5198-7

Hepatitis C virus Ab [Units/volume] in Serum by Immunoassay

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Part Description

LP14400-3 Hepatitis C virus
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

Reference Information

Type	Source	Reference
Mapping Guidance	Regenstrief Help	NOTE: You may really want to map to LOINC 48159-8, signal to cut off ratio (S/CO), which is also included in this table. Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations

LOINC Names Get Info

Fully-Specified Name: Hepatitis C virus Ab:ACnc:Pt:Ser:Qn:IA
Long Common Name: Hepatitis C virus Ab [Units/volume] in Serum by Immunoassay
Short Name: HCV Ab Ser IA-aCnc
Display Name: HCV Ab IA Qn (S)
Consumer Name Alpha Get Info: Hepatitis C virus (HCV) antibody, Blood

Part Model Get Info

Component
Hepatitis C virus Ab
LP38332-0
- Analyte
  Hepatitis C virus Ab
  LP38332-0
  - Component Numerator
    Hepatitis C virus Ab
    LP38332-0
    - Component Numerator Core
      Hepatitis C virus
      LP14400-3
    - Component Numerator Core Suffix
      Ab
      LP20667-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
ACnc
LP6773-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Qn
LP7753-9
Method
IA
LP217197-5

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 1.0
Last Updated: Version 2.73 (MIN)
Change Reason: The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 1617

Member of these Panels

LOINC	Long Common Name
75886-2	HCV antibody screening - Meaningful Use set

Member of these Groups Get Info

LOINC Group	Group Name
LG32754-0	Hepatitis C virus

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Virus hepatitidy C Ab:Arbitrární koncentrace:Časový bod:Sérum:Kvantitativní:Imunoanalýza
de-AT	German (Austria)	Synonyms: HCV-Antikörper quantitativ
de-DE	German (Germany)	Hepatitis-C-Virus Ak:Arbiträre Konzentration:Zeitpunkt:Serum:Quantitativ:Immunoassay Synonyms: Hepacivirus C; HCV
el-GR	Greek (Greece)	Ιός Ηπατίτιδας C Αντίσωμα:ACnc:Pt:Ορός:Qn:IA Synonyms: ACnc C IA MICRO Pt Qn Αντίσωμα Ιός Ιός ηπατίτιδας C Ορός
es-AR	Spanish (Argentina)	[anticuerpo anti - ] virus de hepatitis C [Ac]:concentración arbitraria:punto en el tiempo:suero:cuantitativo:enzimoinmunoanálisis
es-ES	Spanish (Spain)	Virus Hepatitis C Anticuerpos:Concentración arbitraria:Punto temporal:Suero:Qn:IA Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Virus de la hepatitis C Ab:Concentración arbitraria:Punto temporal:Suero:Cuantitativo:Inmunoensayo
et-EE	Estonian (Estonia)	C-hepatiidi viirus antikehad:Acnc:Pt:S:Qn:IA Synonyms: Juhuslik Kvantitatiivne Seerum
fr-CA	French (Canada)	Virus de l'hépatite C, Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
fr-FR	French (France)	Hépatite C virus Ac:Arbitraire/Volume:Ponctuel:Sérum:Numérique:Immunoanalyse
fr-BE	French (Belgium)	Virus de l'hépatite C Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA Synonyms: Anticorps HCV
it-IT	Italian (Italy)	Epatite C, virus Ab:ACnc:Pt:Siero:Qn:IA Synonyms: anticorpo Concentrazione Arbitraria Immunoassay Microbiologia Punto nel tempo (episodio) Siero Virus dell''epatite C
ko-KR	Korean (Korea, Republic Of)	C형 간염 바이러스 항체:임의농도:검사시점:혈청:정량:효소면역측정법
nl-NL	Dutch (Netherlands)	Hepatitis C-virus As:eenheid/volume:moment:serum:kwantitatief:immunoassay Synonyms: antistof; antilichaam IA
pl-PL	Polish (Poland)	Wirus zapalenia wątroby typu C Ab:stężenie w jednostkach umownych:punkt w czasie:surowica:ilościowy:metoda immunologiczna Synonyms: Przeciwciała do wirusa zapalenia wątroby typu C
pt-BR	Portuguese (Brazil)	Hepatite C vírus Ac:ACnc:Pt:Soro:Qn:Imunoensaio Synonyms: HCVAc; Hep C; HCV; Arbitrary concentration; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Hepatit; Hepatis; Microbiology
ru-RU	Russian (Russian Federation)	Гепатита С вирус Ат:ПроизвКонц:ТчкВрм:Сыв:Колич:IA Synonyms: Антитело Количественный Произвольная концентрация Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	Hepatit C virüsü Ab:SçKons:Zmlı:Ser:Kant:İA Synonyms: Ak İmmünölçüm, immünoassay
uk-UA	Ukrainian (Ukraine)	Вірус Гепатиту С Антитіла:Довільна Концентрація:МоментЧасу:Сироватка:Кількісно:Імуноаналіз Synonyms: ABS; Aby; Antby; Anti; Antibodies; Antibody; Arbitrary concentration; Autoantibodies; Autoantibody; EIA; ELFA; ELISA; Enzyme immunoassay; HCV; HCVAB; Hep; Hep C; Hepatis; Hepatit; Hepatology; IAA; ID; Infectious Disease; InfectiousDisease; Liver; MEIA; Microbiology; Point in time; QNT; Quan; Quant; Quantitative; Random; Serum; SR; SUDS; UniversalLabOrders
zh-CN	Chinese (China)	丙型肝炎病毒抗体:任意型浓度:时间点:血清:定量型:免疫测定法 Synonyms: Ab;自身抗体 C 型;丙;丙型 HCV Ab HCV 抗体 HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 HCVAb Hep C Ab Hep C 抗体丙型肝炎病毒 Ab 丙肝病毒 Ab 丙肝病毒抗体任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度传染性肝炎传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验可用数量表示的;定量性;数值型;数量型;连续数值型标尺微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间肝肝炎病毒 C 型 Ab 肝炎病毒 C 型抗体

Example Units

Unit	Source
{index_val}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.