Version 2.78

Part Descriptions

LP207365-0   Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4   Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

Fully-Specified Name

Component
Coxsackievirus B4 Ab.Neut
Property
Titr
Time
Pt
System
Ser
Scale
SemiQn
Method
Neut

Additional Names

Long Common Name
Coxsackievirus B4 neutralizing antibody [Titer] in Serum by Neutralization test
Short Name
CV B4 NAb Titr Ser Nt
Display Name
Coxsackievirus B4 neut ab Neut test (S) [Titer]
Consumer Name Alpha Get Info
Coxsackievirus B4 neutralizing antibody, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.75
Change Reason
Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
Order vs. Observation
Both
Common Test Rank Get Info
6792

Member of these Panels

LOINC Long Common Name
41486-2 Coxsackievirus B neutralizing Ab panel [Titer] - Serum by Neutralization test

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Coxsackie-Virus B4 Ak.neutralisierend:Titer:Zeitpunkt:Serum:Semiquantitativ:Neutralisationstest
es-AR Spanish (Argentina) [anticuerpo anti - ] virus Coxsackie B4 [Ac]:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:neutralización
es-ES Spanish (Spain) Virus Coxsackie B4 Anticuerpos antineutrófilos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Prueba de neutralización
Synonyms: Semicuantitativo
es-MX Spanish (Mexico) Coxsackievirus B4 Ab:Título:Punto temporal:Suero:Cuantitativo:Prueba de neutralización
fr-FR French (France) Coxsackievirus B4 Ac neutralisant:Titre:Ponctuel:Sérum:Semi-Quantitatif:Neutralisation
fr-CA French (Canada) Coxsackievirus B4 Ac.neut:Titre:Temps ponctuel:Sérum:SemiQn:Test de neutralisation
it-IT Italian (Italy) Coxsackievirus B4 Ab.Neut:Titr:Pt:Siero:SemiQn:Neut
Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Siero Test di neutralizzazione Titolo
ko-KR Korean (Korea, Republic Of) 콕사키바이러스 B4 항체:역가:검사시점:혈청:정량:중화
nl-NL Dutch (Netherlands) Coxsackievirus B4 As.neutraliserend:titer:moment:serum:semikwantitatief:neutralisatietest
Synonyms: antistof; antilichaam
pl-PL Polish (Poland) Wirus Coxsackie B4 Ab.Neutralizujące:miano:punkt w czasie:surowica:półilościowy:test neutralizacji
Synonyms: Przeciwciała do wirusa Coxsackie B4 Przeciwciała neutralizujące do wirusa Coxsackie B4 Wirus Coxsackie Wirus Coxsackie B4
pt-BR Portuguese (Brazil) Coxsackie vírus B4 Ac:Título:Pt:Soro:Qn:Teste de neutralização
Synonyms: ; CV B4; Coxsackie; Coxsackie virus; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
uk-UA Ukrainian (Ukraine) Вірус Коксакі B4 Антитіла.Нейтралізуючі:Титр:МоментЧасу:Сироватка:Кількісно:Нейтралізації тест
Synonyms: ABS; Aby; Antby; Anti; Antibodies; Antibody; Autoantibodies; Autoantibody; CAV; Conventional virus neutralization test; Coxsackie; Coxsackie virus; CV; CV B4; cVNT; Dilution factor; Dilution Factor (Titer); ID; Infectious Disease; InfectiousDisease; Microbiology; NAb; NEUTRALIZATION; Neutralization test; NT; Point in time; QNT; Quan; Quant; Quantitative; Random; Serum; Serum virus neutralization; SR; SVN; Titer; Titered; Titre; Ttr; Virus neutralization test; VNT
zh-CN Chinese (China) 柯萨奇病毒 B4 型 抗体.中和:滴定度:时间点:血清:半定量型:中和试验
Synonyms: Ab;自身抗体 Coxsackie;CV;柯萨基病毒;考克塞基病毒 CV B4 Ab CV B4 型 Ab CV B4 型抗体 CV B4 抗体 CV B4;CV B4 型;柯萨基病毒 B4 型;考克塞基病毒 B4 型 中和试验;中和抗体;中和 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 柯萨基病毒 B4 型 Ab 柯萨基病毒 B4 型抗体 柯萨奇病毒 B4 型 Ab 考克塞基病毒 B4 型 Ab 考克塞基病毒 B4 型抗体

Example Units

Unit Source
titer REGENSTRIEF
{titer} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=5109-4