53023-8
Tissue transglutaminase Ab [Presence] in Serum
Active
Part Descriptions
LP40012-4 Tissue transglutaminase Ab
Anti-transglutaminase antibodies (ATA) are antibodies found more frequently in certain autoimmune diseases. High levels (titers) of ATA are found in almost all instances of coeliac disease. Given the association of ATA with coeliac disease, and the prevalence of the latter it is estimated that ~1% of the population have potentially pathogenic levels of ATA.
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Source: Wikipedia
, Wikipedia
LP40012-4 Tissue transglutaminase Ab
Tissue transglutaminase (abbreviated as TG2 or tTG) is an enzyme (EC 2.3.2.13) of the transglutaminase family. Like other transglutaminases, it crosslinks proteins between an ε-amino group of a lysine residue and a γ-carboxamide group of glutamine residue, creating an inter- or intramolecular bond that is highly resistant to proteolysis (protein degradation). It is an autoantigen in celiac disease, and is also known to play a role in apoptosis, cellular differentiation and matrix stabilisation. Serology for anti-tTG antibodies has superseded older serological tests (anti-endomysium, anti-gliadin and anti-reticulin) and has a strong sensitivity (99%) and specificity (>90%) for identifying coeliac disease. Modern anti-tTG assays rely on a human recombinant protein as an antigen.
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Source: Wikipedia
, Wikipedia
Fully-Specified Name
- Component
- Tissue transglutaminase Ab
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
Additional Names
- Long Common Name
- Tissue transglutaminase Ab [Presence] in Serum
- Short Name
- tTG Ab Ser Ql
- Display Name
- tTG Ab Ql (S)
- Consumer Name Alpha Get Info
- tTG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.24
- Last Updated
- Version 2.73 (MIN)
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 5494
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: tTGA ql. |
de-DE | German (Germany) | Gewebetransglutaminase Ak: Synonyms: Transglutaminase |
el-GR | Greek (Greece) | Ιστική τρανσγλουταμινάση Αντίσωμα: Synonyms: PrThr Ιστική τρανσγλουταμινάση |
es-ES | Spanish (Spain) | Transglutaminasa tisular Anticuerpos: |
es-MX | Spanish (Mexico) | Transglutaminasa tisular Ab: |
et-EE | Estonian (Estonia) | Koe transglutaminaas antikehad: Synonyms: Järgarvuline Juhuslik Seerum |
fr-CA | French (Canada) | Transglutaminase de tissu, Ac: |
fr-FR | French (France) | Transglutaminase tissulaire anticorps: |
fr-BE | French (Belgium) | Transglutaminase de tissu Ac: Synonyms: Anticorps |
it-IT | Italian (Italy) | Transglutaminasi tissutale Ab: Synonyms: anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | tissue transglutaminase As: Synonyms: antistof; |
pl-PL | Polish (Poland) | Transglutaminaza tkankowa Ab: |
pt-BR | Portuguese (Brazil) | Transglutaminase tecidual Ac: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Тканевая трансглутаминаза Ат: Synonyms: Антитело Порядковый Сыворотка Точка во времени; |
tr-TR | Turkish (Turkey) | Doku transglutaminaz Ab: Synonyms: Mevcut |
zh-CN | Chinese (China) | 组织谷氨酰胺转移酶 抗体: Synonyms: Ab; |
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