Version 2.77

Part Descriptions

LP14393-0   Ganglioside GD1a
Gangliosides are a family of molecules that are present throughout the body but especially prevalent in cells of the nervous system. Specific gangliosides are named for the carbohydrate sequence they contain and have a unique distribution within the nervous system. The oligosaccharide groups on gangliosides act as cell surface markers that play a role in cellular recognition and cell-to-cell communication, and they also act as specific receptors for certain pituitary glycoprotein hormones and certain bacterial protein toxins such as cholera toxin.
Anti-ganglioside antibodies, primarily IgG, are present in the sera from approximately 60% of patients with Guillain-Barré syndrome (GBS), and antibodies against different gangliosides are associated with different forms of GBS.
1. Antibodies against GD1a/GD1b and GD1b/GT1b complexes have been found in patients with more severe GBS requiring mechanical ventilation;
2. Antibodies against GM1 or those against GalNAc-GD1a have been associated with acute motor axonal neuropathy;
3. Anti-GQ1b antibodies are specifically associated with a variant of GBS called Fisher syndrome, which is characterized by ophthalmoplegia and ataxia.
Detection of specific markers early in the course of GBS may help guide the plan of care. PMID: 21214559 Source: Regenstrief LOINC, PMID: 2121455

LP222219-0   Ganglioside
A ganglioside molecule consists of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acid residues linked to the sugar chain. Molecules with one sialic acid residue are called monosialogangliosides (GM), those with two are called disialogangliosides (GD), and those with three are trisialogangliosides (GT). Gangliosides without any sialic acid residues are called asialogangliosides, while those that do not have a ceramide N-acyl group are called lysogangliosides. The number that typically is included at the end of the name indicates the order in which the molecule was discovered. For example, GM2 is a ganglioside with one sialic acid residue that was the second GM to be identified. Source: Regenstrief LOINC

Fully-Specified Name

Component
Ganglioside GD1a Ab.IgG/Ganglioside GD1a Ab.IgM
Property
Ratio
Time
Pt
System
Ser
Scale
Qn
Method
IA

Additional Names

Short Name
GD1a Gangl IgG/IgM Ser IA-Rto
Display Name
Ganglioside GD1a IgG/IgM IA (S) [Ratio]
Consumer Name Alpha Get Info
Ganglioside GD1a IgG/IgM Antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.22
Last Updated
Version 2.73
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Observation
Common Test Rank Get Info
9037

Member of these Panels

LOINC Long Common Name
82455-7 Ganglioside Ab panel - Serum

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Gangliosido GD1a IgG/Gangliósido GD1a IgM:Fracción:Punto temporal:Suero:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Gangliósido GD1a Ab.IgG / Gangliósido GD1a Ab.IgM:Proporción:Punto temporal:Suero:Cuantitativo:Inmunoensayo
fr-CA French (Canada) Ganglioside GD1a , IgG/Ganglioside GD1a , IgM:Ratios:Temps ponctuel:Sérum:Quantitatif:IA
fr-FR French (France) Ganglioside GD1a anticorps IgG/IgM:Ratio:Ponctuel:Sérum:Numérique:Immunoanalyse
it-IT Italian (Italy) Ganglioside GD1a Ab.IgG/Gangliosidi GD1a Ab.IgM:Rapporto:Pt:Siero:Qn:IA
Synonyms: Ab IgM ganglioside GD1a anticorpi IgG anticorpo Immunoassay Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) ganglioside GD1a As.IgG/ganglioside GD1a As.IgM:verhouding:moment:serum:kwantitatief:immunoassay
Synonyms: antistof; antilichaam IA
pt-BR Portuguese (Brazil) Gangliosideo GD1a Ac.IgG/Gangliosideo GD1a Ac.IgM:Ratio:Pt:Soro:Qn:Imunoensaio
Synonyms: Immune globulin M; Immunoglobulin M; Immune globulin G; Immunoglobulin G; GD1a Gangl; Rto; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
tr-TR Turkish (Turkey) Gangliozid GD1a Ab.IgG/Gangliozid GD1a Ab.IgM:Oran:Zmlı:Ser:Kant:İA
Synonyms: Ak Ak.IgG İmmünölçüm, immünoassay
zh-CN Chinese (China) 神经节苷脂 GD1a 抗体.IgG/神经节苷脂 GD1a 抗体.IgM:比率:时间点:血清:定量型:免疫测定法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 GD1a;神经节糖苷 GD1a 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 免疫球蛋白 G 免疫球蛋白 M 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 来自于不同体系的两个观察指标之比;比;比值 神经节糖苷 神经节苷脂 GD1a Ab 神经节苷脂 GD1a Ab.IgG 神经节苷脂 GD1a Ab.IgM 神经节苷脂 GD1a IgG 神经节苷脂 GD1a IgM 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit Source
{Index_val} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=50767-3