5233-2
Intrinsic factor Ab [Presence] in Serum by Radioimmunoassay (RIA)
Active
Part Descriptions
LP15673-4 Intrinsic factor
Intrinsic factor is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of vitamin B12 later on in the small intestine. Upon entry into the stomach, vitamin B12 becomes bound to one of two B12 binding proteins present in gastric juice. In the less acidic environment of the small intestine, these proteins dissociate from the vitamin, enabling it to bind to intrinsic factor and enter the portal circulation through a receptor in the ileal mucosa specific for the B12 -intrinsic factor complex. In pernicious anemia, an autoimmune disease, autoantibodies directed against intrinsic factor or parietal cells themselves lead to an intrinsic factor deficiency, malabsorption of vitamin B12, and subsequent megaloblastic anemia. Atrophic gastritis can also cause intrinsic factor deficiency and anemia through damage to the parietal cells of the stomach wall.
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Source: Wikipedia, intrinsic factor (Wikipedia)
LP15673-4 Intrinsic factor
A glycoprotein secreted by the cells of the gastric glands that is required for the absorption of VITAMIN B 12. Deficiency of intrinsic factor results in ANEMIA, PERNICIOUS.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Intrinsic factor Ab
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- RIA
Additional Names
- Short Name
- IF Ab Ser Ql RIA
- Display Name
- Intrinsic factor Ab RIA Ql (S)
- Consumer Name Alpha Get Info
- Intrinsic factor antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 18809
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG8731-4 | Intrinsic factor Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Intrinsic Factor Ak: Synonyms: RIA |
es-AR | Spanish (Argentina) | [anticuerpo anti - ] factor intrínsico [Ac]: |
es-ES | Spanish (Spain) | Factor intrínseco Anticuerpos: |
es-MX | Spanish (Mexico) | Factor intrínseco Ab: |
et-EE | Estonian (Estonia) | Sisemine faktor antikehad: Synonyms: Järgarvuline Juhuslik Radioimmuunmeetod Seerum |
fr-CA | French (Canada) | Facteur intrinsèque, Ac: |
fr-FR | French (France) | Facteur intrinsèque anticorps: |
fr-BE | French (Belgium) | Facteur intrinsèque Ac: Synonyms: Anticorps FI Radio-immuno-essai |
it-IT | Italian (Italy) | Fattore intrinseco Ab: Synonyms: anticorpo Dosaggio radioimmulogico (RIA) Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
ko-KR | Korean (Korea, Republic Of) | 내재 인자 항체: |
nl-NL | Dutch (Netherlands) | intrinsieke factor As: Synonyms: antistof; |
pl-PL | Polish (Poland) | Czynnik wewnętrzny Ab: Synonyms: metoda radioimmunologiczna (RIA) Przeciwciała do czynnika wewnętrznego Castle''a |
pt-BR | Portuguese (Brazil) | Fator intrínseco Ac: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Внутренний фактор Ат: Synonyms: Антитело Порядковый Радиоиммуноанализ (РИА) Сыворотка Точка во времени; |
tr-TR | Turkish (Turkey) | İntrinsik faktör Ab: Synonyms: Ak Mevcut |
zh-CN | Chinese (China) | 内因子 抗体: Synonyms: Ab; |
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