LOINC
Version 2.67

53023-8Tissue transglutaminase Ab [Presence] in SerumActive

Part Descriptions

LP40012-4   Tissue transglutaminase Ab
Anti-transglutaminase antibodies (ATA) are antibodies found more frequently in certain autoimmune diseases. High levels (titers) of ATA are found in almost all instances of coeliac disease. Given the association of ATA with coeliac disease, and the prevalence of the latter it is estimated that ~1% of the population have potentially pathogenic levels of ATA. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP40012-4   Tissue transglutaminase Ab
Tissue transglutaminase (abbreviated as TG2 or tTG) is an enzyme (EC 2.3.2.13) of the transglutaminase family. Like other transglutaminases, it crosslinks proteins between an ε-amino group of a lysine residue and a γ-carboxamide group of glutamine residue, creating an inter- or intramolecular bond that is highly resistant to proteolysis (protein degradation). It is an autoantigen in celiac disease, and is also known to play a role in apoptosis, cellular differentiation and matrix stabilisation. Serology for anti-tTG antibodies has superseded older serological tests (anti-endomysium, anti-gliadin and anti-reticulin) and has a strong sensitivity (99%) and specificity (>90%) for identifying coeliac disease. Modern anti-tTG assays rely on a human recombinant protein as an antigen. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Fully-Specified Name

Component
Tissue transglutaminase Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method

Additional Names

Short Name
tTG Ab Ser Ql
Display Name
tTG Ab Ql (S)

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.24
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (CHINA)
组织谷氨酰胺转移酶 抗体:存在情况或阈值:时间点:血清:序数型:
nl-NLDutch (NETHERLANDS)
tissue transglutaminase As:aanwezigheid:moment:serum:ordinaal:
et-EEEstonian (ESTONIA)
Koe transglutaminaas antikehad:PrThr:Pt:S:Ord:
fr-BEFrench (BELGIUM)
Transglutaminase de tissu Ac:PrThr:Temps ponctuel:Sérum:Ordinal:
fr-CAFrench (CANADA)
Transglutaminase de tissu , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:
fr-FRFrench (FRANCE)
Tissue transglutaminase Ab:PrThr:Pt:Ser:Ord:
de-ATGerman (AUSTRIA)
tTGA ql.
de-DEGerman (GERMANY)
Gewebetransglutaminase Ak:AKnz:Pkt:Ser:Ord:
el-GRGreek (GREECE)
Ιστική τρανσγλουταμινάση Αντίσωμα:PrThr:Χρονική στιγμή:Ορός:Τακτική:
it-ITItalian (ITALY)
Transglutaminasi tissutale , Ab:PrThr:Pt:Siero:Ord:
pt-BRPortuguese (BRAZIL)
Transglutaminase tecidual Ac:ACnc:Pt:Soro:Ord:
ru-RURussian (RUSSIAN FEDERATION)
Тканевая трансглутаминаза Ат:PrThr:ТчкВрм:Сыв:Пор:
es-ESSpanish (SPAIN)
Transglutaminasa tisular Anticuerpos:PrThr:Punto temporal:Suero:Ord:
tr-TRTurkish (TURKEY)
Doku transglutaminaz Ab:MevcEşik:Zmlı:Ser:Srl:

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=53023-8