

Additional Names

Short Name
FLUAV Ag Islt
Display Name
FLUAV Ag Nom (Isol)
Consumer Name Alpha Get Info
Influenza A (Flu A) antigen

Example Answer List: LL2269-0

Source: Association of Public Health Laboratories
Answer Code Score Answer ID
H1 LA13508-9
H2 LA13509-7
H3 LA19220-5
H5 LA19221-3
H7 LA19222-1
H9 LA19223-9

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.22
Last Updated
Version 2.22
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG32757-3 Influenza virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Influenza-Virus A Ag:Nachweis oder Identität:Zeitpunkt:Isolat:Nominal:
es-ES Spanish (Spain) Virus Influenza A Antígeno:Presencia o identidad:Punto temporal:Aislado:Nom:
es-MX Spanish (Mexico) Virus de la influenza A Ag:Presencia o identidad:Punto temporal:Aislado:Nominal:
fr-CA French (Canada) Virus de l'influenza A, Ag:Présence ou identité:Temps ponctuel:Isolat:Nominal:
fr-FR French (France) Influenza virus A Ag:Identification:Ponctuel:Isolat:Résultat nominal:
fr-BE French (Belgium) Virus de l'influenza A Ag:Présence ou identité:Temps ponctuel:Isolat:Nominal:
Synonyms: Antigène FLU A virus FLU virus
it-IT Italian (Italy) Influenza A, virus, Ag:Prid:Pt:Isolato:Nom:
Synonyms: Microbiologia Presenza o Identità Punto nel tempo (episodio) Virus dell''influenza Virus dell''influenza A
nl-NL Dutch (Netherlands) Influenzavirus A Ag:identificator:moment:isolaat:nominaal:
Synonyms: antigeen
pl-PL Polish (Poland) Wirus grypy A Ag:wykrycie lub identyfikacja:punkt w czasie:izolat:cecha:
Synonyms: Antygen wirusa grypy typ A Wirus grypy Wirus grypy typ A
pt-BR Portuguese (Brazil) Influenza vírus A Ag:Ident:Pt:Isolado:Nom:
Synonyms: ; FLUAV; Avian influenza; Fowl plague; Influenza A virus; FLUA; Bird flu; FLUV; Influ; Identity or presence; Point in time; Random; Islt; Isol; Nominal; Antigen; Antigens; Microbiology
ru-RU Russian (Russian Federation) Грипп вирус А Аг:ПрИд:ТчкВрм:Изолят:Ном:
Synonyms: Номинальный;Именной Присутствие или Идентификация Точка во времени;Момент
tr-TR Turkish (Turkey) İnfluenza virüsü A Ag:MevcKimlik:Zmlı:İzolat:Snf:
Synonyms: Antijen
zh-CN Chinese (China) 流感病毒 A 型 抗原:存在与否或特征标识:时间点:分离株:名义型:
Synonyms: A 型 A 型抗原 A 型流感;A 型流感病毒;FLUA;FLUAV;家禽鼠疫;流感 A;流感 A 型;流感甲型;流感病毒甲型;甲型流感;甲型流感病毒;瘟疫;禽流感;禽流行性感冒;禽疫;鸡瘟 A 型流感病毒 Ag A 型流感病毒抗原 Ag FLUA Ag FLUA 抗原 FLUAV Ag FLUAV 抗原 FLUV;Influ;列性感冒病毒;流行性感冒病毒 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 分离物;分离菌;分离菌株;隔离种群 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 存在;存在与否;特征标识;身份;身份标识 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 流感病毒 A 型 Ag 流感病毒甲型 Ag 流感病毒甲型抗原 甲型流感病毒 Ag 甲型流感病毒抗原

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=50697-2