52984-2
Cytomegalovirus IgG Ab avidity [Ratio] in Serum or Plasma by Immunoassay
Active
Part Description
LP14255-1 Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Cytomegalovirus Ab.IgG avidity
- Property
- Ratio
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
- IA
Additional Names
- Long Common Name
- Cytomegalovirus IgG Ab avidity [Ratio] in Serum or Plasma by Immunoassay
- Short Name
- CMV IgG Avidity SerPl IA-Rto
- Display Name
- CMV IgG avidity IA [Ratio]
- Consumer Name Alpha Get Info
- Cytomegalovirus (CMV) IgG avidity, Blood
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.24
- Last Updated
- Version 2.73
- Change Reason
- Property has been changed from ACnc to reflect the fact that avidity by definition is a ratio.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.; Updated System from Ser to Ser/Plas since this test can also be performed on plasma.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 5237
Formula (Readable)
Avidity % = (absorbance of avidity CMV IgG well/absorbance of standard CMV IgG well)x100
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
| 75868-0 | HEDIS 2015 Value Sets |
| 79544-3 | HEDIS 2016 Value Sets |
| 82955-6 | HEDIS 2017 Value Sets |
| 87625-0 | HEDIS 2018 Value Sets |
| 90766-7 | HEDIS 2019 Value Sets |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: CMV-IgG Avidität |
| de-DE | German (Germany) | Cytomegalie-Virus Ak.IgG-Avidität: Synonyms: CMV |
| es-ES | Spanish (Spain) | Citomegalovirus Avidez IgG: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Citomegalovirus Ab.IgG avidez: |
| et-EE | Estonian (Estonia) | Tsütomegaloviirus antikehad.IgG aviidsus: Synonyms: Immuunglobuliin G Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Cytomégalovirus, Ac.avidité des IgG: |
| fr-FR | French (France) | Cytomégalovirus Ac IgG avidité: |
| fr-BE | French (Belgium) | Cytomégalovirus Anticorps.avidité des IgG: Synonyms: Anticorps CMV |
| it-IT | Italian (Italy) | Citomegalovirus Ab.avidità IgG: Synonyms: anticorpi IgG anticorpo Avidità delle IgG; |
| nl-NL | Dutch (Netherlands) | Cytomegalovirus As.IgG-aviditeit: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Wirus cytomegalii Ab.IgG awidność: Synonyms: Awdiność przecwciał do cytomegalowirusa w klasie IgG Cytomegalowirus IgG Przecwciała do cytomegalowirusa Przecwciała IgG do cytomegalowirusa |
| pt-BR | Portuguese (Brazil) | Citomegalovírus Ac.IgG avidez: Synonyms: Immune globulin G; |
| ru-RU | Russian (Russian Federation) | Цитомегаловирус Ат.IgG авидность: Synonyms: Антитело Количественный Коэффициент; |
| tr-TR | Turkish (Turkey) | Cytomegalovirus Ab.IgG avidite: Synonyms: Ak Ak.IgG Ak.IgG avidite İmmünölçüm, immünoassay |
| zh-CN | Chinese (China) | 巨细胞病毒 抗体.IgG 亲合力: Synonyms: Ab.IgG 亲合力; |
Example Units
| Unit | Source |
|---|---|
| % | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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LOINC Copyright
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