5117-7
Cryoglobulin [Presence] in Serum
Active
Part Description
LP15516-5 Cryoglobulin
Serum cryoglobulins are immunoglobulins that, in vitro, precipitate at temperatures below 37°C and redissolve on rewarming.Cryoglobulins can be transient and without clinical implications or they can be a marker of significant disease. Monoclonal cryoglobulins, which are IgG, IgM, or IgA, or monoclonal free light chains, are usually associated with haematological disorders. Mixed cryoglobulins, which contain polyclonal immunoglobulins with or without a monoclonal component, are found in many infectious and systemic disorders. There is a significant association between essential mixed cryoglobulinaemia and hepatitis C virus infection (> 90%). PMID: 11825916
Source: Regenstrief LOINC
, PMID: 11825916
Reference Information
| Type | Source | Reference |
|---|---|---|
| Mapping Guidance | Regenstrief Help | Use of plasma specimen in addition to serum permits detection of cryofibrinogenemia. Cooling serum detects only cryoglobulin. To detect cryofibrinogen, one has to test plasma which will detect cryoglobulin and/or cryofibrinogen. Cryofibrinogen is inferred when cold challenge to both serum and plasma only shows an effect on plasma. Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations |
Fully-Specified Name
- Component
- Cryoglobulin
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
Additional Names
- Long Common Name
- Cryoglobulin [Presence] in Serum
- Short Name
- Cryoglob Ser Ql
- Display Name
- Cryoglobulin Ql (S)
- Consumer Name Alpha Get Info
- Cryoglobulin, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73 (MIN)
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 2534
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 74352-6 | Cryoglobulin and cryofibrinogen panel - Serum and Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Kryoglobulin: |
| de-AT | German (Austria) | Synonyms: Kryoglobuline qual. |
| el-GR | Greek (Greece) | Κρυοσφαιρίνη: Synonyms: PrThr Κρυοσφαιρίνη |
| es-AR | Spanish (Argentina) | crioglobulina: |
| es-MX | Spanish (Mexico) | Crioglobulina: |
| es-ES | Spanish (Spain) | Crioglobulina: |
| et-EE | Estonian (Estonia) | Krüoglobuliin: Synonyms: Järgarvuline Juhuslik Seerum |
| fr-FR | French (France) | Cryoglobulines: |
| fr-BE | French (Belgium) | Cryoglobuline: |
| fr-CA | French (Canada) | Cryoglobuline: |
| it-IT | Italian (Italy) | Crioglobulina: Synonyms: Chimica Presenza o Soglia Punto nel tempo (episodio) Siero |
| ko-KR | Korean (Korea, Republic Of) | 한랭글로불린: |
| nl-NL | Dutch (Netherlands) | cryoglobuline: |
| pt-BR | Portuguese (Brazil) | Crioglobulina: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Криоглобулин: Synonyms: Порядковый Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | Kriyoglobulin: Synonyms: Mevcut |
| uk-UA | Ukrainian (Ukraine) | Кріоглобулін: Synonyms: Chemistry; |
| zh-CN | Chinese (China) | 冷球蛋白: Synonyms: Cryo; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=5117-7
LOINC Copyright
Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://